Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Andrew J, Lindsay"'
Publikováno v:
Exploration of Targeted Anti-tumor Therapy, Vol 5, Iss 4, Pp 902-920 (2024)
Outcomes for women with breast cancer have improved dramatically in recent decades. However, many patients present with intrinsic drug resistance and others are initially sensitive to anti-cancer drugs but acquire resistance during the course of thei
Externí odkaz:
https://doaj.org/article/1abaed6f3abb40a2b7eb3d62dca53220
Autor:
Luke J. Joyce, Andrew J. Lindsay
Publikováno v:
Biochemistry and Biophysics Reports, Vol 38, Iss , Pp 101700- (2024)
Glioblastoma (GBM) is the most common and aggressive brain cancer in adults. The standard treatment is brutal and has changed little in 20 years, and more than 85% of patients will die within two years of their diagnosis. There is thus an urgent need
Externí odkaz:
https://doaj.org/article/5a3b2bb5546143278590df156f627e39
Autor:
Monique C. P. Mendonça, Yao Sun, Michael F. Cronin, Andrew J. Lindsay, John F. Cryan, Caitriona M. O’Driscoll
Publikováno v:
Pharmaceutics, Vol 15, Iss 2, p 520 (2023)
Huntington’s disease (HD) is a progressive inherited neurodegenerative disease caused by a CAG repeat expansion in the huntingtin gene, which is translated into the pathologic mutant huntingtin (mHTT) protein. Despite the great potential of HTT low
Externí odkaz:
https://doaj.org/article/33618e036dd34f8ebede77e2c30a28d4
Autor:
James V. Harte, Samantha L. Wakerlin, Andrew J. Lindsay, Justin V. McCarthy, Caroline Coleman-Vaughan
Publikováno v:
Viruses, Vol 14, Iss 10, p 2094 (2022)
SARS-CoV-2 cell–cell fusion and syncytiation is an emerging pathomechanism in COVID-19, but the precise factors contributing to the process remain ill-defined. In this study, we show that metalloproteases promote SARS-CoV-2 spike protein-induced sy
Externí odkaz:
https://doaj.org/article/c916257dcbd84600a0fbc372d7e706fe
Autor:
Andrew J. Lindsay, Ezra C. Wood
Publikováno v:
Atmospheric Measurement Techniques. 15:5455-5464
Nitrous acid (HONO) plays an important role in tropospheric oxidation chemistry as it is a precursor to the hydroxyl radical (OH). Measurements of HONO have been difficult historically due to instrument interferences and difficulties in sampling and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cb0b1a3e046729b74108ab285f8fa37
https://doi.org/10.5194/amt-15-5455-2022
https://doi.org/10.5194/amt-15-5455-2022
Autor:
Andrew J. Lindsay, Daniel C. Anderson, Rebecca A. Wernis, Yutong Liang, Allen H. Goldstein, Scott C. Herndon, Joseph R. Roscioli, Christoph Dyroff, Ed C. Fortner, Philip L. Croteau, Francesca Majluf, Jordan E. Krechmer, Tara I. Yacovitch, Walter B. Knighton, Ezra C. Wood
Publikováno v:
Atmospheric Chemistry and Physics. 22:4909-4928
Ozone (O3), a potent greenhouse gas that is detrimental to human health, is typically found in elevated concentrations within biomass burning (BB) smoke plumes. The radical species OH, HO2, and RO2 (known collectively as ROx) have central roles in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::617fb2c2df1550c96305a291e5168831
https://doi.org/10.5194/acp-22-4909-2022
https://doi.org/10.5194/acp-22-4909-2022
Autor:
John Fehilly, Olivia Carey, Eoghan Thomas O’Leary, Stephen O’Shea, Klaudia Juda, Rahel Fitzel, Pooja Selvaraj, Andrew J. Lindsay, Bálint Mészáros, Kellie Dean
SMAUG1 is a human RNA-binding protein that is known to be dysregulated in a wide range of diseases. It is evolutionarily conserved and has been shown to form condensates containing translationally repressed RNAs. This indicates that condensation is c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f67838b227ac88dd916f208640f1442
https://doi.org/10.1101/2023.02.09.527857
https://doi.org/10.1101/2023.02.09.527857
Autor:
Dieter Waschbüsch, Nicole Hübel, Edith Ossendorf, Evy Lobbestael, Veerle Baekelandt, Andrew J Lindsay, Mary W McCaffrey, Amir R Khan, Angelika Barnekow
Publikováno v:
PLoS ONE, Vol 14, Iss 1, p e0208889 (2019)
The Rab family of small GTPases regulate various aspects of cellular dynamics in eukaryotic cells. Membrane trafficking has emerged as central to the functions of leucine-rich repeat kinase 2 (LRRK2), which is associated with inherited and sporadic f
Externí odkaz:
https://doaj.org/article/196f08b326604839b85aa77db909dee8
Publikováno v:
Encyclopedia of Cell Biology ISBN: 9780128216248
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee23a4c75b7c3bf3d10f3ff27b829269
https://doi.org/10.1016/b978-0-12-821618-7.00053-5
https://doi.org/10.1016/b978-0-12-821618-7.00053-5
Autor:
Elizabeth S Taglauer, Patrycja A Artemiuk, Sara R Hanscom, Andrew J Lindsay, Danielle Wuebbolt, Fionnuala M Breathnach, Elizabeth C Tully, Amir R Khan, Mary W McCaffrey
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0184864 (2017)
Rab proteins are a family of small GTPases involved in a variety of cellular processes. The Rab11 subfamily in particular directs key steps of intracellular functions involving vesicle trafficking of the endosomal recycling pathway. This Rab subfamil
Externí odkaz:
https://doaj.org/article/409fc489ea6c46019953037437eb2fdd