Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Andrew J, Childs"'
Publikováno v:
Stem Cell Research, Vol 21, Iss C, Pp 193-201 (2017)
Primordial germ cells undergo three significant processes on their path to becoming primary oocytes: the initiation of meiosis, the formation and breakdown of germ cell nests, and the assembly of single oocytes into primordial follicles. However at t
Externí odkaz:
https://doaj.org/article/5d76f1b6b2d540ba800b678a61a46c43
Autor:
Samantha M Mirczuk, Andrew J Lessey, Alice R Catterick, Rebecca M Perrett, Christopher J Scudder, Jordan E Read, Victoria J Lipscomb, Stijn J Niessen, Andrew J Childs, Craig A McArdle, Imelda M McGonnell, Robert C Fowkes
Publikováno v:
Cells, Vol 8, Iss 9, p 1086 (2019)
C-type natriuretic peptide (CNP) is the most conserved member of the mammalian natriuretic peptide family, and is implicated in the endocrine regulation of growth, metabolism and reproduction. CNP is expressed throughout the body, but is particularly
Externí odkaz:
https://doaj.org/article/f54fc781a0414f39b5e1f910f41b64d7
Autor:
Roseanne Rosario, Panagiotis Filis, Victoria Tessyman, Hazel Kinnell, Andrew J Childs, Nicola K Gray, Richard A Anderson
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0163987 (2016)
Germ cell development and primordial follicle formation during fetal life is critical in establishing the pool of oocytes that subsequently determines the reproductive lifespan of women. Fragile X-associated primary ovarian insufficiency (FXPOI) is c
Externí odkaz:
https://doaj.org/article/62093ef142ac410bbd57b8d4a8d62b1c
Autor:
Rosemary A L Bayne, Hazel L Kinnell, Shiona M Coutts, Jing He, Andrew J Childs, Richard A Anderson
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0119819 (2015)
During human fetal ovary development, the process of primordial follicle formation is immediately preceded by a highly dynamic period of germ cell and somatic cell reorganisation. This is regulated by germ-cell specific transcription regulators, by t
Externí odkaz:
https://doaj.org/article/e3702f6da7854075b838c227c967632c
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0136009 (2015)
Externí odkaz:
https://doaj.org/article/94589f548d2841089cf398507312c3bf
Publikováno v:
PLoS ONE, Vol 8, Iss 11 (2013)
[This corrects the article DOI: 10.1371/journal.pone.0073996.].
Externí odkaz:
https://doaj.org/article/3e5210d4022343c49fce31e322680c96
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e73996 (2013)
The Deleted in Azoospermia gene family encodes three germ cell-specific RNA-binding proteins (DAZ, DAZL and BOLL) that are essential for gametogenesis in diverse species. Targeted disruption of Boll in mice causes male-specific spermiogenic defects,
Externí odkaz:
https://doaj.org/article/2ab763f3c2da4778870031a66061fb79
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e20249 (2011)
The development of mammalian fetal germ cells along oogenic or spermatogenic fate trajectories is dictated by signals from the surrounding gonadal environment. Germ cells in the fetal testis enter mitotic arrest, whilst those in the fetal ovary under
Externí odkaz:
https://doaj.org/article/3b56bb9bc6814afdb77ef5478b07358c
Autor:
Rupert Ollinger, Andrew J Childs, Hannah M Burgess, Robert M Speed, Pia R Lundegaard, Nicola Reynolds, Nicola K Gray, Howard J Cooke, Ian R Adams
Publikováno v:
PLoS Genetics, Vol 4, Iss 9, p e1000199 (2008)
As genetic information is transmitted through successive generations, it passes between pluripotent cells in the early embryo and germ cells in the developing foetus and adult animal. Tex19.1 encodes a protein of unknown function, whose expression is
Externí odkaz:
https://doaj.org/article/d9aacbdcd60f44848bc41f080a15718b
Autor:
Hazel L Stewart, Roseanne Rosario, Richard A. Anderson, Ian R. Adams, James H. Crichton, Andrew J. Childs
Publikováno v:
Rosario, R, Crichton, J H, Stewart, H L, Childs, A J, Adams, I R & Anderson, R A 2019, ' Dazl determines primordial follicle formation through the translational regulation of Tex14 ', The FASEB Journal, vol. 33, no. 12, pp. 14221-14233 . https://doi.org/10.1096/fj.201901247R
Deleted in azoospermia-like (DAZL) is a germ cell RNA-binding protein that is essential for entry and progression through meiosis. The phenotype of the Dazl knockout mouse has extensive germ cell loss because of incomplete meiosis. We have created a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a4afe419b02bfbd0646836450b0f908
https://hdl.handle.net/20.500.11820/f55182c9-81ef-44fa-b4de-c66c52629ba2
https://hdl.handle.net/20.500.11820/f55182c9-81ef-44fa-b4de-c66c52629ba2
