Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Andrew J, Olive"'
Autor:
Corinna A. Kulicke, Gwendolyn M. Swarbrick, Nicole A. Ladd, Meghan Cansler, Megan Null, Aneta Worley, Chance Lemon, Tania Ahmed, Joshua Bennett, Taylor N. Lust, Chelsea M. Heisler, Megan E. Huber, Jason R. Krawic, Laurisa M. Ankley, Savannah K. McBride, Fikadu G. Tafesse, Andrew J. Olive, William H. Hildebrand, Deborah A. Lewinsohn, Erin J. Adams, David M. Lewinsohn, Melanie J. Harriff
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-13 (2024)
Abstract MR1-restricted T cells have been implicated in microbial infections, sterile inflammation, wound healing and cancer. Similar to other antigen presentation molecules, evidence supports multiple, complementary MR1 antigen presentation pathways
Externí odkaz:
https://doaj.org/article/a188a5d473ac493d8d7f9aa7fe4c7e44
Autor:
Olivia K. Favor, Lichchavi D. Rajasinghe, Kathryn A. Wierenga, Krishna R. Maddipati, Kin Sing Stephen Lee, Andrew J. Olive, James J. Pestka
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionPhagocytosis of inhaled crystalline silica (cSiO2) particles by tissue-resident alveolar macrophages (AMs) initiates generation of proinflammatory eicosanoids derived from the ω-6 polyunsaturated fatty acid (PUFA) arachidonic acid (ARA)
Externí odkaz:
https://doaj.org/article/c5241d8c3bfb4c839104b3a15452ac10
Autor:
John T. Williams, Jacob J. Baker, Huiqing Zheng, Shelby J. Dechow, Jared Fallon, Megan Murto, Veronica J. Albrecht, Haleigh N. Gilliland, Andrew J. Olive, Robert B. Abramovitch
Publikováno v:
mSphere, Vol 8, Iss 5 (2023)
ABSTRACT Mycobacteria can colonize environments where the availability of metal ions is limited. Biological or inorganic chelators play an important role in limiting metal availability, and we developed a model to examine Mycobacterium smegmatis surv
Externí odkaz:
https://doaj.org/article/de6e211fa6394e21a1a6d66507766a86
Autor:
Rochelle C Glover, Nicole H Schwardt, Shania-Kate E Leano, Madison E Sanchez, Maureen K Thomason, Andrew J Olive, Michelle L Reniere
Publikováno v:
PLoS Pathogens, Vol 19, Iss 5, p e1011058 (2023)
Listeria monocytogenes (Lm) is an intracellular foodborne pathogen which causes the severe disease listeriosis in immunocompromised individuals. Macrophages play a dual role during Lm infection by both promoting dissemination of Lm from the gastroint
Externí odkaz:
https://doaj.org/article/2607f0afcdfb4f06952be31403f76c93
Publikováno v:
mSphere, Vol 8, Iss 2 (2023)
ABSTRACT The interactions between a host cell and a pathogen can dictate disease outcomes and are important targets for host-directed therapies. Mycobacterium abscessus (Mab) is a highly antibiotic resistant, rapidly growing nontuberculous mycobacter
Externí odkaz:
https://doaj.org/article/ac566f7217904cc99a6fdb1a57c009a3
Autor:
Clare M Smith, Richard E Baker, Megan K Proulx, Bibhuti B Mishra, Jarukit E Long, Sae Woong Park, Ha-Na Lee, Michael C Kiritsy, Michelle M Bellerose, Andrew J Olive, Kenan C Murphy, Kadamba Papavinasasundaram, Frederick J Boehm, Charlotte J Reames, Rachel K Meade, Brea K Hampton, Colton L Linnertz, Ginger D Shaw, Pablo Hock, Timothy A Bell, Sabine Ehrt, Dirk Schnappinger, Fernando Pardo-Manuel de Villena, Martin T Ferris, Thomas R Ioerger, Christopher M Sassetti
Publikováno v:
eLife, Vol 11 (2022)
The outcome of an encounter with Mycobacterium tuberculosis (Mtb) depends on the pathogen’s ability to adapt to the variable immune pressures exerted by the host. Understanding this interplay has proven difficult, largely because experimentally tra
Externí odkaz:
https://doaj.org/article/22a97844641345f9a6ecfdcfcd9e9300
Autor:
Michael C Kiritsy, Laurisa M Ankley, Justin Trombley, Gabrielle P Huizinga, Audrey E Lord, Pontus Orning, Roland Elling, Katherine A Fitzgerald, Andrew J Olive
Publikováno v:
eLife, Vol 10 (2021)
Cytokine-mediated activation of host immunity is central to the control of pathogens. Interferon-gamma (IFNγ) is a key cytokine in protective immunity that induces major histocompatibility complex class II molecules (MHCII) to amplify CD4+ T cell ac
Externí odkaz:
https://doaj.org/article/27cb52ae4b22483f922ca3e06412e9cd
Autor:
Michael C Kiritsy, Katelyn McCann, Daniel Mott, Steven M Holland, Samuel M Behar, Christopher M Sassetti, Andrew J Olive
Publikováno v:
eLife, Vol 10 (2021)
The immunological synapse allows antigen-presenting cells (APCs) to convey a wide array of functionally distinct signals to T cells, which ultimately shape the immune response. The relative effect of stimulatory and inhibitory signals is influenced b
Externí odkaz:
https://doaj.org/article/fad7299fdf484cf5967a11a43468f79a
Autor:
Yi Cai, Eleni Jaecklein, Jared S Mackenzie, Kadamba Papavinasasundaram, Andrew J Olive, Xinchun Chen, Adrie J C Steyn, Christopher M Sassetti
Publikováno v:
PLoS Pathogens, Vol 17, Iss 7, p e1008911 (2021)
In order to sustain a persistent infection, Mycobacterium tuberculosis (Mtb) must adapt to a changing environment that is shaped by the developing immune response. This necessity to adapt is evident in the flexibility of many aspects of Mtb metabolis
Externí odkaz:
https://doaj.org/article/78c80d612a13471299af88d25e1f2703
Autor:
Andrew J. Olive
Publikováno v:
mSphere, Vol 5, Iss 1 (2020)
ABSTRACT Andrew J. Olive works in the field of host responses to chronic infections. In this mSphere of Influence article, he reflects on how “Tryptophan biosynthesis protects mycobacteria from CD4 T-cell-mediated killing” (Y. J. Zhang, M. C. Red
Externí odkaz:
https://doaj.org/article/442aca41a1e34a45aa79801956426af5