Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Andrew G. Gillard"'
Publikováno v:
Molecular Oncology, Vol 18, Iss 4, Pp 781-784 (2024)
Oncolytic viruses (OVs) are biological therapeutic agents that selectively destroy cancer cells while sparing normal healthy cells. Besides direct oncolysis, OV infection induces a proinflammatory shift in the tumor microenvironment and the release o
Externí odkaz:
https://doaj.org/article/f196420c54cc4f3dabd5e868f56a064a
Autor:
Andrew G. Gillard, Dong Ho Shin, Lethan A. Hampton, Andres Lopez-Rivas, Akhila Parthasarathy, Juan Fueyo, Candelaria Gomez-Manzano
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 2, p 947 (2024)
Currently, there is a lack of effective therapies for the majority of glioblastomas (GBMs), the most common and malignant primary brain tumor. While immunotherapies have shown promise in treating various types of cancers, they have had limited succes
Externí odkaz:
https://doaj.org/article/87e1f908e9164d93abd7fef33949545b
Autor:
Juan Fueyo, Candelaria Gomez-Manzano, Frederick F. Lang, Andrew G. Gillard, Jiasen He, Joy Gumin, Xuejun Fan, Yanhua Yi, Dong Ho Shin, Hong Jiang
Survival plots of mice with s.c./s.c. melanomas treated with PBS or wildtype (WT) CD8+ T cells injected into the s.c. Tumor 1. PBS: n=8; WT CTLs: n=5. ns: not significant (p > 0.05). log-rank test.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::105501346a8af6818d6f75188c580d1a
https://doi.org/10.1158/2767-9764.22435861
https://doi.org/10.1158/2767-9764.22435861
Autor:
Juan Fueyo, Candelaria Gomez-Manzano, Frederick F. Lang, Andrew G. Gillard, Jiasen He, Joy Gumin, Xuejun Fan, Yanhua Yi, Dong Ho Shin, Hong Jiang
gp100 and ovalbumin (OVA) expression in indicated mouse melanoma cell lines. Cell lysates were analyzed with immunoblotting. GAPDH levels are shown as a protein loading control.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c0d6678ef943bbb9ef329761559bce3
https://doi.org/10.1158/2767-9764.22435867.v1
https://doi.org/10.1158/2767-9764.22435867.v1
Autor:
Juan Fueyo, Candelaria Gomez-Manzano, Frederick F. Lang, Andrew G. Gillard, Jiasen He, Joy Gumin, Xuejun Fan, Yanhua Yi, Dong Ho Shin, Hong Jiang
Expression of TCRs in CD8+ T cells from pmel-1 (A, gp100-Tet+) or OT-I (B, OVA-Tet+) transgenic mice. Splenocytes from the mice were stained with tetramers binding with TCR specific for gp100 (pmel-1) or OVA (OT-I), and antibody against CD8. Stained
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3eb743b481c4787cb481742b5a761f6
https://doi.org/10.1158/2767-9764.22435864.v1
https://doi.org/10.1158/2767-9764.22435864.v1
Autor:
Juan Fueyo, Candelaria Gomez-Manzano, Frederick F. Lang, Andrew G. Gillard, Jiasen He, Joy Gumin, Xuejun Fan, Yanhua Yi, Dong Ho Shin, Hong Jiang
Antibody information
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ad6c86af8fb8489e1e65fdbe759eb6b
https://doi.org/10.1158/2767-9764.22435849.v1
https://doi.org/10.1158/2767-9764.22435849.v1
Autor:
Juan Fueyo, Candelaria Gomez-Manzano, Frederick F. Lang, Andrew G. Gillard, Jiasen He, Joy Gumin, Xuejun Fan, Yanhua Yi, Dong Ho Shin, Hong Jiang
The effect of combining pmel-1 T cells and Delta-24-RGDOX. A, A cartoon depiction of the treatment scheme for schedule (left) and positions of tumor implantation, T-cell and virus injection (right). s.c.: subcutaneously; i.t.: intratumorally. B, Plot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30a24fe05d4aa9ebaddea85eade25e06
https://doi.org/10.1158/2767-9764.22435858
https://doi.org/10.1158/2767-9764.22435858
Autor:
Hong Jiang, Dong Ho Shin, Yanhua Yi, Xuejun Fan, Joy Gumin, Jiasen He, Andrew G. Gillard, Frederick F. Lang, Candelaria Gomez-Manzano, Juan Fueyo
Publikováno v:
Cancer Research Communications.
Cancer cell heterogeneity and immunosuppressive tumor microenvironment (TME) pose a challenge in treating solid tumors with adoptive cell therapies targeting limited tumor-associated antigens (TAAs), such as CAR T-cell therapy. We hypothesize that on
Autor:
Juan Fueyo, Candelaria Gomez-Manzano, Frederick F. Lang, Andrew G. Gillard, Jiasen He, Joy Gumin, Xuejun Fan, Yanhua Yi, Dong Ho Shin, Hong Jiang
Cancer cell heterogeneity and immunosuppressive tumor microenvironment (TME) pose a challenge in treating solid tumors with adoptive cell therapies targeting limited tumor-associated antigens (TAAs), such as CAR T-cell therapy. We hypothesize that on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20cd1e2c17fe070cb20839cbef039e98
https://doi.org/10.1158/2767-9764.c.6515128.v1
https://doi.org/10.1158/2767-9764.c.6515128.v1
Autor:
Hong Jiang, Frederick Lang, Juan Fueyo, Dong Ho Shin, Marta Alonso, Virginia Laspidea, Xuejun Fan, Andrew G Gillard, Jiasen He, Andres Lopez-Rivas, Akhila Parthasarathy, Candelaria Gomez Manzano
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/6eb6a75a7a7d4d59bed72096b32b960e