Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Andrew J Jezewski"'
Autor:
Andrew J Jezewski, Ann M Guggisberg, Dana M Hodge, Naomi Ghebremichael, Gavin Nicholas John, Lisa K McLellan, Audrey Ragan Odom John
Publikováno v:
PLoS Pathogens, Vol 18, Iss 9, p e1010803 (2022)
Efforts to control the global malaria health crisis are undermined by antimalarial resistance. Identifying mechanisms of resistance will uncover the underlying biology of the Plasmodium falciparum malaria parasites that allow evasion of our most prom
Externí odkaz:
https://doaj.org/article/0857274aac9747b18b203483e05f38fe
Autor:
Rachel L Edwards, Isabel Heueck, Soon Goo Lee, Ishaan T Shah, Justin J Miller, Andrew J Jezewski, Marwa O Mikati, Xu Wang, Robert C Brothers, Kenneth M Heidel, Damon M Osbourn, Carey-Ann D Burnham, Sophie Alvarez, Stephanie A Fritz, Cynthia S Dowd, Joseph M Jez, Audrey R Odom John
Publikováno v:
PLoS Pathogens, Vol 16, Iss 6, p e1007806 (2020)
Coagulase-positive staphylococci, which frequently colonize the mucosal surfaces of animals, also cause a spectrum of opportunistic infections including skin and soft tissue infections, urinary tract infections, pneumonia, and bacteremia. However, re
Externí odkaz:
https://doaj.org/article/5dc53d519c85411dae65c54b8c5190b9
Autor:
Laura C. Ristow, Andrew J. Jezewski, Benjamin J. Chadwick, Mark A. Stamnes, Xiaorong Lin, Damian J. Krysan
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Cryptococcus spp. are environmental fungi that first must adapt to the host environment before they can cause life-threatening meningitis in immunocompromised patients. Host CO2 concentrations are 100-fold higher than the external environmen
Externí odkaz:
https://doaj.org/article/4566e417213e44cb95d77a498fd0705a
Autor:
Marion Vanneste, Anita Venzke, Soumitra Guin, Andrew J. Fuller, Andrew J. Jezewski, Sarah R. Beattie, Damian J. Krysan, Marvin J. Meyers, Michael D. Henry
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionAn attractive, yet unrealized, goal in cancer therapy is repurposing psychiatric drugs that can readily penetrate the blood-brain barrier for the treatment of primary brain tumors and brain metastases. Phenothiazines (PTZs) have demonstra
Externí odkaz:
https://doaj.org/article/4334b357eab940c8a068c9537ffc9a99
Publikováno v:
mSphere, Vol 7, Iss 3 (2022)
ABSTRACT There is an urgent need for new antifungals to treat cryptococcal meningoencephalitis, a leading cause of mortality in people living with HIV/AIDS. An important aspect of antifungal drug development is the validation of targets to determine
Externí odkaz:
https://doaj.org/article/90283ac21d334841b8e9d5b29829280e
Publikováno v:
Microbiology Spectrum. 11
Cryptococcus neoformans causes life-threatening infections of the brain. The most effective treatment regimens are based on flucytosine-based combination therapy, which has led to increasingly successful broadening of access to flucytosine globally.
Publikováno v:
mBio. 13(4)
Cryptococcus neoformans is an important human fungal pathogen for which the external environment is its primary niche. Previous work has shown that two nonessential acetyl-CoA metabolism enzymes, ATP-citrate lyase (
Publikováno v:
Microbiology Spectrum. 10
Cryptococcus neoformans is a fungal pathogen that contributes to nearly 180,000 deaths annually. We characterized a gene named GNK1 that appears to interact with other genetic loci involved with the ability of C. neoformans to act as a pathogen.
Autor:
Andrew J. Jezewski, Ann M. Guggisberg, Dana M. Hodge, Naomi Ghebremichael, Gavin Nicholas John, Lisa K. McLellan, Audrey Ragan Odom John
Publikováno v:
PLoS pathogens. 18(9)
Efforts to control the global malaria health crisis are undermined by antimalarial resistance. Identifying mechanisms of resistance will uncover the underlying biology of the Plasmodium falciparum malaria parasites that allow evasion of our most prom
Autor:
Ann M. Guggisberg, Lisa K. McLellan, Andrew J. Jezewski, Dana M. Hodge, Audrey R. Odom John, Naomi Ghebremichael
Efforts to control the global malaria health crisis are undermined by antimalarial resistance. Iden-tifying mechanisms of resistance will uncover the underlying biology of the Plasmodium falciparum malaria parasites that allow evasion of our most pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dfe0fbfefd3e52556a0eb1fc197b18da
https://doi.org/10.1101/2021.11.05.467329
https://doi.org/10.1101/2021.11.05.467329