Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Andrew Huehn"'
Publikováno v:
Proc Natl Acad Sci U S A
Microtubules are tubular polymers with essential roles in numerous cellular activities. Structures of microtubules have been captured at increasing resolution by cryo-EM. However, dynamic properties of the microtubule are key to its function, and thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79704188202228bd594ac5c7892f0e04
https://doi.org/10.1073/pnas.2001546117
https://doi.org/10.1073/pnas.2001546117
Autor:
Wenxiang Cao, Ewa Prochniewicz, David D. Thomas, Charles V. Sindelar, Teresa T. Bonello, Hyeran Kang, Gregory A. Voth, Enrique M. De La Cruz, Peter W. Gunning, Andrew Huehn, Anthony C. Schramm, Glen M. Hocky, Karina Negrón, Jean Garcia, W. Austin Elam
Publikováno v:
Journal of Biological Chemistry. 292:19565-19579
Many biological processes, including cell division, growth, and motility, rely on rapid remodeling of the actin cytoskeleton and on actin filament severing by the regulatory protein cofilin. Phosphorylation of vertebrate cofilin at Ser-3 regulates bo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f684af6a378f6b2df8c90e2fa5d00e0
https://doi.org/10.1074/jbc.m117.808378
https://doi.org/10.1074/jbc.m117.808378
Autor:
Charles V. Sindelar, Andrew Huehn
Publikováno v:
Journal of Molecular Biology. 428:1-4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::192037db3e7f04092fb97cacd272dbd2
https://doi.org/10.1016/j.jmb.2015.11.005
https://doi.org/10.1016/j.jmb.2015.11.005
Autor:
Nadya I. Tarasova, Bahara Saleh, Andrew Huehn, Stephen K. Anderson, Michael Dean, Hong Lou, Hongchuan Li
Publikováno v:
Cancers
Cancers, Vol 12, Iss 2219, p 2219 (2020)
Volume 12
Issue 8
Cancers, Vol 12, Iss 2219, p 2219 (2020)
Volume 12
Issue 8
(1) Background: The hedgehog (HH) signaling pathway is a key regulator of embryonic patterning, tissue regeneration, stem cell renewal, and cancer growth. The smoothened (SMO) protein regulates the HH signaling pathway and has demonstrated oncogenic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfd7061366e86c33e1f70582e83a5908
https://doi.org/10.3390/cancers12082219
https://doi.org/10.3390/cancers12082219
Autor:
Ahmet Mentes, Andrew Huehn, Xueqi Liu, Adam Zwolak, Roberto Dominguez, Henry Shuman, E. Michael Ostap, Charles V. Sindelar
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 115(6)
Myosins adjust their power outputs in response to mechanical loads in an isoform-dependent manner, resulting in their ability to dynamically adapt to a range of motile challenges. Here, we reveal the structural basis for force-sensing based on near-a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::881b82b924ae9eae86267cbf38cb6ccb
https://pubmed.ncbi.nlm.nih.gov/29358376
https://pubmed.ncbi.nlm.nih.gov/29358376
Autor:
Charles V. Sindelar, Xueqi Liu, Wenxiang Cao, W. Austin Elam, Enrique M. De La Cruz, Andrew Huehn
Publikováno v:
The Journal of biological chemistry. 293(15)
Cofilin/ADF proteins are actin-remodeling proteins, essential for actin disassembly in various cellular processes, including cell division, intracellular transport, and motility. Cofilins bind actin filaments cooperatively and sever them preferential
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdb2e16c0b0781626e6086e42e8846a6
https://pubmed.ncbi.nlm.nih.gov/29463680
https://pubmed.ncbi.nlm.nih.gov/29463680
Autor:
Geraldine M. O’Connor, Hongchuan Li, Andrew Huehn, Sarah Cooley, Jeffrey S. Miller, Stephen K. Anderson, Paul W. Wright
Publikováno v:
Genes and immunity
Members of the human KIR (killer cell immunoglobulin-like receptor) class I major histocompatibility complex receptor gene family contain multiple promoters that determine the variegated expression of KIR on natural killer cells. In order to identify
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b01584f93056e041d6024cc501d6e221
https://doi.org/10.1038/gene.2014.34
https://doi.org/10.1038/gene.2014.34
Autor:
Adam Zwolak, Andrew Huehn, Ahmet Mentes, Charles V. Sindelar, Xueqi Liu, Henry Shuman, Roberto Dominguez, E. Michael Ostap
Publikováno v:
Biophysical Journal. 114:319a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::64bb4ca26b83b1b09c0beb640f6135df
https://doi.org/10.1016/j.bpj.2017.11.1796
https://doi.org/10.1016/j.bpj.2017.11.1796
Publikováno v:
Biophysical Journal. 114:145a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a943b9d02696aaa27720e2740c2e119c
https://doi.org/10.1016/j.bpj.2017.11.812
https://doi.org/10.1016/j.bpj.2017.11.812
Publikováno v:
The Journal of Immunology. 190:63.31-63.31
The variegated expression of the human KIR family of class I MHC receptors provides an interesting model system for the study of stochastic activation of gene transcription. Previous studies have linked distal KIR promoter transcription to the initia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5fc419e08902a88c5831c584ff193a12
https://doi.org/10.4049/jimmunol.190.supp.63.31
https://doi.org/10.4049/jimmunol.190.supp.63.31