Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Andrew J Bruening"'
Autor:
Jinming Gao, David A. Boothman, Meghan Beman, Andrew J Bruening, Andy F. Wiedmann, Norased Nasongkla, Dale Ray, William Bornmann
Publikováno v:
Pharmaceutical Research. 20:1626-1633
Purpose. To explore the use of cyclodextrins (CD) to form inclusion complexes with β-lapachone (β-lap) to overcome solubility and bioavailability problems previously noted with this drug.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9fde9a6e96f3b5b93e4c62aaea08bf22
https://doi.org/10.1023/a:1026143519395
https://doi.org/10.1023/a:1026143519395
Autor:
Mark W. Wagner, David A. Boothman, Andrew J Bruening, W. David Sedwick, Mark Meyers, Martina L. Veigl, Arlene Hwang
Publikováno v:
Oncogene. 22(47)
The phenomenon of damage tolerance, whereby cells incur DNA lesions that are nonlethal, largely ignored, but highly mutagenic, appears to play a key role in carcinogenesis. Typically, these lesions are generated by alkylation of DNA or incorporation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a20a4e51f9083de0046f8a18ac93dddd
https://pubmed.ncbi.nlm.nih.gov/14576845
https://pubmed.ncbi.nlm.nih.gov/14576845