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of 12
pro vyhledávání: '"Andrew J Hirning"'
Autor:
Alan Veliz-Cuba, Andrew J Hirning, Adam A Atanas, Faiza Hussain, Flavia Vancia, Krešimir Josić, Matthew R Bennett
Publikováno v:
PLoS Computational Biology, Vol 11, Iss 12, p e1004674 (2015)
Synthetic gene oscillators are small, engineered genetic circuits that produce periodic variations in target protein expression. Like other gene circuits, synthetic gene oscillators are noisy and exhibit fluctuations in amplitude and period. Understa
Externí odkaz:
https://doaj.org/article/d488803f994b4677a60985eda0d0a322
Autor:
Ramya Ganiga Prabhakar, Gaoyang Fan, Razan N. Alnahhas, Andrew J. Hirning, Matthew R. Bennett, Yousif Shamoo
Publikováno v:
ACS Synthetic Biology. 12:1239-1251
Spatial structure within microbial communities can provide nearly limitless opportunities for social interactions and are an important driver for evolution. As metabolites are often molecular signals, metabolite diffusion within microbial communities
Autor:
David M. Zong, Mehdi Sadeghpour, Sara Molinari, Razan N. Alnahhas, Andrew J. Hirning, Charilaos Giannitsis, William Ott, Krešimir Josić, Matthew R. Bennett
A major challenge in synthetic biology is the manipulation of engineered gene circuits toward a specified behavior. This challenge becomes more difficult as synthetic systems become more complex by incorporating additional genes or strains. Here we d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12e2f6199e17a7587c729fb6a490c089
https://doi.org/10.1101/2022.09.23.509237
https://doi.org/10.1101/2022.09.23.509237
Publikováno v:
ACS Synthetic Biology. 6:1996-2002
Transcription factors and their target promoters are central to synthetic biology. By arranging these components into novel gene regulatory circuits, synthetic biologists have been able to create a wide variety of phenotypes, including bistable switc
Autor:
Andrew J. Hirning, Matthew R. Bennett, William Ott, Bhargav Karamched, James J. Winkle, Krešimir Josić, Razan N. Alnahhas
Publikováno v:
ACS Synth Biol
Synthetic microbial consortia consist of two or more engineered strains that grow together and share the same resources. When intercellular signaling pathways are included in the engineered strains, close proximity of the microbes can generate comple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::119c6c1f783161c1e4c18405ba2ae000
https://doi.org/10.1101/590505
https://doi.org/10.1101/590505
Autor:
Jae Kyoung Kim, Razan N. Alnahhas, Andrew J. Hirning, Matthew R. Bennett, Ye Chen, Krešimir Josić
Publikováno v:
Nature chemical biology
Synthetic microbial consortia have an advantage over isogenic synthetic microbes because they can apportion biochemical and regulatory tasks among the strains. However, it is difficult to coordinate gene expression in spatially extended consortia bec
Publikováno v:
Science. 349:986-989
Engineering cell population behavior Attaining the full promise of synthetic biology will require designing population-level behaviors of multiple interacting cell types. As a start, Chen et al. engineered two strains of the bacterium Escherichia col
Autor:
Faiza Hussain, Kathleen S. Matthews, William Ott, Chinmaya Gupta, Matthew R. Bennett, Krešimir Josić, Andrew J. Hirning
Publikováno v:
Proceedings of the National Academy of Sciences. 111:972-977
Synthetic biology promises to revolutionize biotechnology by providing the means to reengineer and reprogram cellular regulatory mechanisms. However, synthetic gene circuits are often unreliable, as changes to environmental conditions can fundamental
Autor:
Adam A. Atanas, Flavia Vancia, Andrew J. Hirning, Matthew R. Bennett, Alan Veliz-Cuba, Krešimir Josić, Faiza Hussain
Publikováno v:
PLoS Computational Biology
PLoS Computational Biology, Vol 11, Iss 12, p e1004674 (2015)
PLoS Computational Biology, Vol 11, Iss 12, p e1004674 (2015)
Synthetic gene oscillators are small, engineered genetic circuits that produce periodic variations in target protein expression. Like other gene circuits, synthetic gene oscillators are noisy and exhibit fluctuations in amplitude and period. Understa
Autor:
Gabriele Canzi, Chris Bigley, Joyce Lee, Lambert A. Doezema, Andrew J. Hirning, Kylee Chang, Nick Von der Ahe
Publikováno v:
Atmospheric Environment. 44:900-908
The effect of sampling protocol on ambient air hydrocarbon mixing ratios was examined on eight sampling days in Los Angeles during 2007 and 2008. Four protocols, which were based on previously published multi-city urban hydrocarbon studies in the Uni