Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Andrew J, Bett"'
Autor:
Xiao Xiao, Arthur Fridman, Lu Zhang, Pavlo Pristatsky, Eberhard Durr, Michael Minnier, Aimin Tang, Kara S. Cox, Zhiyun Wen, Renee Moore, Dongrui Tian, Jennifer D. Galli, Scott Cosmi, Michael J. Eddins, Nicole L. Sullivan, Xiaodong Yan, Andrew J. Bett, Hua-Poo Su, Kalpit A. Vora, Zhifeng Chen, Lan Zhang
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Here, Xiao et al. isolate a large panel of antibodies against human metapneumovirus fusion protein from human B cells, and characterize their epitopes, neutralization activities, and antigen binding specificity, providing a useful framework for under
Externí odkaz:
https://doaj.org/article/39a413c0e00f4ee69f63888b87fa5809
Autor:
Lauren A. Austin, Jeffrey S. Smith, Debbie D. Nahas, Andrew Danzinger, Susan Secore, Gregory O’Donnell, Scott Radcliffe, Shuai Hu, Jeffrey Perley, Andrew J. Bett, Marian E. Gindy
Publikováno v:
Molecular Pharmaceutics. 20:279-289
mRNA vaccines have recently received significant attention due to their role in combating the SARS-CoV-2 pandemic. As a platform, mRNA vaccines have been shown to elicit strong humoral and cellular immune responses with acceptable safety profiles for
Autor:
Brian K. Meyer, Mark A.F. Kendall, Donna M. Williams, Andrew J. Bett, Sheri Dubey, Renee C. Gentzel, Danilo Casimiro, Angus Forster, Holly Corbett, Michael Crichton, S. Ben Baker, Robert K. Evans, Akhilesh Bhambhani
Publikováno v:
Vaccine: X, Vol 2, Iss , Pp - (2019)
The human papillomavirus (HPV) 9-valent, recombinant vaccine (Gardasil™9) helps protect young adults (males and females) against anogenital cancers and genital warts caused by certain HPV genotypes (ref. Gardasil™9 insert). This vaccine is admini
Externí odkaz:
https://doaj.org/article/23362dc9fcfe434d85a9942b7889ce62
Potent neutralizing antibodies elicited by dengue vaccine in rhesus macaque target diverse epitopes.
Autor:
Leike Li, Weixu Meng, Melanie Horton, Daniel R DiStefano, Elizabeth A Thoryk, Jennifer M Pfaff, Qihui Wang, Georgina T Salazar, Trevor Barnes, Benjamin J Doranz, Andrew J Bett, Danilo R Casimiro, Kalpit A Vora, Zhiqiang An, Ningyan Zhang
Publikováno v:
PLoS Pathogens, Vol 15, Iss 6, p e1007716 (2019)
There is still no safe and effective vaccine against dengue virus infection. Epidemics of dengue virus infection are increasingly a threat to human health around the world. Antibodies generated in response to dengue infection have been shown to impac
Externí odkaz:
https://doaj.org/article/987313e68b584a3482591ce5d30cb479
Autor:
Wei Zhang, I-Ming Wang, Changxi Wang, Liya Lin, Xianghua Chai, Jinghua Wu, Andrew J. Bett, Dhanasekaran Govindarajan, Danilo R. Casimiro, Xiao Liu
Publikováno v:
Frontiers in Immunology, Vol 7 (2016)
Large-scale study of the properties of T-cell receptor (TCR) and B-cell receptor (BCR) repertoires through next-generation sequencing is providing excellent insights into the understanding of adaptive immune responses. Variable(Diversity)Joining V(D)
Externí odkaz:
https://doaj.org/article/cc01d3d261ed4259bf5ccf3da2407da0
Autor:
Dhanasekaran Govindarajan, Liming Guan, Steven Meschino, Arthur Fridman, Ansu Bagchi, Irene Pak, Jan ter Meulen, Danilo R Casimiro, Andrew J Bett
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0152209 (2016)
Dengue is one of the most important mosquito-borne infections accounting for severe morbidity and mortality worldwide. Recently, the tetravalent chimeric live attenuated Dengue vaccine Dengvaxia® was approved for use in several dengue endemic countr
Externí odkaz:
https://doaj.org/article/d9159dd00b534679b40888da1c3e0a7b
Autor:
Jessica A Flynn, Eberhard Durr, Ryan Swoyer, Pedro J Cejas, Melanie S Horton, Jennifer D Galli, Scott A Cosmi, Amy S Espeseth, Andrew J Bett, Lan Zhang
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0164789 (2016)
Infection with Respiratory Syncytial Virus (RSV) causes both upper and lower respiratory tract disease in humans, leading to significant morbidity and mortality in both young children and older adults. Currently, there is no licensed vaccine availabl
Externí odkaz:
https://doaj.org/article/48f35b7eeaad4ea8b2956b94461371da
Autor:
Amy S. Espeseth, Maoli Yuan, Michael Citron, Lucia Reiserova, Gavin Morrow, Aaron Wilson, Melanie Horton, Mark Rukhman, Keith Kinek, Fuxiang Hou, Shui L. Li, Fengsheng Li, Yesle Choi, Gwen Heidecker, Bin Luo, Guoxin Wu, Lan Zhang, Erica Strable, Joanne DeStefano, Susan Secore, Tarit K. Mukhopadhyay, Douglas D. Richardson, Eddy Sayeed, Lisa S. Welch, Andrew J. Bett, Mark B. Feinberg, Swati B. Gupta, Christopher L. Cooper, Christopher L. Parks
Publikováno v:
EBioMedicine. 82
To investigate a vaccine technology with potential to protect against coronavirus disease 2019 (COVID-19) and reduce transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with a single vaccine dose, we developed a SARS-CoV-2 ca
Autor:
Xiao Xiao, Arthur Fridman, Lu Zhang, Pavlo Pristatsky, Eberhard Durr, Michael Minnier, Aimin Tang, Kara S. Cox, Zhiyun Wen, Renee Moore, Dongrui Tian, Jennifer D. Galli, Scott Cosmi, Michael J. Eddins, Nicole L. Sullivan, Xiaodong Yan, Andrew J. Bett, Hua-Poo Su, Kalpit A. Vora, Zhifeng Chen, Lan Zhang
Publikováno v:
Nature communications. 13(1)
Human metapneumovirus (hMPV) belongs to thePneumoviridaefamily and is closely related to respiratory syncytial virus (RSV). The surface fusion (F) glycoprotein mediates viral fusion and is the primary target of neutralizing antibodies against hMPV. H
Autor:
Zhiyun Wen, Zhifeng Chen, Nicole L Sullivan, Kara S. Cox, Xiao Xiao, Deeptak Verma, Aimin Tang, Kerim Babaoglu, Andrew J. Bett, Lan Zhang, Jennifer D. Galli, Michael Minnier, Kalpit A. Vora, Cheryl Callahan, Deborah D. Nahas, Scott Cosmi, Hua Su
Publikováno v:
mAbs
Respiratory syncytial virus (RSV) is a leading cause of lower respiratory tract infection in young children and older adults. Currently, no licensed vaccine is available, and therapeutic options are limited. The primary target of neutralizing antibod