Zobrazeno 1 - 10
of 562
pro vyhledávání: '"Andrew H. -J. Wang"'
Autor:
Mu-Rong Kao, Hsion-Wen Kuo, Cheng-Chung Lee, Kuan-Ying Huang, Ting-Yen Huang, Chen-Wei Li, C. Will Chen, Andrew H. -J. Wang, Su-May Yu, Tuan-Hua David Ho
Publikováno v:
Biotechnology for Biofuels, Vol 12, Iss 1, Pp 1-18 (2019)
Abstract Background To produce second-generation biofuels, enzymatic catalysis is required to convert cellulose from lignocellulosic biomass into fermentable sugars. β-Glucosidases finalize the process by hydrolyzing cellobiose into glucose, so the
Externí odkaz:
https://doaj.org/article/eab72344d21b454fb98a6273e6e70902
Autor:
Jung-Chun Chu, Hui-Ju Tseng, Sung-Bau Lee, Kai-Cheng Hsu, Ling-Wei Hsin, Ru-Hao Liang, Tony Eight Lin, Nain-Chu Gao, Liang-Chieh Chen, Wan-Hsun Lu, Andrew H.-J Wang, Wei-Jan Huang
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1 (2023)
Class II histone deacetylases (HDACs) are considered as potential targets to treat Alzheimer’s disease (AD). Previously, C-3 substituted phenothiazine-containing compounds with class II HDAC-inhibiting activities was found to promote neurite outgro
Externí odkaz:
https://doaj.org/article/7b58580986544041963eeb2da4256825
Autor:
Cheng-Chung Lee, Yu-Cheng Su, Tzu-Ping Ko, Li-Ling Lin, Chih-Ya Yang, Stanley Shi-Chung Chang, Steve R. Roffler, Andrew H.-J. Wang
Publikováno v:
Journal of Biomedical Science, Vol 27, Iss 1, Pp 1-13 (2020)
Abstract Background Polyethylene glycol (PEG) is widely used in industry and medicine. Anti-PEG antibodies have been developed for characterizing PEGylated drugs and other applications. However, the underlying mechanism for specific PEG binding has n
Externí odkaz:
https://doaj.org/article/51050d5c634946ccafb198fd1f73c742
Autor:
Zu-Chian Chiang, Yi-Kai Chiu, Cheng-Chung Lee, Nai-Shu Hsu, Yueh-Liang Tsou, Hong-Sen Chen, Horng-Ru Hsu, Tzung-Jie Yang, An-Suei Yang, Andrew H-J Wang
Publikováno v:
PLoS ONE, Vol 15, Iss 9, p e0239813 (2020)
Two systems of antibody-drug conjugates (ADCs), noncleavable H32-DM1 and cleavable H32-VCMMAE, were developed by using different linkers and drugs attached to the anti-HER2 antibody H32, which is capable of cell internalization. Activated functional
Externí odkaz:
https://doaj.org/article/5d6f3f7fe5e14ac4956c0545a6f64839
Autor:
Meng‐Hsuan Wu, Cheng‐Chung Lee, An‐Shan Hsiao, Su‐May Yu, Andrew H.‐J. Wang, Tuan‐Hua David Ho
Publikováno v:
FEBS Open Bio, Vol 8, Iss 8, Pp 1230-1246 (2018)
A high‐efficiency laccase, DLac, was isolated from Cerrena sp. RSD1. The kinetic studies indicate that DLac is a diffusion‐limited enzyme. The crystal structure of DLac was determined to atomic resolution, and its overall structure shares high ho
Externí odkaz:
https://doaj.org/article/7cb7cac5457f474eb8a364426d1037f1
Autor:
Chih-Chuang Liaw, Li-Hua Lo, Tien-Hsing Cheng, Yuen Ting Chan, Yu-Ru Huang, Andrew H.-J. Wang, Hsin-Yang Chang
Publikováno v:
Organic Letters. 24:3281-3285
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d66894d7134d272f8cf150d999ca0e0
https://doi.org/10.1021/acs.orglett.2c01178
https://doi.org/10.1021/acs.orglett.2c01178
Autor:
Cheng-Chung Lee, Andrew H.-J. Wang, Po-Jung Pao, Ming-Hui Chiang, Min-Feng Hsu, Chun-Ting Chen
Publikováno v:
The FEBS Journal. 289:730-747
Specific antibody interactions with short peptides have made epitope tagging systems a vital tool employed in virtually all fields of biological research. Here, we present a novel epitope tagging system comprised of a monoclonal antibody named GD-26,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3016402348620492af1d45fb76a9828b
https://doi.org/10.1111/febs.16184
https://doi.org/10.1111/febs.16184
Autor:
Bo-Lin Lin, Chin-Yu Chen, Chun-Hsiang Huang, Tzu-Ping Ko, Cheng-Hung Chiang, Kuan-Fu Lin, Yuan-Chih Chang, Po-Yen Lin, Hui-Hsu Gavin Tsai, Andrew H-J Wang
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0169627 (2017)
The Sso7c4 from Sulfolobus solfataricus forms a dimer, which is believed to function as a chromosomal protein involved in genomic DNA compaction and gene regulation. Here, we present the crystal structure of wild-type Sso7c4 at a high resolution of 1
Externí odkaz:
https://doaj.org/article/439df130697948a2a8813a858eafbb12
Publikováno v:
ACS Omega
ACS Omega, Vol 6, Iss 7, Pp 4708-4718 (2021)
ACS Omega, Vol 6, Iss 7, Pp 4708-4718 (2021)
The formation of succinimide in proteins has attracted considerable attention in protein aging and biopharmaceutical research. The succinimide formation occurs spontaneously in proteins and is prone to hydrolysis to yield aspartate and isoaspartate,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b647a0acf1b63207c05ae3fa178ea978
https://doi.org/10.1021/acsomega.0c05503
https://doi.org/10.1021/acsomega.0c05503
Publikováno v:
Biochemical and Biophysical Research Communications. 536:1-6
Bacterial wall teichoic acids (WTAs) are synthesized intracellularly and exported by a two-component transporter, TagGH, comprising the transmembrane and ATPase subunits TagG and TagH. Here the dimeric structure of the N-terminal domain of TagH (TagH
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::411254ae6ec121060eb3a1314073f9a6
https://doi.org/10.1016/j.bbrc.2020.12.028
https://doi.org/10.1016/j.bbrc.2020.12.028