Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Andrew G. Chambers"'
Autor:
Oliver Poetz, Adriana Aguilar-Mahecha, Yassene Mohammed, Mark Basik, Gerald Batist, Robert Popp, Cathy Lan, Andrew G. Chambers, Christoph H. Borchers, André LeBlanc, Huiyan Li
Publikováno v:
Analytical Chemistry, 89(19), 10592-10600
The phosphatidylinositol 3-kinase (PI3K)/protein kinase B (AKT)/mechanistic target of rapamycin (mTOR) pathway is one of the most commonly dysregulated signaling pathways that is linked to cancer development and progression, and its quantitative prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fa584bb5958191c8620c94dfdc269a1
https://doi.org/10.1021/acs.analchem.7b02934
https://doi.org/10.1021/acs.analchem.7b02934
Publikováno v:
Molecular & Cellular Proteomics. 14:3094-3104
The dried blood spot (DBS) methodology provides a minimally invasive approach to sample collection and enables room-temperature storage for most analytes. DBS samples have successfully been analyzed by liquid chromatography multiple reaction monitori
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97ad69fa1f8ae881aaecaed2c332322c
https://doi.org/10.1074/mcp.o115.049957
https://doi.org/10.1074/mcp.o115.049957
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. 1844:917-926
article i nfo Accurate and rapid protein quantitation is essential for screening biomarkers for disease stratification and monitoring, and to validate the hundreds of putative markers in human biofluids, including blood plasma. An analytical method t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85dc5d1c72d1e0ebed1844ca914bb24e
https://doi.org/10.1016/j.bbapap.2013.06.008
https://doi.org/10.1016/j.bbapap.2013.06.008
Publikováno v:
Expert Review of Proteomics. 10:567-578
Despite significant advances in treatment, cardiovascular disease (CVD) remains one of the leading causes of morbidity and mortality in developed and developing countries. Judicious monitoring of common risk factors has been unable to control this gl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac9a445583fb02db1d2514f0ca3d8119
https://doi.org/10.1586/14789450.2013.856763
https://doi.org/10.1586/14789450.2013.856763
Autor:
Julia M. Burkhart, Andrew J. Percy, Albert Sickmann, Christoph H. Borchers, Dominik Domanski, Angela M. Jackson, Juncong Yang, Andrew G. Chambers
Publikováno v:
Journal of Proteomics. 95:66-76
There exists a growing demand in the proteomics community to standardize experimental methods and liquid chromatography–mass spectrometry (LC/MS) platforms in order to enable the acquisition of more precise and accurate quantitative data. This nece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd408b5300f3fb69c71cf4a9795341f2
https://doi.org/10.1016/j.jprot.2013.07.026
https://doi.org/10.1016/j.jprot.2013.07.026
Publikováno v:
Journal of the American Society for Mass Spectrometry. 24:1338-1345
Dried blood spot (DBS) sampling methods are desirable for population-wide biomarker screening programs because of their ease of collection, transportation, and storage. Immunoassays are traditionally used to quantify endogenous proteins in these samp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be1ffd4242ff0413129d34f5e77599e3
https://doi.org/10.1007/s13361-013-0678-x
https://doi.org/10.1007/s13361-013-0678-x
Autor:
Juncong Yang, Andrew G. Chambers, Christoph H. Borchers, Alexander G. Camenzind, Andrew J. Percy
Publikováno v:
Molecular & Cellular Proteomics. 12:781-791
Dried blood spot (DBS) sampling, coupled with multiple reaction monitoring mass spectrometry (MRM-MS), is a well-established approach for quantifying a wide range of small molecule biomarkers and drugs. This sampling procedure is simpler and less-inv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10a66b9893e5671d6b4968090eec28b0
https://doi.org/10.1074/mcp.m112.022442
https://doi.org/10.1074/mcp.m112.022442
Autor:
Andrew J, Percy, Juncong, Yang, Andrew G, Chambers, Yassene, Mohammed, Tasso, Miliotis, Christoph H, Borchers
Publikováno v:
Advances in experimental medicine and biology. 919
Quantitative mass spectrometry (MS)-based approaches are emerging as a core technology for addressing health-related queries in systems biology and in the biomedical and clinical fields. In several 'omics disciplines (proteomics included), an approac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::65de776b33ff0c3e05973bbfafb3f4b7
https://pubmed.ncbi.nlm.nih.gov/27975233
https://pubmed.ncbi.nlm.nih.gov/27975233
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1410
Absolute quantitative strategies are emerging as a powerful and preferable means of deriving concentrations in biological samples for systems biology applications. Method development is driven by the need to establish new-and validate current-protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b799ebbd1c4dbf9dc25d54bbd2cdc28d
https://pubmed.ncbi.nlm.nih.gov/26867735
https://pubmed.ncbi.nlm.nih.gov/26867735
Publikováno v:
Methods in Molecular Biology ISBN: 9781493935222
Absolute quantitative strategies are emerging as a powerful and preferable means of deriving concentrations in biological samples for systems biology applications. Method development is driven by the need to establish new-and validate current-protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7bf71e4bccef9b3bbf0d1a0d42426567
https://doi.org/10.1007/978-1-4939-3524-6_1
https://doi.org/10.1007/978-1-4939-3524-6_1
