Comparing open and minimally invasive surgical procedures for oesophagectomy in the treatment of cancer: the ROMIO (Randomised Oesophagectomy: Minimally Invasive or Open) feasibility study and pilot trial

Autor: Chris Metcalfe, Kerry Avery, Richard Berrisford, Paul Barham, Sian M Noble, Aida Moure Fernandez, George Hanna, Robert Goldin, Jackie Elliott, Timothy Wheatley, Grant Sanders, Andrew Hollowood, Stephen Falk, Dan Titcomb, Christopher Streets, Jenny L Donovan, Jane M Blazeby

Publikováno v: Health Technology Assessment, Vol 20, Iss 48 (2016)

Background: Localised oesophageal cancer can be curatively treated with surgery (oesophagectomy) but the procedure is complex with a risk of complications, negative effects on quality of life and a recovery period of 6–9 months. Minimal-access surg

Externí odkaz: https://doaj.org/article/f84555b9772e4d3bb691f8c2351ea501

Laparoscopically assisted versus open oesophagectomy for patients with oesophageal cancer-the Randomised Oesophagectomy: Minimally Invasive or Open (ROMIO) study: protocol for a randomised controlled trial (RCT)

Autor: Martyn Lee Humphreys, Christopher Streets, Chris A Rogers, Naheed Farooq, Anni Skilton, Kerry N L Avery, Timothy J. Underwood, James P. Byrne, Newton Wong, Carolyn Hindmarsh, Grant Sanders, Rachel Cm Brierley, Richard J E Skipworth, Natalie S Blencowe, Robin A Wickens, Kish Pursnani, Bilal Alkhaffaf, Joanna Nicklin, R Berrisford, Nicola Rea, Simon L. Parsons, Jill Cooke, Alexander P. Boddy, Richard Krysztopik, Chris Metcalfe, David J. Bowrey, William Hollingworth, Fergus Noble, Arun Ariyarathenam, Marcus Jepson, Rachel Schranz, Ram Chaparala, Rebecca J Houlihan, David Exon, Paul Wilkerson, Tim Wheatley, Jamie Kelly, Graeme Couper, Lucy Culliford, Sally Maitland, Rachael Heys, Caoimhe Rice, Chris Deans, Sukhbir Ubhi, Lucy Howie, R S Vohra, James A Catton, Jenny L Donovan, CP Barham, Jane M Blazeby, Peter Lamb, Katy A Chalmers, Alexandra Williams, Sian Cousins, Paul Turner, Neil T. Welch, Dan Titcomb, Aida Moure-Fernandez, Khurshid Akhtar, Vinutha Daya Shetty, Rachel Melhado, Andrew Hollowood, Robert N. Williams, Daisy Gaunt, Joanne Smith, Benjamin Howes, Jackie Elliott

Publikováno v: BMJ Open
Brierley, RC, Gaunt, D, Metcalfe, C, Blazeby, JM, Blencowe, NS, Jepson, M, Berrisford, RG, Avery, KNL, Hollingworth, W, Rice, CT, Moure-Fernandez, A, Wong, N & Barham, CP 2019, ' Laparoscopically assisted versus open oesophagectomy for patients with oesophageal cancer-the Randomised Oesophagectomy: Minimally Invasive or Open (ROMIO) study: protocol for a randomised controlled trial (RCT). ', BMJ Open . https://doi.org/10.1136/bmjopen-2019-030907
Brierley, R C M, Gaunt, D M, Metcalfe, C, Blazeby, J M, Blencowe, N S, Jepson, M, Berrisford, R, Avery, K N L, Hollingworth, W, Rice, C, Moure Fernandez, A, Wong, N A C S, Nicklin, J K, Skilton, A, Boddy, A P, Byrne, J, Underwood, T, Vohra, R S, Catton, J A, Pursnani, K, Melhado, R, Alkhaffaf, B, Krysztopik, R, Lamb, P, Culliford, L A, Rogers, C A, Howes, B, Chalmers, K A, Cousins, S E, Elliott, J, Donovan, J L, Heys, R L, Wickens, R A, Wilkeron, P, Hollowood, A, Streets, C G, Titcomb, D R, Humphreys, M L, Wheatley, T, Sanders, G, Ariyarathenam, A, Kelly, J, Noble, F, Couper, G, Skipworth, R J E, Deans, C, Ubhi, S, Williams, R, Bowrey, D, Exon, D, Turner, P, Shetty, V, Chaparala, R, Akhtar, K, Farooq, N, Parsons, S, Welch, N, Houlihan, R, Smith, J, Schranz, R, Rea, N, Cooke, J, Williams, A, Hindmarsh, C, Maitland, S, Howie, L & Barham, C P 2019, ' Laparoscopically assisted vs open oesophagectomy for patients with oesophageal cancer – the ROMIO (Randomised Oesophagectomy : Minimally Invasive or Open) study: protocol for a randomized controlled trial (RCT) ', BMJ Open, vol. 9, e030907 . https://doi.org/10.1136/bmjopen-2019-030907
Brierley, R, Gaunt, D M, Metcalfe, C, Blazeby, J M, Blencowe, N S, Jepson, M, Berrisford, R, Avery, K N L, Hollingworth, W, Rice, C T, Moure-Fernandez, A, Wong, N A, Nicklin, J, Skilton, A, Boddy, A, Byrne, J, Underwood, T, Vohra, R, Catton, J A, Pursnani, K, Melhado, R, Alkhaffaf, B, Krysztopik, R, Lamb, P, Culliford, L A, Rogers, C A, Howes, B, Chalmers, K, Cousins, S, Elliott, J, Donovan, J, Heys, R, Wickens, R A, Wilkerson, P, Hollowood, A, Streets, C, Titcomb, D, Humphreys, M L, Wheatley, T, Sanders, G, Ariyarathenam, A, Kelly, J, Noble, F, Couper, G W, Skipworth, R J E, Deans, C, Ubhi, S, Williams, R, Bowrey, D, Exon, D, Turner, P, Shetty, V, Chaparala, R, Akhtar, K, Farooq, N, Parsons, S L, Welch, N T, Houlihan, R J, Smith, J, Schranz, R, Rea, N, Cooke, J, Williams, A, Hindmarsh, C, Maitland, S, Howie, L & Barham, C P 2019, ' Laparoscopically assisted vs open oesophagectomy for patients with oesophageal cancer – the ROMIO (Randomised Oesophagectomy: Minimally Invasive or Open) study: protocol for a randomized controlled trial (RCT) ', BMJ Open . https://doi.org/10.1136/bmjopen-2019-030907

IntroductionSurgery (oesophagectomy), with neoadjuvant chemo(radio)therapy, is the main curative treatment for patients with oesophageal cancer. Several surgical approaches can be used to remove an oesophageal tumour. The Ivor Lewis (two-phase proced

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96fb67eff7ce30f29e410d8d266edd62
https://pubmed.ncbi.nlm.nih.gov/31748296

Comparing open and minimally invasive surgical procedures for oesophagectomy in the treatment of cancer: the ROMIO (Randomised Oesophagectomy: Minimally Invasive or Open) feasibility study and pilot trial

Autor: T Wheatley, Robert D. Goldin, Paul Barham, Jenny L Donovan, Andrew Hollowood, Christopher Streets, Aida Moure Fernandez, Chris Metcalfe, Kerry N L Avery, Richard G. Berrisford, Stephen Falk, Grant Sanders, Sian M Noble, Dan Titcomb, George B. Hanna, Jane M Blazeby, Jackie Elliott

Publikováno v: Health Technology Assessment, Vol 20, Iss 48 (2016)
Metcalfe, C, Avery, K, Noble, S, Moure Fernandez, A, Donovan, J & Blazeby, J 2016, ' Comparing open and minimally invasive surgical procedures for oesophagectomy in the treatment of cancer : the ROMIO (Randomised Oesophagectomy: Minimally Invasive or Open) feasibility study and pilot trial ', Health Technology Assessment, vol. 20, no. 48 . https://doi.org/10.3310/hta20480

BackgroundLocalised oesophageal cancer can be curatively treated with surgery (oesophagectomy) but the procedure is complex with a risk of complications, negative effects on quality of life and a recovery period of 6–9 months. Minimal-access surger

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c51777d08ca48525cac7b75eb6c6060a
https://doaj.org/article/f84555b9772e4d3bb691f8c2351ea501

Insulin-like growth factor binding protein-3: relationship to the development of gastric pre-malignancy and gastric adenocarcinoma (United Kingdom)

Autor: Derek Alderson, Roger Feakins, P.B. Savage, Jyoti Gupta, Jeffrey M P Holly, Moganaden Moorghen, Andrew Hollowood, P.V. Newcomb, Zun-Wu Zhang

Publikováno v: Cancer Causes & Control. 15:211-218

IGF family proteins play a pivotal role in regulating cell growth and apoptosis in normal and tumour tissues. IGFBP-3 is the major binding protein of IGFs and modulates the bioactivity of IGFs. To examine the role of IGFBP-3 in gastric cancer, an IGF

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9867c5672bfa96c930a363bfac5a6c7
https://doi.org/10.1023/b:caco.0000019510.96285.e9

Using real-time, anonymous staff feedback to improve staff experience and engagement

Autor: Anne Frampton, Fiona Fox, Ruta Margelyte, Sabi Redwood, Kate Northstone, Andrew Hollowood, Stephanie Smith-Clarke

Publikováno v: BMJ Quality Improvement Reports
Frampton, A, Fox, F, Hollowood, A, Northstone, K, Margelyte, R, Smith-Clarke, S & Redwood, S 2017, ' Using real-time, anonymous staff feedback to improve staff experience and engagement ', BMJ Quality Improvement Reports, vol. 6, u220946.w7041 . https://doi.org/10.1136/bmjquality.u220946.w7041
BASE-Bielefeld Academic Search Engine

Improving staff engagement has become a priority for NHS leaders, although efforts in this area vary between organisations. University Hospital Bristol NHS Foundation Trust (UH Bristol) is a tertiary teaching hospital where concerns about staff satis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec8fe92638ea2185bef16d6c68fc0d70
https://doi.org/10.1136/bmjquality.u220946.w7041