Zobrazeno 1 - 10
of 138
pro vyhledávání: '"Andrew J Currie"'
Autor:
Sofia Sintoris, Justyna M. Binkowska, Jonathan L. Gillan, Roy P. Zuurbier, Jonathan Twynam-Perkins, Maartje Kristensen, Lauren Melrose, Paula Lusaretta Parga, Alicia Ruiz Rodriguez, Mei Ling Chu, Sara R. van Boeckel, Joanne G. Wildenbeest, Dawn M. E. Bowdish, Andrew J. Currie, Ryan S. Thwaites, Jurgen Schwarze, Marlies A. van Houten, James P. Boardman, Steve Cunningham, Debby Bogaert, Donald J. Davidson
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-18 (2024)
Abstract Respiratory syncytial virus is the major cause of acute lower respiratory tract infections in young children, causing extensive mortality and morbidity globally, with limited therapeutic or preventative options. Cathelicidins are innate immu
Externí odkaz:
https://doaj.org/article/7a315c29b5364d6da9023a1485e4aecf
Autor:
Mario Fidanza, Julie Hibbert, Erica Acton, Danny Harbeson, Elizna Schoeman, Patrycja Skut, Tabitha Woodman, Adrien Eynaud, Lucy Hartnell, Byron Brook, Bing Cai, Mandy Lo, Reza Falsafi, Robert E. W. Hancock, Msandeni Chiume-Kayuni, Norman Lufesi, Constantin R. Popescu, Pascal M. Lavoie, Tobias Strunk, Andrew J. Currie, Tobias R. Kollmann, Nelly Amenyogbe, Amy H. Lee
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Neonatal sepsis is a major cause of childhood mortality. Limited diagnostic tools and mechanistic insights have hampered our abilities to develop prophylactic or therapeutic interventions. Biomarkers in human neonatal sepsis have been repeat
Externí odkaz:
https://doaj.org/article/b54f31f4736543a6a2fa9c599d17c04a
Publikováno v:
Journal of Functional Foods, Vol 57, Iss , Pp 182-189 (2019)
Colostrum contains bioactive components protecting the newborn intestine against bacteria. It is unclear how to optimize processing conditions with highest product bioactivity. Non-pasteurized (BC00), standard-pasteurized (72 °C-15 s, BC72), gently-
Externí odkaz:
https://doaj.org/article/c19db6941fac45daaaa8443c58cd2a23
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/913e64c21b0a40c38b76b4a42742bcf5
Autor:
Cibele M. Gaido, Caitlyn Granland, Ingrid A. Laing, Peter N. Le Souëf, Wayne R. Thomas, Andrew J. Currie, Belinda J. Hales
Publikováno v:
Immunity, Inflammation and Disease, Vol 6, Iss 1, Pp 143-153 (2018)
Abstract Background Infections by rhinovirus (RV) species A and C are the most common causes of exacerbations of asthma and a major cause of exacerbations of other acute and chronic respiratory diseases. Infections by both species are prevalent in pr
Externí odkaz:
https://doaj.org/article/ea807343aa7f4d90920f7082bf9e9e86
Autor:
Emily Gwyer Findlay, Andrew J. Currie, Ailiang Zhang, Jana Ovciarikova, Lisa Young, Holly Stevens, Brian J. McHugh, Marta Canel, Mohini Gray, Simon W.F. Milling, John D.M. Campbell, John Savill, Alan Serrels, Donald J. Davidson
Publikováno v:
OncoImmunology, Vol 8, Iss 8 (2019)
Immunization of patients with autologous, ex vivo matured dendritic cell (DC) preparations, in order to prime antitumor T-cell responses, is the focus of intense research. Despite progress and approval of clinical approaches, significant enhancement
Externí odkaz:
https://doaj.org/article/8c619a0ba3fa49a6a60740bf5be1c638
Autor:
Elke Seppanen, Dino Tan, Karli J Corscadden, Andrew J Currie, Peter C Richmond, Ruth B Thornton, Lea-Ann S Kirkham
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0193962 (2018)
Otitis media (OM) remains a common paediatric disease, despite advances in vaccinology. Susceptibility to recurrent acute OM (rAOM) has been postulated to involve defective cell-mediated immune responses to common otopathogenic bacteria. We compared
Externí odkaz:
https://doaj.org/article/a7f923c2e81c48e785563c0713b89e51
Autor:
Janet Ferrier, Andrew Chapman, Alisa Higgins, Edward Raby, Laurens Manning, Sam Salman, Bradley Wibrow, Adrian Regli, David Broadhurst, Susan Pellicano, Edward Litton, Anu Rammohan, Jolene Lim, Andrea Paparini, Erina Myers, Bernhard Richter, David Weight, Matthew Anstey, Fiona M. Wood, Sharon Waterson, Joel P. A. Gummer, Tobias Strunk, Andrew J. Currie, Katrina Orr, Anne Marie Palermo
Publikováno v:
Intensive Care Medicine
Purpose In adults requiring treatment in an intensive care unit, probiotic therapy using Lactobacillus plantarum 299v may reduce nosocomial infection. The aim of this study was to determine whether early and sustained L. plantarum 299v therapy admini
Autor:
Salome Abbott, Robin J. Green, Siew-Kim Khoo, Joelene Bizzintino, Guicheng Zhang, Peter N. Le Souëf, Andrew J. Currie, Julie Hibbert, Ingrid A. Laing, Alicia A. Annamalay
Publikováno v:
Journal of Medical Virology. 93:3647-3655
Altered host immune responses are considered to play a key role in the pathogenesis of acute lower respiratory infections (ALRI). The existing literature on cytokine responses in ALRI is largely focussed on adults from developed countries and there a
Autor:
David Burgner, Caitlyn Granland, Sherrianne Ng, Nicola J. Armstrong, Peter Richmond, Tobias Strunk, Andrew J. Currie, Julie Hibbert, Karen Simmer
Publikováno v:
Acta Paediatrica. 110:3011-3013
Preterm infants are particularly susceptible to bacterial late-onset sepsis (LOS). Diagnosis by blood culture and inflammatory markers have sub-optimal sensitivity and specificity and prolonged reporting times. There is an urgent need for more rapid,