Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Andrew J, Miles"'
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-8 (2023)
Abstract Intrinsically disordered proteins (IDPs) are comprised of significant numbers of residues that form neither helix, sheet, nor any other canonical type of secondary structure. They play important roles in a broad range of biological processes
Externí odkaz:
https://doaj.org/article/4ae69c8c477844c19f71d12f3121455f
Autor:
Nazzareno D’Avanzo, Andrew J. Miles, Andrew M. Powl, Colin G. Nichols, B.A. Wallace, Andrias O. O’Reilly
Cytoplasmic domains frequently promote functional assembly of multimeric ion channels. To investigate structural determinants of this process, we generated the ‘T1-chimera’ construct of the NaChBac sodium channel by truncating the C-terminal doma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fc8b2d072f6f972ab0f8f04984a2bc4
https://eprints.bbk.ac.uk/id/eprint/47007/8/47007a.pdf
https://eprints.bbk.ac.uk/id/eprint/47007/8/47007a.pdf
Autor:
Nazzareno D'Avanzo, Emily C McCusker, Andrew M Powl, Andrew J Miles, Colin G Nichols, B A Wallace
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e61216 (2013)
The lipid bilayer is important for maintaining the integrity of cellular compartments and plays a vital role in providing the hydrophobic and charged interactions necessary for membrane protein structure, conformational flexibility and function. To d
Externí odkaz:
https://doaj.org/article/c7a1618d6fb14c50a604b18925695d3e
Autor:
Andrew J. Miles, Bonnie A. Wallace
Publikováno v:
Protein Science. 27:1717-1722
Circular dichroism (CD) spectroscopy is a highly used method for the examination and characterization of proteins, including, amongst other features, their secondary and tertiary structures, thermal stability, comparisons of wildtype and mutant prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f3286ef48e851b615e6056e4fb874ce1
https://doi.org/10.1002/pro.3474
https://doi.org/10.1002/pro.3474
Autor:
Steven Molinski, Andrew J. Miles, Donghe Yang, Christine E. Bear, Stephanie Chin, Paul D. W. Eckford, Bonnie A. Wallace
Publikováno v:
The Journal of Biological Chemistry
Cystic fibrosis transmembrane conductance regulator (CFTR) is a multidomain membrane protein that functions as a phosphorylation-regulated anion channel. The interface between its two cytosolic nucleotide binding domains and coupling helices conferre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cd989f909032e2c0ba7c3ac4f865dd2
https://doi.org/10.1074/jbc.m116.762633
https://doi.org/10.1074/jbc.m116.762633
Autor:
Andrew J. Miles, Bonnie A. Wallace
Publikováno v:
Chemical Society Reviews. 45:4859-4872
Circular dichroism (CD) spectroscopy is a well-established technique for studying the secondary structures, dynamics, folding pathways, and interactions of soluble proteins, and is complementary to the high resolution but generally static structures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c514199d83dc8003fe3b0ddb51ae845
https://doi.org/10.1039/c5cs00084j
https://doi.org/10.1039/c5cs00084j
Autor:
James Tolchard, Samuel J. Walpole, Andrew J. Miles, Robin Maytum, Lawrence A. Eaglen, Ted Hackstadt, B. A. Wallace, Tharin M. A. Blumenschein
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Tarp (translocated actin recruiting phosphoprotein) is an effector protein common to all chlamydial species that functions to remodel the host-actin cytoskeleton during the initial stage of infection. In C. trachomatis, direct binding to actin monome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::4c94687c2f4a510055737126c2593605
https://ueaeprints.uea.ac.uk/id/eprint/65987/
https://ueaeprints.uea.ac.uk/id/eprint/65987/
Autor:
Andrew E. Dadson, Andrew J. Miles, Chuan-Hsi Hung, Clayton Sulak, Janusz Zukowski, Matthew R. Linford, David S. Jensen
Publikováno v:
Journal of Separation Science. 38:2968-2974
Three mixed-mode high-performance liquid chromatography columns packed with superficially porous carbon/nanodiamond/amine-polymer particles were used to separate mixtures of cannabinoids. Columns evaluated included: (i) reversed phase (C18 ), weak an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d808a0441242c5904fbc2d5e409b60e4
https://doi.org/10.1002/jssc.201500156
https://doi.org/10.1002/jssc.201500156
Autor:
Mohammed Ibrahim, Michael G. Landowski, Stacey J. Smith, Bhupinder Singh, Andrew J. Miles, David S. Jensen, Matthew R. Linford, Andrew E. Dadson, Chuan-Hsi Hung, Michael A. Vail
Publikováno v:
Surface and Interface Analysis. 47:815-823
We report a multi-instrument characterization of the carbon particles in carbon/polymer/nanodiamond core-shell materials used for high-performance liquid chromatography. These particles are prepared by the carbonization/pyrolysis of poly(divinylbenze
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d91ee7ca824f65699d979acb4ce34ffa
https://doi.org/10.1002/sia.5778
https://doi.org/10.1002/sia.5778
Autor:
James, Tolchard, Samuel J, Walpole, Andrew J, Miles, Robin, Maytum, Lawrence A, Eaglen, Ted, Hackstadt, B A, Wallace, Tharin M A, Blumenschein
Publikováno v:
Scientific Reports
Tarp (translocated actin recruiting phosphoprotein) is an effector protein common to all chlamydial species that functions to remodel the host-actin cytoskeleton during the initial stage of infection. In C. trachomatis, direct binding to actin monome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::538febc9047adabb2d097c5ae25a6e9e
https://pubmed.ncbi.nlm.nih.gov/29386631
https://pubmed.ncbi.nlm.nih.gov/29386631