Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Andrew J Humberstone"'
Autor:
James S McCarthy, Silvana Sekuloski, Paul M Griffin, Suzanne Elliott, Nanette Douglas, Chris Peatey, Rebecca Rockett, Peter O'Rourke, Louise Marquart, Cornelius Hermsen, Stephan Duparc, Jörg Möhrle, Katharine R Trenholme, Andrew J Humberstone
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e21914 (2011)
Critical to the development of new drugs for treatment of malaria is the capacity to safely evaluate their activity in human subjects. The approach that has been most commonly used is testing in subjects with natural malaria infection, a methodology
Externí odkaz:
https://doaj.org/article/7780e231ec2144a6986559bb50c42e29
Publikováno v:
Clinical Therapeutics. 36:1395-1401
Purpose This study compared the pharmacokinetics of a single dose of 1% testosterone solution after application to the inner arm or the axilla as application sites for transdermal testosterone therapy. Methods Healthy, not pregnant, premenopausal wom
Publikováno v:
Journal of Pharmaceutical Sciences. 87:936-942
The oral bioavailability of halofantrine (Hf), a highly lipophilic phenanthrenemethanol antimalarial, is significantly enhanced when ingested with food. Although food enhances the absorption of Hf, it also alters the intrinsic pharmacokinetics of Hf
Autor:
Glenn A. Edwards, Shui-Mei Khoo, Christopher J.H. Porter, Andrew J. Humberstone, William N. Charman
Publikováno v:
Monash University
The potential for lipidic self-emulsifying drug delivery systems (SEDDS) and self-microemulsifying drug delivery systems (SMEDDS) to improve the oral bioavailability of a poorly absorbed, antimalarial drug (Halofantrine, Hf) was investigated in faste
Publikováno v:
Advanced Drug Delivery Reviews. 25:103-128
The use of natural and synthetic lipids has generated much academic and commercial interest as a potential formulation strategy for improving the oral bioavailability of poorly water soluble drugs. Lipid-based formulations can reduce the inherent lim
Autor:
Kris Jamsen, Julie A. Simpson, Kate A. Smith, Susan A. Charman, Sophie Zaloumis, Javier Gamo-Benito, Andrew J. Humberstone, Ric N. Price, James M. McCaw, Joerg J. Moehrle
Publikováno v:
Malaria Journal
Malaria Journal, Vol 11, Iss 1, p 303 (2012)
Malaria Journal, Vol 11, Iss 1, p 303 (2012)
Background Mechanistic within-host models relating blood anti-malarial drug concentrations with the parasite-time profile help in assessing dosing schedules and partner drugs for new anti-malarial treatments. A comprehensive simulation study to asses
Autor:
Jörg J. Möhrle, Christopher L. Peatey, Cornelius Hermsen, James S. McCarthy, Paul M. Griffin, Nanette Douglas, Andrew J. Humberstone, Stephan Duparc, Katharine R. Trenholme, Louise Marquart, Silvana Sekuloski, Rebecca Rockett, Peter O'Rourke, Suzanne L. Elliott
Publikováno v:
PLoS One, 6
PLoS ONE, Vol 6, Iss 8, p e21914 (2011)
PLoS ONE
PLoS One, 6, 8
PLoS ONE, Vol 6, Iss 8, p e21914 (2011)
PLoS ONE
PLoS One, 6, 8
Contains fulltext : 95588.pdf (Publisher’s version ) (Open Access) BACKGROUND: Critical to the development of new drugs for treatment of malaria is the capacity to safely evaluate their activity in human subjects. The approach that has been most co
Publikováno v:
Pharmaceutical Research. :1219-1223
Autor:
Robert J. Norman, Mary-Anne Papalia, Sheila O'Neill, John Wlodarczyk, Andrew J Humberstone, Bronwyn G. A. Stuckey, Margaret Redelman, Susan R. Davis, Karen Lee Gard'ner, Margaret Williamson
Publikováno v:
Scopus-Elsevier
University of Western Australia
Monash University
University of Western Australia
Monash University
It is not known whether premenopausal women who report low sexual satisfaction and have low circulating testosterone levels will benefit from testosterone therapy.To evaluate the effects of exogenous testosterone in premenopausal women reporting dimi
Autor:
Regine Sitruk-Ware, Narender Kumar, Louise McCrossin, Yun-Yen Tsong, Ian S. Fraser, S. Kumar, Andrew J. Humberstone, Deborah Shaw, Edith Weisberg
Background Transdermal delivery of steroids is gaining popularity for contraception and hormone replacement therapy. This study aimed to test metered spray delivery of a precise dosage of Nestorone® (NES) progestogen as a possible transdermal proges
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55f10cafad3086c74818a53ac352c372
https://hdl.handle.net/1959.8/49243
https://hdl.handle.net/1959.8/49243