Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Andrew G. DeMarco"'
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
IntroductionReversible protein phosphorylation is an abundant post-translational modification dynamically regulated by opposing kinases and phosphatases. Protein phosphorylation has been extensively studied in cell division, where waves of cyclin-dep
Externí odkaz:
https://doaj.org/article/b69505817aa0404796fdcd97197c3098
Autor:
Clinton A. Gabel, Zhuang Li, Andrew G. DeMarco, Ziguo Zhang, Jing Yang, Mark C. Hall, David Barford, Leifu Chang
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
The eight-subunit augmin complex is required to nucleate branching microtubules and create a robust mitotic spindle during cell division. Here, the authors use cryo-EM, crosslinking mass spectrometry, and computational tools to build a structural mod
Externí odkaz:
https://doaj.org/article/21dc5e7397464617b4ce405536bc7e4b
Autor:
Kedric L. Milholland, Ahmed AbdelKhalek, Kortany M. Baker, Smriti Hoda, Andrew G. DeMarco, Noelle H. Naughton, Angela N. Koeberlein, Gabrielle R. Lorenz, Kartikan Anandasothy, Antonio Esperilla-Muñoz, Sanjeev K. Narayanan, Jaime Correa-Bordes, Scott D. Briggs, Mark C. Hall
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
The Cdc14 phosphatase family is highly conserved in fungi. In Saccharomyces cerevisiae, Cdc14 is essential for down-regulation of cyclin-dependent kinase activity at mitotic exit. However, this essential function is not broadly conserved and requires
Externí odkaz:
https://doaj.org/article/8648e86a4d7e443ca24a03550a6e2b25
Autor:
Andrew G. DeMarco, Mark C. Hall
Publikováno v:
Molecules, Vol 28, Iss 9, p 3675 (2023)
Protein phosphorylation is a ubiquitous post-translational modification controlled by the opposing activities of protein kinases and phosphatases, which regulate diverse biological processes in all kingdoms of life. One of the key challenges to a com
Externí odkaz:
https://doaj.org/article/2fdf4dcf468245c3af5cca6849db60b4
Autor:
Kedric L. Milholland, Ahmed AbdelKhalek, Kortany M. Baker, Smriti Hoda, Andrew G. DeMarco, Noelle H. Naughton, Angela N. Koeberlein, Gabrielle R. Lorenz, Kartikan Anandasothy, Antonio Esperilla-Muñoz, Sanjeev K. Narayanan, Jaime Correa-Bordes, Scott D. Briggs, Mark C. Hall
The Cdc14 phosphatase family is highly conserved in fungi. InSaccharomyces cerevisiae,Cdc14 is essential for down-regulation of cyclin-dependent kinase activity at mitotic exit. However, this essential function is not broadly conserved and requires a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2785420e30cab6244cb83e58e81eb35f
https://doi.org/10.1101/2022.09.29.510203
https://doi.org/10.1101/2022.09.29.510203
Autor:
Michael Girgis, Andrew G DeMarco, Kirandeep Gill, Sunil Bansal, Amrita K. Cheema, John B. Tyburski, Meth Jayatilake, Khyati Y. Mehta, Tixieanna Dissmore, Yaoxiang Li, Vijayalakshmi Sridharan, Shivani Bansal
Publikováno v:
J Environ Sci Health C Toxicol Carcinog
Astronauts embarking on deep space missions are at high risk of long-term exposure to low doses of high linear energy transfer (LET) radiation, which can contribute to the development of cancer and multiple degenerative diseases. However, long term e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67c1a0c351308ef21d95bcab9eed303e
https://doi.org/10.1080/26896583.2020.1865027
https://doi.org/10.1080/26896583.2020.1865027
Autor:
Kedric L. Milholland, Noelle H. Naughton, Andrew G. DeMarco, Kortany M. Baker, Scott D. Briggs, Jaime Correa‐Bordes, Mark C. Hall
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::342fc6c9e67f9e01080658a6e603f1ae
https://doi.org/10.1096/fasebj.2022.36.s1.r2437
https://doi.org/10.1096/fasebj.2022.36.s1.r2437
Autor:
Andrew G. DeMarco, Mark C. Hall
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b3c80f033e0b71e6a68de778fb6d3d45
https://doi.org/10.1096/fasebj.2022.36.s1.r2524
https://doi.org/10.1096/fasebj.2022.36.s1.r2524
Autor:
Der-Shyang Kao, Yanyan Du, Andrew G. DeMarco, Sehong Min, Mark C. Hall, Jean-Christophe Rochet, W. Andy Tao
Publikováno v:
Molecular & Cellular Proteomics. 21:100441
Hyperphosphorylation of the microtubule-associated protein Tau is a major hallmark of Alzheimer's disease and other tauopathies. Understanding the protein kinases that phosphorylate Tau is critical for the development of new drugs that target Tau pho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17376eb9196b57f099b992308f3e0172
https://doi.org/10.1016/j.mcpro.2022.100441
https://doi.org/10.1016/j.mcpro.2022.100441
Dissertation/ Thesis
Autor:
Andrew G. DeMarco (17103610)
Protein phosphorylation is a ubiquitous post-translational modification controlled by the opposing activities of protein kinases and phosphatases, which regulate diverse biological processes in all kingdoms of life. One of the key challenges to a com