Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Andrew Hefner"'
Autor:
Mohamed K. Abdelhakiem, Riyue Bao, Phillip M. Pifer, David Molkentine, Jessica Molkentine, Andrew Hefner, Beth Beadle, John V. Heymach, Jason J. Luke, Robert L. Ferris, Curtis R. Pickering, Jing H. Wang, Ravi B. Patel, Heath D. Skinner
Publikováno v:
Cancers, Vol 16, Iss 8, p 1586 (2024)
The curative treatment of multiple solid tumors, including head and neck squamous cell carcinoma (HNSCC), utilizes radiation. The outcomes for HPV/p16-negative HNSCC are significantly worse than HPV/p16-positive tumors, with increased radiation resis
Externí odkaz:
https://doaj.org/article/4db4007c8f0f4ef7bda7222f9e858d99
Autor:
Manish Kumar, David Molkentine, Jessica Molkentine, Kathleen Bridges, Tongxin Xie, Liangpeng Yang, Andrew Hefner, Meng Gao, Reshub Bahri, Annika Dhawan, Mitchell J. Frederick, Sahil Seth, Mohamed Abdelhakiem, Beth M. Beadle, Faye Johnson, Jing Wang, Li Shen, Timothy Heffernan, Aakash Sheth, Robert L. Ferris, Jeffrey N. Myers, Curtis R. Pickering, Heath D. Skinner
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Mutations in histone acetyltransferases (HATs) CREBBP and EP300 are generally thought to lead to decreased function or absence of protein product. Here the authors describe a gain of function of several CREBBP mutations leading to baseline hyper-acet
Externí odkaz:
https://doaj.org/article/9e9b057abf944363949c648ff88a38f3
Autor:
Phillip M. Pifer, Liangpeng Yang, Manish Kumar, Tongxin Xie, Mitchell Frederick, Andrew Hefner, Beth Beadle, David Molkentine, Jessica Molkentine, Annika Dhawan, Mohamed Abdelhakiem, Abdullah A. Osman, Jeffrey N. Myers, Curtis R. Pickering, Vlad C. Sandulache, John Heymach, Heath D. Skinner
Radiation and platinum-based chemotherapy form the backbone of therapy in HPV-negative head and neck squamous cell carcinoma (HNSCC). We have correlated focal adhesion kinase (FAK/PTK2) expression with radioresistance and worse outcome in these patie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c32c70371d0c59e57aad6acc4e2bf0c
https://doi.org/10.1101/2022.06.03.494547
https://doi.org/10.1101/2022.06.03.494547
Autor:
Mohamed Abdelhakiem, Riyue Bao, Phillip M. Pifer, David Molkentine, Jessica Molkentine, Andrew Hefner, Beth M. Beadle, John Heymach, Jason J. Luke, Robert L. Ferris, Curtis Pickering, Jing H. Wang, Ravi B. Patel, Heath D. Skinner
Background Curative treatment of the most aggressive solid tumors utilizes radiation therapy, either as a monotherapy or combined with surgery and/or chemotherapy. Previously, we linked the expression of PD-L1 with clinical radioresistance; however,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2236d1e52710631f786e90be9fffa265
https://doi.org/10.21203/rs.3.rs-1537302/v2
https://doi.org/10.21203/rs.3.rs-1537302/v2
Autor:
Mohamed Abdelhakiem, Riyue Bao, Phillip M. Pifer, David Molkentine, Jessica Molkentine, Andrew Hefner, Beth M. Beadle, John Heymach, Jason J. Luke, Robert L. Ferris, Curtis Pickering, Jing H. Wang, Ravi B. Patel, Heath D. Skinner
Background Human papillomavirus (HPV)-negative head and neck squamous cell carcinoma (HNSCC) leads to the death of over 360,000 patients annually worldwide. Curative therapy for this disease commonly consists of surgery followed by radiation therapy.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d87928ac5e629786b10118c87b1be867
https://doi.org/10.21203/rs.3.rs-1537302/v1
https://doi.org/10.21203/rs.3.rs-1537302/v1