Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Andrew G Jarnicki"'
Autor:
Alison N Thorburn, Hsin-Yi Tseng, Chantal Donovan, Nicole G Hansbro, Andrew G Jarnicki, Paul S Foster, Peter G Gibson, Philip M Hansbro
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0156402 (2016)
BACKGROUND:Exposure to non-pathogenic Streptococcus pneumoniae and vaccination are inversely associated with asthma. Studies in animal models demonstrate that airway administration of S. pneumoniae (live or killed), or its vaccines or components, sup
Externí odkaz:
https://doaj.org/article/9082f3d2b79d4844b7c1b01afcf1a77c
Autor:
Michael Buchert, Dimitris Athineos, Helen E Abud, Zoe D Burke, Maree C Faux, Michael S Samuel, Andrew G Jarnicki, Catherine E Winbanks, Ian P Newton, Valerie S Meniel, Hiromu Suzuki, Steven A Stacker, Inke S Näthke, David Tosh, Joerg Huelsken, Alan R Clarke, Joan K Heath, Owen J Sansom, Matthias Ernst
Publikováno v:
PLoS Genetics, Vol 6, Iss 1, p e1000816 (2010)
Contributions of null and hypomorphic alleles of Apc in mice produce both developmental and pathophysiological phenotypes. To ascribe the resulting genotype-to-phenotype relationship unambiguously to the Wnt/beta-catenin pathway, we challenged the al
Externí odkaz:
https://doaj.org/article/c8728f803cb245d0b4062cdd15c9a522
Autor:
Natale Snape, Gary P. Anderson, Louis B. Irving, Andrew G. Jarnicki, Aeron C. Hurt, Tina Collins, Yang Xi, John W. Upham
Publikováno v:
npj Vaccines, Vol 7, Iss 1, Pp 1-8 (2022)
Abstract Though clinical guidelines recommend influenza vaccination for chronic obstructive pulmonary disease (COPD) patients and other high-risk populations, it is unclear whether current vaccination strategies induce optimal antibody responses. Thi
Externí odkaz:
https://doaj.org/article/459c635dd50f4d52aa55ff5c815182cf
Autor:
Markus Fleischmann, Andrew G. Jarnicki, Andrew S. Brown, Chao Yang, Gary P. Anderson, Natalio Garbi, Elizabeth L. Hartland, Ian R. van Driel, Garrett Z. Ng
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 324:L373-L384
Legionella pneumophila is the main etiological agent of Legionnaires’ disease, a severe bacterial pneumonia. L. pneumophila is initially engulfed by alveolar macrophages (AMs) and subvert normal cellular functions to establish a replicative vacuole
Autor:
Chantal Donovan, Richard Y Kim, Izabela Galvao, Andrew G Jarnicki, Alexandra C Brown, Bernadette Jones‐Freeman, Henry M Gomez, Ridhima Wadhwa, Elinor Hortle, Ranjith Jayaraman, Haroon Khan, Sophie Pickles, Priyanka Sahu, Vrushali Chimankar, Xiaofan Tu, Md Khadem Ali, Jemma R Mayall, Duc H Nguyen, Kurtis F Budden, Vinod Kumar, Kate Schroder, Avril AB Robertson, Matthew A Cooper, Peter AB Wark, Brian G Oliver, Jay C Horvat, Philip M Hansbro
Publikováno v:
Immunology & Cell Biology. 100:235-249
Increased inflammasome responses are strongly implicated in inflammatory diseases; however, their specific roles are incompletely understood. Therefore, we sought to examine the roles of nucleotide-binding oligomerization domain-like receptor (NLR) f
Autor:
Andrew G. Jarnicki, Andreas Strasser, Kirsten A. Fairfax, Sarah A. Best, Christina Nedeva, Kate D. Sutherland, Robyn L Schenk, Hamsa Puthalakath, Damian B D'Silva, Marco J Herold, Cynthia Louis, Lahiru Gangoda
Publikováno v:
Cell Death Differ
Inflammation is a natural defence mechanism of the body to protect against pathogens. It is induced by immune cells, such as macrophages and neutrophils, which are rapidly recruited to the site of infection, mediating host defence. The processes for
Autor:
Kevin M.-C. Lee, Christian Ellson, Andrew D. Cook, Maria Feeney, Adrian Achuthan, Andrew J. Fleetwood, John A. Hamilton, Louise K. Modis, Julia Smith, Andrew G. Jarnicki, Gary P. Anderson
Publikováno v:
The Journal of Immunology. 205:213-222
It has been reported that a GM-CSF→CCL17 pathway, originally identified in vitro in macrophage lineage populations, is implicated in the control of inflammatory pain, as well as arthritic pain and disease. We explore, in this study and in various i
Autor:
Robert J. J. O'Donoghue, Darryl A. Knight, Carl D. Richards, Cecilia M. Prêle, Hui Ling Lau, Andrew G. Jarnicki, Jessica Jones, Steven Bozinovski, Ross Vlahos, Stefan Thiem, Brent S. McKenzie, Bo Wang, Philip Stumbles, Geoffrey J. Laurent, Robin J. McAnulty, Stefan Rose‐John, Hong Jian Zhu, Gary P. Anderson, Matthias R. Ernst, Steven E. Mutsaers
Publikováno v:
EMBO Molecular Medicine, Vol 4, Iss 9, Pp 939-951 (2012)
Abstract Idiopathic pulmonary fibrosis (IPF) is a fatal disease that is unresponsive to current therapies and characterized by excessive collagen deposition and subsequent fibrosis. While inflammatory cytokines, including interleukin (IL)‐6, are el
Externí odkaz:
https://doaj.org/article/bc3bb7468c6647178e64c5cfbda37d78
Autor:
Andrew G. Jarnicki, Guy Brusselle, Philip M. Hansbro, Paul S. Foster, Peter A. B. Wark, Griet Conickx, Gaetano Caramori, Pieter Mestdagh, Fabio Lm Ricciardolo, Alan Hsu, Gang Liu, Krishna P. Sunkara, Emma L. Beckett, Sara R.A. Wijnant, Jay C. Horvat, Antonio Ieni, Izabela Galvão, Chantal Donovan, Richard Kim, Tatt Jhong Haw, Angela Ferguson, Antonino Di Stefano, Umamainthan Palendira, Ken R. Bracke
Publikováno v:
Science Translational Medicine. 13
Chronic obstructive pulmonary disease (COPD) is the third leading cause of morbidity and death worldwide. Inhalation of cigarette smoke (CS) is the major cause in developed countries. Current therapies have limited efficacy in controlling disease or
Autor:
Robert J.J. O'Donoghue, Gary P. Anderson, Caitlin O'Brien, Giuseppe D. Ciccotosto, Delaney Haugan, Mun Joo Chuei, Thomas Jaquin, Ellie H-J Cho, Goran Martic, Vanessa Welk, Andrew G. Jarnicki, Gabrielle Matschiner, Kathryn Stok
Publikováno v:
Mechanisms of lung injury and repair.