Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Andrew I. Jobling"'
Autor:
Josephine H. C. Wong, Jessica Y. W. Ma, Andrew I. Jobling, Alice Brandli, Ursula Greferath, Erica L. Fletcher, Kirstan A. Vessey
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Age-related macular degeneration (AMD) is a leading cause of irreversible vision loss in the older population. Classical hallmarks of early and intermediate AMD are accumulation of drusen, a waste deposit formed under the retina, and pigmentary abnor
Externí odkaz:
https://doaj.org/article/7a461a36e84249eebe75654648f35fae
Autor:
Sara Nencini, Michael Morgan, Jenny Thai, Andrew I. Jobling, Stuart B. Mazzone, Jason J. Ivanusic
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Piezo2 is a mechanically gated ion-channel that has a well-defined role in innocuous mechanical sensitivity, but recently has also been suggested to play a role in mechanically induced pain. Here we have explored a role for Piezo2 in mechanically evo
Externí odkaz:
https://doaj.org/article/8b33c2abbe6a4312bb79fef7be7bb105
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
Microglia, the resident immune cells of the central nervous system (CNS), were once considered quiescent cells that sat in readiness for reacting to disease and injury. Over the last decade, however, it has become clear that microglia play essential
Externí odkaz:
https://doaj.org/article/27dc90e2fdd44d4794e7b062efd1d495
Autor:
Kiana Kakavand, Andrew I. Jobling, Ursula Greferath, Kirstan A. Vessey, Robb U. de Iongh, Erica L. Fletcher
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
Photoreceptor death contributes to 50% of irreversible vision loss in the western world. Pro23His (P23H) transgenic albino rat strains are widely used models for the most common rhodopsin gene mutation associated with the autosomal dominant form of r
Externí odkaz:
https://doaj.org/article/6f4169eef20540858345535f0fb8a25b
Autor:
Abrez Hussain Batcha, Una Greferath, Andrew I. Jobling, Kirstan A. Vessey, Michelle M. Ward, Jess Nithianantharajah, Anthony J. Hannan, Michael Kalloniatis, Erica L. Fletcher
Publikováno v:
Neurobiology of Disease, Vol 45, Iss 3, Pp 887-896 (2012)
Huntington's disease (HD) is a progressive neurological disease characterised by motor dysfunction, cognitive impairment and personality changes. Previous work in HD patients and animal models of the disease has also highlighted retinal involvement.
Externí odkaz:
https://doaj.org/article/996c6baf695547819f0e40f1137328df
Autor:
Jessica Y.W. Ma, Ursula Greferath, Josephine H.C. Wong, Linda J. Fothergill, Andrew I. Jobling, Kirstan A. Vessey, Erica L. Fletcher
Publikováno v:
Neurobiology of Aging. 128:1-16
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9065b6d9847b4bcc51ccf4f163ddcf34
https://doi.org/10.1016/j.neurobiolaging.2023.03.003
https://doi.org/10.1016/j.neurobiolaging.2023.03.003
Autor:
Kirstan A Vessey, Andrew I Jobling, Mai X. Tran, Anna Y. Wang, Ursula Greferath, Erica L. Fletcher
Publikováno v:
Autophagy. 18:2368-2384
Age-related macular degeneration (AMD) is a leading cause of vision loss with recent evidence indicating an important role for macroautophagy/autophagy in disease progression. In this study we investigate the efficacy of targeting autophagy for slowi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d14e2d6e3a5aa76cb00c0dea00344719
https://doi.org/10.1080/15548627.2022.2034131
https://doi.org/10.1080/15548627.2022.2034131
Publikováno v:
Clinicalexperimental ophthalmologyREFERENCES.
Diabetic retinopathy is the most feared complication for those with diabetes. Although visible vascular pathology traditionally defines the management of this condition, it is now recognised that a range of cellular changes occur in the retina from a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bbaf52e7c57356c8e4119058d98e926
https://pubmed.ncbi.nlm.nih.gov/36349522
https://pubmed.ncbi.nlm.nih.gov/36349522
Autor:
Kirstan A. Vessey, Anna Ym Wang, Bang V. Bui, Quan Findlay, Andrew I Jobling, Alice Brandli, Michael A Dixon, Ursula Greferath, Erica L. Fletcher, Pei Ying Lee
Publikováno v:
Clinical and Experimental Optometry. 103:562-571
Glaucoma is a neurodegenerative disease characterised by progressive damage to the retinal ganglion cells (RGCs), the output neurons of the retina. RGCs are a heterogenous class of retinal neurons which can be classified into multiple types based on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10be247b7977f80f9dc388a7dce97010
https://doi.org/10.1111/cxo.13031
https://doi.org/10.1111/cxo.13031
Autor:
Elena Ivanova, Connie H Wong, Bang V. Bui, Gene Venables, Samuel A Mills, Michael A Dixon, Flora Hui, Zheng He, Kirstan A. Vessey, Vickie Hy Wong, Josh Tonc, James C Young, Botir T. Sagdullaev, Andrew I Jobling, Ursula Greferath, Erica L. Fletcher, Joanna A. Phipps
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance This work identifies a role for microglia, the innate immune cells of the CNS, in the local control of the retinal vasculature and identifies deficits early in diabetes. Microglia contact neurons and vasculature and express several vasoa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c184d211cc76f8f4bfa1337044ce4ff2
https://doi.org/10.1073/pnas.2112561118
https://doi.org/10.1073/pnas.2112561118