Zobrazeno 1 - 10
of 191
pro vyhledávání: '"Andrew J Ewald"'
Publikováno v:
PLoS Computational Biology, Vol 20, Iss 6, p e1012195 (2024)
Therapeutic interventions are designed to perturb the function of a biological system. However, there are many types of proteins that cannot be targeted with conventional small molecule drugs. Accordingly, many identified gene-regulatory drivers and
Externí odkaz:
https://doaj.org/article/02ea3ba2e69f4ad4996c9faec1975b45
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 1, p e1007464 (2020)
For women with access to healthcare and early detection, breast cancer deaths are caused primarily by metastasis rather than growth of the primary tumor. Metastasis has been difficult to study because it happens deep in the body, occurs over years, a
Externí odkaz:
https://doaj.org/article/12dd0af4abf94080b7a0990fad6da970
Autor:
Elodie Henriet, Hildur Knutsdottir, Eloise M. Grasset, Matthew Dunworth, Meagan Haynes, Joel S. Bader, Andrew J. Ewald
Publikováno v:
Oncogene. 42:737-747
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::998608b649193e26e188cc6059047593
https://doi.org/10.1038/s41388-022-02586-2
https://doi.org/10.1038/s41388-022-02586-2
Autor:
Geonhui Lee, Claudia Wong, Anna Cho, Junior J. West, Ashleigh J. Crawford, Gabriella C. Russo, Bishwa Ranjan Si, Jungwoo Kim, Lauren Hoffner, Cholsoon Jang, Moonjung Jung, Robert D. Leone, Konstantinos Konstantopoulos, Andrew J. Ewald, Denis Wirtz, Sangmoo Jeong
Publikováno v:
bioRxiv
The loss of E-cadherin (E-cad), an epithelial cell adhesion molecule, has been implicated in the epithelial-mesenchymal transition (EMT), promoting invasion and migration of cancer cells and, consequently, metastasis. However, recent studies have dem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22fc88719f8686b1892099ccf3116d15
https://europepmc.org/articles/PMC10245808/
https://europepmc.org/articles/PMC10245808/
Autor:
Yea Ji Jeong, Hildur Knutsdottir, Fatemeh Shojaeian, Michael G. Lerner, Maria F. Wissler, Elodie Henriet, Tammy Ng, Shalini Datta, Bernat Navarro-Serer, Peter Chianchiano, Benedict Kinny-Köster, Jacquelyn W. Zimmerman, Genevieve Stein-O’Brien, Matthias M. Gaida, James R. Eshleman, Ming-Tseh Lin, Elana J. Fertig, Andrew J. Ewald, Joel S. Bader, Laura D. Wood
Publikováno v:
Journal of Clinical Investigation. 133
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f07836e6009a008def57778666a4a89
https://doi.org/10.1172/jci162054
https://doi.org/10.1172/jci162054
Autor:
Andrew J. Ewald, Gareth J. Thomas, Orit Katarina Sirka, Elodie Henriet, Christopher J. Hanley
Supplementary Materials and Methods. Figure S1. Weighted gene correlation network analysis of RNA-Sequencing from human invasive ductal breast cancer primary tumor samples.Figure S2: Physical interaction between stromal cells and invasive organoids.F
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e0319f79db58113c12ed2728f890bb6
https://doi.org/10.1158/1541-7786.22525823
https://doi.org/10.1158/1541-7786.22525823
Autor:
Timothy F. Burns, Phuoc T. Tran, Charles M. Rudin, Yoon-Jae Cho, Andrew J. Ewald, Johnathan A. Engh, Ashwin Somasundaram, Katriana Nugent, Sarah N. Chatley, Eric H.-B. Huang, Myriam A. Attar, Hailun Wang, Suman Chatterjee, Susheel K. Khetarpal, Neil M. Neumann, Lucia Mazzacurati, Jessica Cades, Zachary A. Yochum
Supplementary Table 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bfa1b6007ee5e3f0d85bba1531cda94
https://doi.org/10.1158/1541-7786.22516038.v1
https://doi.org/10.1158/1541-7786.22516038.v1
Autor:
Andrew J. Ewald, Gareth J. Thomas, Orit Katarina Sirka, Elodie Henriet, Christopher J. Hanley
Collective invasion can be led by breast cancer cells expressing basal epithelial markers, typified by keratin-14 (KRT14). We analyzed gene expression data from The Cancer Genome Atlas and demonstrated a significant correlation between a KRT14+ invas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30d7f15cdf23b158c4bb7224a9382bb2
https://doi.org/10.1158/1541-7786.c.6544919
https://doi.org/10.1158/1541-7786.c.6544919
Autor:
Andrew J. Ewald, Gareth J. Thomas, Orit Katarina Sirka, Elodie Henriet, Christopher J. Hanley
Breast cancer subtype specific WGCN analysis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::780c246e15ad4765606355e589ebdf67
https://doi.org/10.1158/1541-7786.22525820
https://doi.org/10.1158/1541-7786.22525820
Autor:
Timothy F. Burns, Phuoc T. Tran, Charles M. Rudin, Yoon-Jae Cho, Andrew J. Ewald, Johnathan A. Engh, Ashwin Somasundaram, Katriana Nugent, Sarah N. Chatley, Eric H.-B. Huang, Myriam A. Attar, Hailun Wang, Suman Chatterjee, Susheel K. Khetarpal, Neil M. Neumann, Lucia Mazzacurati, Jessica Cades, Zachary A. Yochum
Supplementary Figure 1: FGF2 treatment induces branching morphogenesis of primary epithelial cells in 3D culture. Supplementary Figure 2: Basal Expression Levels of TWIST1 in KRAS mutant and MET Amplified/Mutant NSCLC Cell Lines. Supplementary Figure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1f1097e57873a7c17b1f52cb23486f8
https://doi.org/10.1158/1541-7786.22516041.v1
https://doi.org/10.1158/1541-7786.22516041.v1