Zobrazeno 1 - 10
of 412
pro vyhledávání: '"Andrew J Davison"'
Autor:
Michael L Wood, Colin D Veal, Rita Neumann, Nicolás M Suárez, Jenna Nichols, Andrei J Parker, Diana Martin, Simon PR Romaine, Veryan Codd, Nilesh J Samani, Adriaan A Voors, Maciej Tomaszewski, Louis Flamand, Andrew J Davison, Nicola J Royle
Publikováno v:
eLife, Vol 10 (2021)
Human herpesviruses 6A and 6B (HHV-6A/6B) are ubiquitous pathogens that persist lifelong in latent form and can cause severe conditions upon reactivation. They are spread by community-acquired infection of free virus (acqHHV6A/6B) and by germline tra
Externí odkaz:
https://doaj.org/article/739e0ec094364dfd9c2de17914d4c097
Autor:
Emilia A H Vanni, Joseph W Foley, Andrew J Davison, Marvin Sommer, Dongmei Liu, Phillip Sung, Jennifer Moffat, Leigh Zerboni, Ann M Arvin
Publikováno v:
PLoS Pathogens, Vol 16, Iss 12, p e1009166 (2020)
Herpes simplex virus 1 (HSV-1) infects skin and mucosal epithelial cells and then travels along axons to establish latency in the neurones of sensory ganglia. Although viral gene expression is restricted during latency, the latency-associated transcr
Externí odkaz:
https://doaj.org/article/4837bd804ca54bc4b614cfe9b39aa1fc
Autor:
Julie Tai-Schmiedel, Sharon Karniely, Betty Lau, Adi Ezra, Erez Eliyahu, Aharon Nachshon, Karen Kerr, Nicolás Suárez, Michal Schwartz, Andrew J Davison, Noam Stern-Ginossar
Publikováno v:
PLoS Pathogens, Vol 16, Iss 4, p e1008390 (2020)
Viruses are known for their extremely compact genomes composed almost entirely of protein-coding genes. Nonetheless, four long noncoding RNAs (lncRNAs) are encoded by human cytomegalovirus (HCMV). Although these RNAs accumulate to high levels during
Externí odkaz:
https://doaj.org/article/0435113fc0764014a407f313d31e4fb6
Autor:
Françoise Myster, Mei-Jiao Gong, Justine Javaux, Nicolás M Suárez, Gavin S Wilkie, Tim Connelley, Alain Vanderplasschen, Andrew J Davison, Benjamin G Dewals
Publikováno v:
PLoS Pathogens, Vol 16, Iss 3, p e1008405 (2020)
Alcelaphine herpesvirus 1 (AlHV-1) is a gammaherpesvirus that is carried asymptomatically by wildebeest. Upon cross-species transmission to other ruminants, including domestic cattle, AlHV-1 induces malignant catarrhal fever (MCF), which is a fatal l
Externí odkaz:
https://doaj.org/article/184f2a4f10cc4944a0da4bf738344e70
Autor:
Luis V Nobre, Katie Nightingale, Benjamin J Ravenhill, Robin Antrobus, Lior Soday, Jenna Nichols, James A Davies, Sepehr Seirafian, Eddie CY Wang, Andrew J Davison, Gavin WG Wilkinson, Richard J Stanton, Edward L Huttlin, Michael P Weekes
Publikováno v:
eLife, Vol 8 (2019)
Human cytomegalovirus (HCMV) extensively modulates host cells, downregulating >900 human proteins during viral replication and degrading ≥133 proteins shortly after infection. The mechanism of degradation of most host proteins remains unresolved, a
Externí odkaz:
https://doaj.org/article/d9cf04ffe19c4d6392dcfe47e0a4c2a3
Autor:
Dan F Young, Elizabeth B Wignall-Fleming, David C Busse, Matthew J Pickin, Jack Hankinson, Elizabeth M Randall, Amy Tavendale, Andrew J Davison, Douglas Lamont, John S Tregoning, Steve Goodbourn, Richard E Randall
Publikováno v:
PLoS Pathogens, Vol 15, Iss 2, p e1007561 (2019)
Paramyxoviruses can establish persistent infections both in vitro and in vivo, some of which lead to chronic disease. However, little is known about the molecular events that contribute to the establishment of persistent infections by RNA viruses. Us
Externí odkaz:
https://doaj.org/article/a23a3a3339e44b22990637cb0bd641e7
Autor:
Marie Garvey, Nicolás M Suárez, Karen Kerr, Ralph Hector, Laura Moloney-Quinn, Sean Arkins, Andrew J Davison, Ann Cullinane
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0192301 (2018)
Equid herpesvirus 8 (EHV-8), formerly known as asinine herpesvirus 3, is an alphaherpesvirus that is closely related to equid herpesviruses 1 and 9 (EHV-1 and EHV-9). The pathogenesis of EHV-8 is relatively little studied and to date has only been as
Externí odkaz:
https://doaj.org/article/89dcfd47da42477ebcd6081dd84ff639
Autor:
Ceri A Fielding, Michael P Weekes, Luis V Nobre, Eva Ruckova, Gavin S Wilkie, Joao A Paulo, Chiwen Chang, Nicolás M Suárez, James A Davies, Robin Antrobus, Richard J Stanton, Rebecca J Aicheler, Hester Nichols, Borek Vojtesek, John Trowsdale, Andrew J Davison, Steven P Gygi, Peter Tomasec, Paul J Lehner, Gavin W G Wilkinson
Publikováno v:
eLife, Vol 6 (2017)
The human cytomegalovirus (HCMV) US12 family consists of ten sequentially arranged genes (US12-21) with poorly characterized function. We now identify novel natural killer (NK) cell evasion functions for four members: US12, US14, US18 and US20. Using
Externí odkaz:
https://doaj.org/article/0d101cdaf57c4a5ebf6d46b423b8183c
Autor:
Konstantinos V Papageorgiou, Nicolás M Suárez, Gavin S Wilkie, Michael McDonald, Elizabeth M Graham, Andrew J Davison
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0156015 (2016)
Canine herpesvirus is a widespread alphaherpesvirus that causes a fatal haemorrhagic disease of neonatal puppies. We have used high-throughput methods to determine the genome sequences of three viral strains (0194, V777 and V1154) isolated in the Uni
Externí odkaz:
https://doaj.org/article/d7d72d35413c40c3a2afcdf2a1c68e81
Autor:
Jye-Lin Hsu, Dick J H van den Boomen, Peter Tomasec, Michael P Weekes, Robin Antrobus, Richard J Stanton, Eva Ruckova, Daniel Sugrue, Gavin S Wilkie, Andrew J Davison, Gavin W G Wilkinson, Paul J Lehner
Publikováno v:
PLoS Pathogens, Vol 11, Iss 4, p e1004811 (2015)
Human cytomegalovirus (HCMV) US2, US3, US6 and US11 act in concert to prevent immune recognition of virally infected cells by CD8+ T-lymphocytes through downregulation of MHC class I molecules (MHC-I). Here we show that US2 function goes far beyond M
Externí odkaz:
https://doaj.org/article/d057a00df10f4bbdb235d95e59e2cbce