The Molecular Basis for Zinc Bioavailability

Autor: Andrew G. Hall, Janet C. King

Publikováno v: International Journal of Molecular Sciences, Vol 24, Iss 7, p 6561 (2023)

Zinc is an essential micronutrient, and its deficiency is perhaps the most prevalent and least understood worldwide. Recent advances have expanded the understanding of zinc’s unique chemistry and molecular roles in a vast array of critical function

Externí odkaz: https://doaj.org/article/21a86bb801ff4fa88d7f82adef05cfbc

Genome-wide association analysis implicates dysregulation of immunity genes in chronic lymphocytic leukaemia

Autor: Philip J. Law, Sonja I. Berndt, Helen E. Speedy, Nicola J. Camp, Georgina P. Sava, Christine F. Skibola, Amy Holroyd, Vijai Joseph, Nicola J. Sunter, Alexandra Nieters, Silvia Bea, Alain Monnereau, David Martin-Garcia, Lynn R. Goldin, Guillem Clot, Lauren R. Teras, Inés Quintela, Brenda M. Birmann, Sandrine Jayne, Wendy Cozen, Aneela Majid, Karin E. Smedby, Qing Lan, Claire Dearden, Angela R. Brooks-Wilson, Andrew G. Hall, Mark P. Purdue, Tryfonia Mainou-Fowler, Claire M. Vajdic, Graham H. Jackson, Pierluigi Cocco, Helen Marr, Yawei Zhang, Tongzhang Zheng, Graham G. Giles, Charles Lawrence, Timothy G. Call, Mark Liebow, Mads Melbye, Bengt Glimelius, Larry Mansouri, Martha Glenn, Karen Curtin, W Ryan Diver, Brian K. Link, Lucia Conde, Paige M. Bracci, Elizabeth A. Holly, Rebecca D. Jackson, Lesley F. Tinker, Yolanda Benavente, Paolo Boffetta, Paul Brennan, Marc Maynadie, James McKay, Demetrius Albanes, Stephanie Weinstein, Zhaoming Wang, Neil E. Caporaso, Lindsay M. Morton, Richard K. Severson, Elio Riboli, Paolo Vineis, Roel C. H. Vermeulen, Melissa C. Southey, Roger L. Milne, Jacqueline Clavel, Sabine Topka, John J. Spinelli, Peter Kraft, Maria Grazia Ennas, Geoffrey Summerfield, Giovanni M. Ferri, Robert J. Harris, Lucia Miligi, Andrew R. Pettitt, Kari E. North, David J. Allsup, Joseph F. Fraumeni, James R. Bailey, Kenneth Offit, Guy Pratt, Henrik Hjalgrim, Chris Pepper, Stephen J. Chanock, Chris Fegan, Richard Rosenquist, Silvia de Sanjose, Angel Carracedo, Martin J. S. Dyer, Daniel Catovsky, Elias Campo, James R. Cerhan, James M. Allan, Nathanial Rothman, Richard Houlston, Susan Slager

Publikováno v: Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)

Chronic lymphocytic leukaemia has a hereditary component, much of which remains to be identified. Here, the authors perform a genome-wide association study and find new risk loci for the disease, which are associated with genes involved in immune fun

Externí odkaz: https://doaj.org/article/7260f008ee8e4abd981c7eed2433bb15

Data from Mutation of Genes Affecting the RAS Pathway Is Common in Childhood Acute Lymphoblastic Leukemia

Autor: Julie A.E. Irving, Andrew G. Hall, Josef Vormoor, Simon Bailey, Nick Bown, Christine J. Harrison, Rosline Hassan, Lynne Minto, Elizabeth Matheson, Marian Case

Deregulation of the RAS-RAF-mitogen-activated protein kinase/extracellular signal-regulated kinase (ERK) kinase (MEK)-ERK signaling cascade is often caused by somatic mutations in genes encoding proteins which influence the activity of this pathway a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fee3ab4b4c8826af7c0cd1260b59b67
https://doi.org/10.1158/0008-5472.c.6496418

Supplementary Table 2 from Mutation of Genes Affecting the RAS Pathway Is Common in Childhood Acute Lymphoblastic Leukemia

Autor: Julie A.E. Irving, Andrew G. Hall, Josef Vormoor, Simon Bailey, Nick Bown, Christine J. Harrison, Rosline Hassan, Lynne Minto, Elizabeth Matheson, Marian Case

Supplementary Table 2 from Mutation of Genes Affecting the RAS Pathway Is Common in Childhood Acute Lymphoblastic Leukemia

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0da64287d43e2de90fbb17df16c0dfed
https://doi.org/10.1158/0008-5472.22370489.v1

Supplementary Table 4 from Mutation of Genes Affecting the RAS Pathway Is Common in Childhood Acute Lymphoblastic Leukemia

Autor: Julie A.E. Irving, Andrew G. Hall, Josef Vormoor, Simon Bailey, Nick Bown, Christine J. Harrison, Rosline Hassan, Lynne Minto, Elizabeth Matheson, Marian Case

Supplementary Table 4 from Mutation of Genes Affecting the RAS Pathway Is Common in Childhood Acute Lymphoblastic Leukemia

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fcc9857434fac6c0b69dedf1db505aa
https://doi.org/10.1158/0008-5472.22370483