Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Andrew J Hapel"'
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e95208 (2014)
Unraveling the mechanisms of hematopoiesis regulated by multiple cytokines remains a challenge in hematology. IL-3 is an allergic cytokine with the multilineage potential, while CSF-1 is produced in the steady state with restricted lineage coverage.
Externí odkaz:
https://doaj.org/article/c7d6ec5110504ff19db65bb90cd21132
Publikováno v:
Biomedicines, Vol 11, Iss 9, p 2394 (2023)
Neuroinflammation may be a pathogenic mediator and biomarker of neurodegeneration at the boundary between mild cognitive impairment (MCI) and early-stage Alzheimer’s disease (AD). Whether neuroinflammatory processes are endogenous to the central ne
Externí odkaz:
https://doaj.org/article/4b2c490ac7e7497e82df6b4411c4f6fe
Publikováno v:
Journal of Clinical and Experimental Hematopathology. 53:115-120
4) Myb-transformed haematopoietic cell (MTHC) lines have been developed and clones selected based on their ability to respond to tumor necrosis factor (TNF)-a. MTHC-A cells underwent apoptosis in response to TNF-a (MTHC-A). The apoptotic effect of TN
Autor:
Nicholas H R Hamilton, Alistair J. Ramsay, Surendran Mahalingam, Ian A. Ramshaw, Scott Thomson, Joanne Banyer, Andrew J. Hapel
Publikováno v:
Scandinavian Journal of Immunology. 55:53-60
Murine interferon-inducible T cell alpha chemokine (I-TAC) is a potent non-ELR Cys-X-Cys (CXC) chemokine that predominantly attracts activated T lymphocytes and binds to the receptor CXCR3. Using semiquantitative reverse transcription–polymerase ch
Autor:
David A. Mann, Ian G. Young, Michelle J. Townsend, C. F. Morris, Andrew J. Hapel, Ming Chiu Fung, J. Dennis Wilson, Charmaine J. Simeonovic
Publikováno v:
Transplantation. 67:963-971
Background. Previous in vivo depletion studies of CD4 and CD8 T cells indicated that different rejection mechanisms operate for proislet allografts and xenografts. The cellular and molecular mechanisms of acute proislet allograft and xenograft reject
Autor:
Maheshi Prabodani Obeysekera, Adam Taylor, Andrew Zakhary, Suresh Mahalingam, Kuo-Ching Sheng, Lara J. Herrero, Michelle Nelson, Stefan Wolf, Michelle E. Gahan, Belinda L. Herring, Shobha Broor, Jayaram Bettadapura, Andrew J. Hapel, Paul A. Keller, Lalit Dar, Weiqiang Chen
Publikováno v:
Pharmacologytherapeutics. 137(2)
Dengue virus (DV) is the most widespread arbovirus, being endemic in over 100 countries, and is estimated to cause 50 million infections annually. Viral factors, such as the genetic composition of the virus strain can play a role in determining the v
Autor:
Andrew J. Hapel, Stephen J. Galli, George F.J. Newlands, Donna R. Cohen, Raj Sangha, Lesley Inglis, David M. Haig, John F. Huntley, A. Mackellar, Hugh R. P. Miller
Publikováno v:
Blood. 83:72-83
The effects of rat stem-cell factor (SCF) and interleukin-3 (IL-3), alone or in combination, on the in vitro growth and serine proteinase expression of rat serosal/connective-tissue mast cells (CTMC) or bone marrow-derived mast cells (BMMC) were exam
Publikováno v:
IUBMB Life (International Union of Biochemistry and Molecular Biology: Life). 54:305-307
Publikováno v:
Blood. 82:2813-2822
Murine hematopoietic cells can be transformed in vitro by recombinant retroviruses that express the myb oncogene, and hematopoietic growth factor (HGF)-dependent myeloid cell lines can be derived from these transformed primary cells. In this study, t
Publikováno v:
British Journal of Haematology. 82:488-493
Summary. Haemopoietic cells from A/J mice do not form colonies (proliferate) in response to interleukin-3 (multi-CSF. IL-3). We have examined different populations of cells from A/J mice and shown that, despite their failure to proliferate in respons