Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Andrew J Currie"'
Autor:
Elke Seppanen, Dino Tan, Karli J Corscadden, Andrew J Currie, Peter C Richmond, Ruth B Thornton, Lea-Ann S Kirkham
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0193962 (2018)
Otitis media (OM) remains a common paediatric disease, despite advances in vaccinology. Susceptibility to recurrent acute OM (rAOM) has been postulated to involve defective cell-mediated immune responses to common otopathogenic bacteria. We compared
Externí odkaz:
https://doaj.org/article/a7f923c2e81c48e785563c0713b89e51
Autor:
Sofia Sintoris, Justyna M. Binkowska, Jonathan L. Gillan, Roy P. Zuurbier, Jonathan Twynam-Perkins, Maartje Kristensen, Lauren Melrose, Paula Lusaretta Parga, Alicia Ruiz Rodriguez, Mei Ling Chu, Sara R. van Boeckel, Joanne G. Wildenbeest, Dawn M. E. Bowdish, Andrew J. Currie, Ryan S. Thwaites, Jurgen Schwarze, Marlies A. van Houten, James P. Boardman, Steve Cunningham, Debby Bogaert, Donald J. Davidson
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-18 (2024)
Abstract Respiratory syncytial virus is the major cause of acute lower respiratory tract infections in young children, causing extensive mortality and morbidity globally, with limited therapeutic or preventative options. Cathelicidins are innate immu
Externí odkaz:
https://doaj.org/article/7a315c29b5364d6da9023a1485e4aecf
Autor:
Mario Fidanza, Julie Hibbert, Erica Acton, Danny Harbeson, Elizna Schoeman, Patrycja Skut, Tabitha Woodman, Adrien Eynaud, Lucy Hartnell, Byron Brook, Bing Cai, Mandy Lo, Reza Falsafi, Robert E. W. Hancock, Msandeni Chiume-Kayuni, Norman Lufesi, Constantin R. Popescu, Pascal M. Lavoie, Tobias Strunk, Andrew J. Currie, Tobias R. Kollmann, Nelly Amenyogbe, Amy H. Lee
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Neonatal sepsis is a major cause of childhood mortality. Limited diagnostic tools and mechanistic insights have hampered our abilities to develop prophylactic or therapeutic interventions. Biomarkers in human neonatal sepsis have been repeat
Externí odkaz:
https://doaj.org/article/b54f31f4736543a6a2fa9c599d17c04a
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0133126 (2015)
Carrier-specific T cell and polysaccharide-specific B cell memory responses are not well characterised in infants following glyco-conjugate vaccination. We aimed to determine if the number of Meningococcal (Men) C- and Y- specific memory B cells and;
Externí odkaz:
https://doaj.org/article/69ee9a98f36e4c56b1f3ff0ef85c7386
Autor:
Stephanie Trend, Tobias Strunk, Julie Hibbert, Chooi Heen Kok, Guicheng Zhang, Dorota A Doherty, Peter Richmond, David Burgner, Karen Simmer, Donald J Davidson, Andrew J Currie
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0117038 (2015)
OBJECTIVE:We investigated the levels and antimicrobial activity of antimicrobial proteins and peptides (AMPs) in breast milk consumed by preterm infants, and whether deficiencies of these factors were associated with late-onset neonatal sepsis (LOS),
Externí odkaz:
https://doaj.org/article/a6cc5e884db44c7c8389ef589439211f
Autor:
Tobias Strunk, Melanie R Power Coombs, Andrew J Currie, Peter Richmond, Douglas T Golenbock, Liat Stoler-Barak, Leighanne C Gallington, Michael Otto, David Burgner, Ofer Levy
Publikováno v:
PLoS ONE, Vol 5, Iss 4, p e10111 (2010)
Staphylococcus epidermidis (SE) is a nosocomial pathogen that causes catheter-associated bacteremia in the immunocompromised, including those at the extremes of age, motivating study of host clearance mechanisms. SE-derived soluble components engage
Externí odkaz:
https://doaj.org/article/83e1b7bf389445a0aa3ac9f334df3b9b
Autor:
Robbert G van der Most, Andrew J Currie, Amanda L Cleaver, Joanne Salmons, Anna K Nowak, Sathish Mahendran, Irma Larma, Amy Prosser, Bruce W S Robinson, Mark J Smyth, Anthony A Scalzo, Mariapia A Degli-Esposti, Richard A Lake
Publikováno v:
PLoS ONE, Vol 4, Iss 9, p e6982 (2009)
BACKGROUND:Anti-cancer chemotherapy can be simultaneously lymphodepleting and immunostimulatory. Pre-clinical models clearly demonstrate that chemotherapy can synergize with immunotherapy, raising the question how the immune system can be mobilized t
Externí odkaz:
https://doaj.org/article/13dc5af7b53147ddaccffeb6b7996fb7
Autor:
Janet Ferrier, Andrew Chapman, Alisa Higgins, Edward Raby, Laurens Manning, Sam Salman, Bradley Wibrow, Adrian Regli, David Broadhurst, Susan Pellicano, Edward Litton, Anu Rammohan, Jolene Lim, Andrea Paparini, Erina Myers, Bernhard Richter, David Weight, Matthew Anstey, Fiona M. Wood, Sharon Waterson, Joel P. A. Gummer, Tobias Strunk, Andrew J. Currie, Katrina Orr, Anne Marie Palermo
Publikováno v:
Intensive Care Medicine
Purpose In adults requiring treatment in an intensive care unit, probiotic therapy using Lactobacillus plantarum 299v may reduce nosocomial infection. The aim of this study was to determine whether early and sustained L. plantarum 299v therapy admini
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bb96e06e4c859e785add108b93d5e76
http://europepmc.org/articles/PMC7873510
http://europepmc.org/articles/PMC7873510
Autor:
Salome Abbott, Robin J. Green, Siew-Kim Khoo, Joelene Bizzintino, Guicheng Zhang, Peter N. Le Souëf, Andrew J. Currie, Julie Hibbert, Ingrid A. Laing, Alicia A. Annamalay
Publikováno v:
Journal of Medical Virology. 93:3647-3655
Altered host immune responses are considered to play a key role in the pathogenesis of acute lower respiratory infections (ALRI). The existing literature on cytokine responses in ALRI is largely focussed on adults from developed countries and there a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80e6d00c895bffe382fcd5e0f9d63356
https://doi.org/10.1002/jmv.26730
https://doi.org/10.1002/jmv.26730
Autor:
David Burgner, Caitlyn Granland, Sherrianne Ng, Nicola J. Armstrong, Peter Richmond, Tobias Strunk, Andrew J. Currie, Julie Hibbert, Karen Simmer
Publikováno v:
Acta Paediatrica. 110:3011-3013
Preterm infants are particularly susceptible to bacterial late-onset sepsis (LOS). Diagnosis by blood culture and inflammatory markers have sub-optimal sensitivity and specificity and prolonged reporting times. There is an urgent need for more rapid,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::725e5f7b5d3c9b74049a1ddcd3597984
https://doi.org/10.1111/apa.15969
https://doi.org/10.1111/apa.15969