Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Andrew H. Park"'
Autor:
Young-Seung Kim, Bong-Ki Hong, Steven H Lin, Seung-Hoon Lee, Stephen S Yoo, Chunai Wu, Andrew H Park, Hyunjin Jung
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 3 (2024)
Background While Programmed cell death protein 1 (PD-1)/programmed cell death-ligand 1 (PD-L1) blockade is a potent antitumor treatment strategy, it is effective in only limited subsets of patients with cancer, emphasizing the need for the identifica
Externí odkaz:
https://doaj.org/article/c59cf4b5ca514115b9cf3aad5938038e
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/bbf912e6211a4faebd3d86d0a12c7eb9
Publikováno v:
Molecular Cancer Therapeutics. 20:LBA019-LBA019
Butyrophilin (BTN) proteins are members of the B7 immunoglobulin superfamily and exhibit well-characterized immunomodulatory functions in mammals. We have recently identified BTN1A1 as an immune checkpoint protein prominently upregulated in response
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::95463dc4373ef5c842a258168588bd39
https://doi.org/10.1158/1535-7163.targ-21-lba019
https://doi.org/10.1158/1535-7163.targ-21-lba019
Abstract 1643: BTN1A1: a novel immune checkpoint for cancer immunotherapy beyond the PD-1/PD-L1 axis
Autor:
Young-Ok You, Yong-Sik Bong, Ezra M. Chung, Young-Joon Lee, Stephen S. Yoo, Andrew H. Park, Hyunjin Jung, Steven H. Lin, Young-Seung Kim, Amrish Sharma
Publikováno v:
Cancer Research. 81:1643-1643
Cancer immunotherapy is an effective treatment against individuals with late-stage cancer forms. The PD-1/PD-LI axis is a main therapeutic target used in clinical settings, but only 15-20% of cancer patients are responsive. Thus, there is an urgent u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5597724238b7663363d7c5021f25afa7
https://doi.org/10.1158/1538-7445.am2021-1643
https://doi.org/10.1158/1538-7445.am2021-1643
Autor:
Jielin Liu, Li Chuan Chan, Kay-Hooi Khoo, Yi Yang, Kim Yong Soo, Yun-Ju Lai, Jong Ho Cha, Heng Huan Lee, Stephen S. Yoo, Andrew H. Park, Chia Wei Li, Ri Yao Yang, Jennifer L. Hsu, Mien Chie Hung, Jun Yao, Jung-Mao Hsu, Linlin Sun, Yu Han Wang, Ezra M. Chung, Yufan Qiu
Publikováno v:
Cancer Res
Immunotherapies targeting programmed cell death protein 1 (PD-1) and programmed cell death 1 ligand 1 (PD-L1) immune checkpoints represent a major breakthrough in cancer treatment. PD-1 is an inhibitory receptor expressed on the surface of activated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5e3d1c0daee6ffacdc25d9a0f08fa0a
https://pubmed.ncbi.nlm.nih.gov/32156778
https://pubmed.ncbi.nlm.nih.gov/32156778
Autor:
Kristin N. Bales, Andrew H. Park, Cynthia M. Dupureur, Jacquelyn Niederschulte, James K. Bashkin, Yang Song
Publikováno v:
Biochimie. 165
The interactions of 6–8 ring hairpin polyamides (PAs) with the minor groove of DNA have been investigated extensively. More recent studies of large antiviral PAs (14–20 rings) active against small DNA tumor viruses lead to questions regarding the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c40b3aa35e0965f6aaebeb524ed2dc9c
https://pubmed.ncbi.nlm.nih.gov/31376420
https://pubmed.ncbi.nlm.nih.gov/31376420
Autor:
Jung-Mao Hsu, Yufan Qiu, Yu-Han Wang, Yi Yang, Kay-Hooi Khoo, Yongsoo Kim, Mien Chie Hung, Jong Ho Cha, Chia Wei Li, Linlin Sun, Jennifer L. Hsu, Li Chuan Chan, Andrew H. Park, Yun-Ju Lai, Ezra M. Chung, Stephen S. Yoo, Ri Yao Yang, Jielin Liu, Heng Huan Lee
Publikováno v:
Cancer Research. 80:6527-6527
Immunotherapy targeting programmed cell death protein 1 (PD-1) and programmed cell death 1 ligand 1 (PD-L1) immune checkpoints represents a major breakthrough in cancer treatment. PD-1 is an inhibitory receptor expressed on the surface of activated T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac5ecbfed22d8abb781129a06d0b5b41
https://doi.org/10.1158/1538-7445.am2020-6527
https://doi.org/10.1158/1538-7445.am2020-6527
Autor:
Biagio Ricciuti, Mark M. Awad, Julia E. Rudolph, Jocelyn Lee, Andrew H. Park, Valsamo Anagnostou, Gregory J. Riely, Robert B. Scharpf, Michele LeNoue-Newton, Leon Raskin, Christine M. Lovly
Publikováno v:
Cancer Research. 80:1095-1095
The RAS family of small GTPases represents the most commonly activated oncogenes and mutations in KRAS, NRAS and HRAS are found in approximately one third of all human cancers. To better understand the prevalence of somatic RAS mutations and the comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8bcf60c9d4e024bda76286ef6555c703
https://doi.org/10.1158/1538-7445.am2020-1095
https://doi.org/10.1158/1538-7445.am2020-1095
Autor:
Kay-Hooi Khoo, Shih Shin Chang, Kim Yong Soo, Chia Wei Li, Taewan Kim, Ezra M. Chung, Jennifer L. Hsu, Jong Ho Cha, Aysegul A. Sahin, Yen-Liang Liu, Andrew H. Park, Chu Wei Kuo, Jun Yao, Gabriel N. Hortobagyi, Weiya Xia, Tzu Hsuan Huang, Chao Kai Chou, Hirohito Yamaguchi, Yun Wu, Evan P. Perillo, Jung Mao Hsu, Hsin-Chih Yeh, Stephen S. Yoo, Li Chuan Chan, Andrew K. Dunn, Seung Oe Lim, Heng Huan Lee, Mien Chie Hung
Publikováno v:
Cancer cell. 33(2)
Summary Protein glycosylation provides proteomic diversity in regulating protein localization, stability, and activity; it remains largely unknown whether the sugar moiety contributes to immunosuppression. In the study of immune receptor glycosylatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27c9cfcdd8b9221d3c60d7004638e613
https://pubmed.ncbi.nlm.nih.gov/29438689
https://pubmed.ncbi.nlm.nih.gov/29438689
Publikováno v:
The Plant Journal. 50:1035-1048
Vascular plants evolved to have xylem that provides physical support for their growing body and serves as a conduit for water and nutrient transport. In a previous study, we used comparative-transcriptome analyses to select a group of genes that were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e3ff39187fa21598c27db25e5f720de
https://doi.org/10.1111/j.1365-313x.2007.03109.x
https://doi.org/10.1111/j.1365-313x.2007.03109.x