Zobrazeno 1 - 10
of 278
pro vyhledávání: '"Andrew H Beck"'
Autor:
Hanna Pulaski, Shraddha S Mehta, Laryssa C Manigat, Stephanie Kaufman, Hypatia Hou, ILKe Nalbantoglu, Xuchen Zhang, Emily Curl, Ross Taliano, Tae Hun Kim, Michael Torbenson, Jonathan N Glickman, Murray B Resnick, Neel Patel, Cristin E Taylor, Pierre Bedossa, Michael C Montalto, Andrew H Beck, Katy E Wack
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 10, Iss 5, Pp n/a-n/a (2024)
Abstract The gold standard for enrollment and endpoint assessment in metabolic dysfunction‐associated steatosis clinical trials is histologic assessment of a liver biopsy performed on glass slides. However, obtaining the evaluations from several ex
Externí odkaz:
https://doaj.org/article/eb1dc91a8f284aa1a624e1e8e3395dbb
Autor:
Alejandro Quiroz-Zárate, Benjamin J Harshfield, Rong Hu, Nick Knoblauch, Andrew H Beck, Susan E Hankinson, Vincent Carey, Rulla M Tamimi, David J Hunter, John Quackenbush, Aditi Hazra
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0170181 (2017)
We investigate 71 single nucleotide polymorphisms (SNPs) identified in meta-analytic studies of genome-wide association studies (GWAS) of breast cancer, the majority of which are located in intergenic or intronic regions. To explore regulatory impact
Externí odkaz:
https://doaj.org/article/7465f66e40e74eadaa5102485c208537
Autor:
Francisco Beca, Andrew H Beck
Publikováno v:
PLoS Medicine, Vol 13, Iss 12, p e1002177 (2016)
In a Perspective, Francisco Beca and Andrew Beck discuss Charles Swanton and colleagues' accompanying Research Article on somatic mutations in patients with inflammatory breast cancer treated in a Phase II clinical trial.
Externí odkaz:
https://doaj.org/article/f85943c8e4af4765b9b2cb5ca257abc7
Autor:
Andrew H Beck
Publikováno v:
PLoS Medicine, Vol 12, Iss 2, p e1001794 (2015)
In this guest editorial, Andrew Beck discusses the importance of open access to big data for translating knowledge of cancer heterogeneity into better outcomes for cancer patients.
Externí odkaz:
https://doaj.org/article/05883a5c1f4e41638c18331434d7831e
Autor:
Fei Dong, Humayun Irshad, Eun-Yeong Oh, Melinda F Lerwill, Elena F Brachtel, Nicholas C Jones, Nicholas W Knoblauch, Laleh Montaser-Kouhsari, Nicole B Johnson, Luigi K F Rao, Beverly Faulkner-Jones, David C Wilbur, Stuart J Schnitt, Andrew H Beck
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e114885 (2014)
The categorization of intraductal proliferative lesions of the breast based on routine light microscopic examination of histopathologic sections is in many cases challenging, even for experienced pathologists. The development of computational tools t
Externí odkaz:
https://doaj.org/article/844119d98e8d4658b32246632a97cbb3
Autor:
Andrew H Beck, Nicholas W Knoblauch, Marco M Hefti, Jennifer Kaplan, Stuart J Schnitt, Aedin C Culhane, Markus S Schroeder, Thomas Risch, John Quackenbush, Benjamin Haibe-Kains
Publikováno v:
PLoS Computational Biology, Vol 9, Iss 1, p e1002875 (2013)
A major goal in translational cancer research is to identify biological signatures driving cancer progression and metastasis. A common technique applied in genomics research is to cluster patients using gene expression data from a candidate prognosti
Externí odkaz:
https://doaj.org/article/187e8afad48645ac95fed262a6ca1d49
Autor:
Rinath M Jeselsohn, Lillian Werner, Meredith M Regan, Aquila Fatima, Lauren Gilmore, Laura C Collins, Andrew H Beck, Shannon T Bailey, Housheng Hansen He, Gilles Buchwalter, Myles Brown, J Dirk Iglehart, Andrea Richardson, Steven E Come
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e64225 (2013)
Advancements in molecular biology have unveiled multiple breast cancer promoting pathways and potential therapeutic targets. Large randomized clinical trials remain the ultimate means of validating therapeutic efficacy, but they require large cohorts
Externí odkaz:
https://doaj.org/article/0167b02320db44619be2f68bca433504
Autor:
Andrew H Beck, Ziming Weng, Daniela M Witten, Shirley Zhu, Joseph W Foley, Phil Lacroute, Cheryl L Smith, Robert Tibshirani, Matt van de Rijn, Arend Sidow, Robert B West
Publikováno v:
PLoS ONE, Vol 5, Iss 1, p e8768 (2010)
Gene expression microarrays are the most widely used technique for genome-wide expression profiling. However, microarrays do not perform well on formalin fixed paraffin embedded tissue (FFPET). Consequently, microarrays cannot be effectively utilized
Externí odkaz:
https://doaj.org/article/4b188761151c4748a7d11746f8c8cdb2
Autor:
Cheng-Han Lee, Subbaya Subramanian, Andrew H Beck, Inigo Espinosa, Janine Senz, Shirley X Zhu, David Huntsman, Matt van de Rijn, C Blake Gilks
Publikováno v:
PLoS ONE, Vol 4, Iss 10, p e7314 (2009)
BACKGROUND:MicroRNAs (miRNA) are 20 approximately 25 nucleotide non-coding RNAs that inhibit the translation of targeted mRNA, and they have been implicated in the development of human malignancies. High grade serous ovarian carcinomas, the most comm
Externí odkaz:
https://doaj.org/article/d007514a090443cc993d76c0554415d7
Autor:
John Abel, Christian Kirkup, Filip Kos, Ylaine Gerardin, Sandhya Srinivasan, Jacqueline Brosnan-Cashman, Ken Leidal, Sanjana Vasudevan, Deepta Rajan, Suyog Jain, Aaditya Prakash, Harshith Padigela, Jake Conway, Neel Patel, Benjamin Trotter, Limin Yu, Amaro Taylor-Weiner, Emma L. Krause, Matthew Bronnimann, Laura Chambre, Ben Glass, Chintan Parmar, Stephanie Hennek, Archit Khosla, Murray Resnick, Andrew H. Beck, Michael Montalto, Fedaa Najdawi, Michael G. Drage, Ilan Wapinski
Publikováno v:
Cancer Research. 83:P4-09
Background: Morphological features of cancer cell nuclei are routinely used to assess disease severity and prognosis, and cancer nuclear morphology has been linked to genomic alterations. Quantitative analyses of the nuclear features of cancer cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e46cbcad1f37fe7eb9010d40aed9af4
https://doi.org/10.1158/1538-7445.sabcs22-p4-09-08
https://doi.org/10.1158/1538-7445.sabcs22-p4-09-08