Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Andrew Hedger"'
Autor:
Md. Habibur Rahaman, Sara J. Thygesen, Michael J. Maxwell, Hyoyoung Kim, Prerna Mudai, Jeffrey D. Nanson, Xinying Jia, Parimala R. Vajjhala, Andrew Hedger, Irina Vetter, Thomas Haselhorst, Avril A. B. Robertson, Brian Dymock, Thomas Ve, Mehdi Mobli, Katryn J. Stacey, Bostjan Kobe
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 39, Iss 1 (2024)
AbstractToll-like receptor (TLR) innate immunity signalling protects against pathogens, but excessive or prolonged signalling contributes to a range of inflammatory conditions. Structural information on the TLR cytoplasmic TIR (Toll/interleukin-1 rec
Externí odkaz:
https://doaj.org/article/dcf8b7e19c924597be45dfa99851bf23
Autor:
Meryl Haas, Daniel F. Azar, Andrew Hedger, Tim Skern, Md. Habibur Rahaman, Sofiya Fedosyuk, Bostjan Kobe
Publikováno v:
Structure (London, England : 1993). 28(12)
Vaccinia virus A46 is an anti-inflammatory and non-anti-apoptotic, two-domain member of the poxviral Bcl-2-like protein family that inhibits the cellular innate immune response at the level of the Toll/interleukin-1 receptor (TIR) domain-containing T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ce9a28bb51f37576effa236ef8f2e43
https://pubmed.ncbi.nlm.nih.gov/33035450
https://pubmed.ncbi.nlm.nih.gov/33035450
Publikováno v:
Acta Crystallographica Section A Foundations and Advances. 77:C1111-C1111
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::52cafd82052f47ee2292560c2040aef0
https://doi.org/10.1107/s0108767321085949
https://doi.org/10.1107/s0108767321085949
Autor:
Frank DiMaio, Emma Sierecki, Peter Lavrencic, Katryn J. Stacey, Garry Morgan, Parimala R. Vajjhala, Ashley Mansell, Zahid Hassan, Tristan I. Croll, Xiong Yu, Edward H. Egelman, Michael J. Landsberg, Ailis O'Carroll, Thomas Ve, Andrew Hedger, S. Horsefield, Mehdi Mobli, Bostjan Kobe, Yann Gambin, Brieuc Chauvin
Publikováno v:
Nat Struct Mol Biol
Toll-like receptor (TLR) signaling is a key innate immunity response to pathogens. Recruitment of signaling adapters such as MAL (TIRAP) and MyD88 to the TLRs requires Toll/interleukin-1 receptor (TIR)-domain interactions, which remain structurally e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a54ed75a7f660ab6cc409bb6036397f
https://doi.org/10.1038/nsmb.3444
https://doi.org/10.1038/nsmb.3444