Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Andrew J, Konecny"'
Autor:
Kyle G. Williams, Ramya Kongala, Donna M. Shows, Andrew J. Konecny, Duncan C. Hindmarch, Astrid S. Clarke, James D. Lord
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 17, Iss 1, Pp 119-130 (2024)
Background & Aims: Inflammatory bowel disease (IBD) causes a marked increase in the number of T cells in the intestinal mucosa. Debate exists about whether these excess cells arise from local clonal proliferation or recruitment from the periphery. Me
Externí odkaz:
https://doaj.org/article/ee9454018c844a7b80fe3559c671e348
Publikováno v:
PLoS ONE, Vol 18, Iss 11, p e0285918 (2023)
ObjectivesMucosal-Associated Invariant T (MAIT) cells are T cells with a semi-invariant T cell receptor (TCR), recognizing riboflavin precursors presented by a non-polymorphic MR1 molecule. As these precursors are produced by the gut microbiome, we c
Externí odkaz:
https://doaj.org/article/a8d7982345744f61a52d4f080210c251
Autor:
Amiko M. Uchida, Elisa K. Boden, Eddie A. James, Donna M. Shows, Andrew J. Konecny, James D. Lord
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 10, Iss 3, Pp 507-526 (2020)
Background & Aims: Crohn’s disease (CD) likely represents decreased immune tolerance to intestinal bacterial antigens. Most CD patients have high titers of antibodies to intestinal commensal proteins, including the outer membrane porin C (OmpC) of
Externí odkaz:
https://doaj.org/article/98759850dda64024b22ff773edf37060
Publikováno v:
ImmunoHorizons. 6(3)
Successful treatment of inflammatory bowel disease (IBD) with the anti-integrin α
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a8fee797b3f558cfc73d8ba62b9d4627
https://pubmed.ncbi.nlm.nih.gov/35273097
https://pubmed.ncbi.nlm.nih.gov/35273097
Autor:
Raphael Gottardo, Florian Mair, Martin Prlic, Nicholas Franko, Sarah C. Vick, Joshua T. Schiffer, Evan Greene, Helen Y. Chu, Caitlin R Wolf, Jennifer Logue, Jim Boonyaratanakornkit, Jennifer M. Lund, Marie Frutoso, Andrew J. Konecny
Publikováno v:
medRxiv
article-version (status) pre
article-version (number) 1
article-version (status) pre
article-version (number) 1
SARS-CoV-2 infection has caused a lasting global pandemic costing millions of lives and untold additional costs. Understanding the immune response to SARS-CoV-2 has been one of the main challenges in the past year in order to decipher mechanisms of h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9735c85dcfa272362097b8c1c5ef0d5
https://pubmed.ncbi.nlm.nih.gov/33791720
https://pubmed.ncbi.nlm.nih.gov/33791720
Autor:
Martin Prlic, Brittany Barber, Andrew J. Konecny, Florian Mair, Jami R. Erickson, Evan Greene, Douglas R. Dixon, Marie Frutoso, Raphael Gottardo, Valentin Voillet
Immunotherapies to treat cancer have achieved remarkable successes, but major challenges persist. An inherent weakness of current treatment approaches is that therapeutically targeted pathways are not only found in tumors, but also in tissue microenv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2964b42029b93b9063bf2b82f00f8275
https://doi.org/10.21203/rs.3.rs-356214/v1
https://doi.org/10.21203/rs.3.rs-356214/v1
Autor:
Florian Mair, Jami R. Erickson, Marie Frutoso, Andrew J. Konecny, Evan Greene, Valentin Voillet, Nicholas J. Maurice, Anthony Rongvaux, Douglas Dixon, Brittany Barber, Raphael Gottardo, Martin Prlic
Publikováno v:
Nature. 605(7911)
Immunotherapies have achieved remarkable successes in the treatment of cancer, but major challenges remain1,2. An inherent weakness of current treatment approaches is that therapeutically targeted pathways are not restricted to tumours, but are also
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::532cb8aaeaf903b03968fe944f81ae2b
https://pubmed.ncbi.nlm.nih.gov/35726061
https://pubmed.ncbi.nlm.nih.gov/35726061