Zobrazeno 1 - 10
of 138
pro vyhledávání: '"Andrew G. Horti"'
Autor:
Catherine A. Foss, Ravi Naik, Deepankar Das, Hyojin Cha, Il Minn, Andrew Hall, Paige Finley, Sophia Jiang Wu, Yong Du, Robert F. Dannals, Martin G. Pomper, Andrew G. Horti
Publikováno v:
EJNMMI Research, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Background Reactive microglia and recruited peripheral macrophages contribute to the pathogenesis of Alzheimer’s dementia (AD). Monocytes, macrophages and microglia all express the marker colony-stimulating factor 1 receptor (CSF1R). 4-Cya
Externí odkaz:
https://doaj.org/article/ff0a8477f87b447c94ffbf280583166c
Autor:
Jennifer M. Coughlin, Yong Du, Wojciech G. Lesniak, Courtney K. Harrington, Mary Katherine Brosnan, Riley O’Toole, Adeline Zandi, Shannon Eileen Sweeney, Rehab Abdallah, Yunkou Wu, Daniel P. Holt, Andrew W. Hall, Robert F. Dannals, Lilja Solnes, Andrew G. Horti, Martin G. Pomper
Publikováno v:
EJNMMI Research, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract Purpose Study of the contribution of microglia to onset and course of several neuropsychiatric conditions is challenged by the fact that these resident immune cells often take on different phenotypes and functions outside the living brain. I
Externí odkaz:
https://doaj.org/article/76ad44458537447c9f4f54f7ef2310a0
Autor:
Yong Du, Il Minn, Catherine Foss, Wojciech G. Lesniak, Feng Hu, Robert F. Dannals, Martin G. Pomper, Andrew G. Horti
Publikováno v:
EJNMMI Research, Vol 10, Iss 1, Pp 1-12 (2020)
Abstract Purpose Soluble epoxide hydrolase (sEH) is a promising candidate positron emission tomography (PET) imaging biomarker altered in various disorders, including vascular cognitive impairment (VCI), Alzheimer’s disease (AD), Parkinson’s dise
Externí odkaz:
https://doaj.org/article/e7c8b691e87349a285de9b14fa0975b5
Autor:
Jordi Bonaventura, Mark A. G. Eldridge, Feng Hu, Juan L. Gomez, Marta Sanchez-Soto, Ara M. Abramyan, Sherry Lam, Matthew A. Boehm, Christina Ruiz, Mitchell R. Farrell, Andrea Moreno, Islam Mustafa Galal Faress, Niels Andersen, John Y. Lin, Ruin Moaddel, Patrick J. Morris, Lei Shi, David R. Sibley, Stephen V. Mahler, Sadegh Nabavi, Martin G. Pomper, Antonello Bonci, Andrew G. Horti, Barry J. Richmond, Michael Michaelides
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Designer Receptors Exclusively Activated by Designer Drugs (DREADDs) are a powerful tool for neuroscience, but the standard DREADD ligand, CNO, has significant drawbacks. Here the authors report two novel high-potency DREADD ligands and a novel DREAD
Externí odkaz:
https://doaj.org/article/61041765c18b4742add3c9f64f5d7580
Publikováno v:
Neurobiology of Disease, Vol 131, Iss , Pp - (2019)
With the movement toward precision medicine in healthcare, recent studies of individuals with psychosis have begun to explore positron emission tomography (PET) as a tool to test for biochemical signatures that may distinguish subtypes of psychosis t
Externí odkaz:
https://doaj.org/article/06092bd67ec044169328aca5231ee83e
Autor:
Cornelius K. Donat, Henrik H. Hansen, Hanne D. Hansen, Ronnie C. Mease, Andrew G. Horti, Martin G. Pomper, Elina T. L’Estrade, Matthias M. Herth, Dan Peters, Gitte M. Knudsen, Jens D. Mikkelsen
Publikováno v:
Molecules, Vol 25, Iss 6, p 1425 (2020)
The α7 nicotinic acetylcholine receptor (α7 nAChR) is involved in several cognitive and physiologic processes; its expression levels and patterns change in neurologic and psychiatric diseases, such as schizophrenia and Alzheimer’s disease, which
Externí odkaz:
https://doaj.org/article/efc1f66ada2543bca63ea2541a8178d8
Publikováno v:
Molecules, Vol 22, Iss 1, p 77 (2017)
A small series of indol-3-yl-oxoacetamides was synthesized starting from the literature known N-(adamantan-1-yl)-2-(5-(furan-2-yl)-1-pentyl-1H-indol-3-yl)-2-oxoacetamide (5) by substituting the 1-pentyl-1H-indole subunit. Our preliminary biological e
Externí odkaz:
https://doaj.org/article/9f13e86df1ab49ba80b44a096be65f77
Autor:
Catherine A. Foss, Alvaro A. Ordonez, Ravi Naik, Deepankar Das, Andrew Hall, Yunkou Wu, Robert F. Dannals, Sanjay K. Jain, Martin G. Pomper, Andrew G. Horti
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging. 49:4088-4096
Macrophages represent an essential means of sequestration and immune evasion for Mycobacterium tuberculosis. Pulmonary tuberculosis (TB) is characterized by dense collections of tissue-specific and recruited macrophages, both of which abundantly expr
Autor:
Leah H. Rubin, Yong Du, Shannon Eileen Sweeney, Riley O’Toole, Courtney K. Harrington, Katelyn Jenkins, Wojciech G. Lesniak, Rebecca T. Veenhuis, Raha Dastgheyb, Joan Severson, Hong Fan, Daniel P. Holt, Andrew W. Hall, Robert F. Dannals, Andrew G. Horti, Martin G. Pomper, Jennifer M. Coughlin
Publikováno v:
AIDS.
Autor:
Yong Du, Jennifer M. Coughlin, Mary Katherine Brosnan, Allen Chen, Laura K. Shinehouse, Rehab Abdallah, Martin A. Lodge, William B. Mathews, Chen Liu, Yunkou Wu, Il Minn, Paige Finley, Andrew W. Hall, Wojciech G. Lesniak, Robert F. Dannals, Andrew G. Horti, Martin G. Pomper
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging.