Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Andrew G, Hadley"'
Autor:
Andrew G. Hadley, Craig P. Turner
Publikováno v:
British Journal of Haematology. 121:623-631
Antibody-mediated platelet destruction is a poorly understood process, although several lines of evidence suggest that Fcgamma receptor (FcgammaR)-expressing splenic macrophages may be involved. In this study, chemiluminescence (CL) was used to measu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::622e41f16e98349c4cd6affc9b5dd93e
https://doi.org/10.1046/j.1365-2141.2003.04324.x
https://doi.org/10.1046/j.1365-2141.2003.04324.x
Autor:
Andrew G. Hadley
Publikováno v:
Transplant Immunology. 10:191-198
Haemolytic disease of the fetus and newborn (HDFN) is characterised by the presence of IgG antibodies in the maternal circulation which cause haemolysis in the fetus by crossing the placenta and sensitising red cells for destruction by macrophages in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac4097f7dd71f2e897c60b08b190af9e
https://doi.org/10.1016/s0966-3274(02)00065-5
https://doi.org/10.1016/s0966-3274(02)00065-5
Publikováno v:
European Journal of Immunology. 29:2613-2624
Subclasses of human IgG have a range of activity levels with different effector systems but each triggers at least one mechanism of cell destruction. We are aiming to engineer non-destructive human IgG constant regions for therapeutic applications wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21fa095fa6ceaab0b0bbc4a1a107818e
https://doi.org/10.1002/(sici)1521-4141(199908)29:08<2613::aid-immu2613>3.0.co
https://doi.org/10.1002/(sici)1521-4141(199908)29:08<2613::aid-immu2613>3.0.co
Autor:
David M. Penman, Anthony M. Wilkes, Jean Goodrick, Geoffrey Lucas, Andrew G. Hadley, Peter W. Soothill
Publikováno v:
BJOG: An International Journal of Obstetrics and Gynaecology. 105:231-234
The chemiluminescence test measures the ability of anti-D to sensitise red cells for recognition by monocytes. It predicts clinical outcome in haemolytic disease of the newborn with greater precision than quantification of anti-D levels by AutoAnalyz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56a4b6c7a4d46625248c7874a8299910
https://doi.org/10.1111/j.1471-0528.1998.tb10059.x
https://doi.org/10.1111/j.1471-0528.1998.tb10059.x
Publikováno v:
Acta Obstetricia et Gynecologica Scandinavica. 75:102-107
To investigate if the prediction of hemolytic disease of the newborn (HDN) in infants of RhD immunized women has been improved by introduction of AutoAnalyzer quantitation and may be further improved by the use of a functional assay.Manual antibody t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5904c46969ac8ea49e67196f77590e0
https://doi.org/10.3109/00016349609033299
https://doi.org/10.3109/00016349609033299
Autor:
Jeffrey A. Jones, R. Stamps, Clarissa Pilkington, Barbara Zupanska, R J Sokol, Andrew G. Hadley, Katherine A. Leader, Helen L. Griffiths, Belinda M. Kumpel, D J Booker
Publikováno v:
British Journal of Haematology. 91:587-594
Factors governing the functional activity of red cell autoantibodies are poorly defined. Here we report the presence of qualitative differences in the glycosylation of IgG autoantibodies which affect in vitro interactions with Fc gamma RIII. The foll
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d28705211892f62d314de50b2df725c8
https://doi.org/10.1111/j.1365-2141.1995.tb05352.x
https://doi.org/10.1111/j.1365-2141.1995.tb05352.x
Publikováno v:
Human Antibodies. 6:82-88
The contribution to IgG effector function of exposed galactose residues on the oligosaccharide chains in IgG has been tested experimentally. We studied a human monoclonal antibody (BRAD-5) to the Rh D blood group antigen. The preparation used contain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::962fdb6b9f9d765f7884566dc1196be8
https://doi.org/10.3233/hab-1995-6301
https://doi.org/10.3233/hab-1995-6301
Publikováno v:
Immunology Letters. 42:91-95
The functional activity of Fc gamma RIII on human K cells from peripheral blood was compared with that of Fc gamma RIII on peritoneal macrophages (PM) separated from the waste material of patients undergoing peritoneal dialysis. Fc gamma R function w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67fd7be199563e1605ba24db604ef29d
https://doi.org/10.1016/0165-2478(94)90041-8
https://doi.org/10.1016/0165-2478(94)90041-8
Autor:
Andrew G. Hadley, Belinda Mary Kumpel
Publikováno v:
Baillière's Clinical Haematology. 6:423-444
Recent insights into the structure-function relationship of IgG, the nature of Fc receptors and their interactions with antibodies, and the cellular mechanisms involved in the immune destruction of IgG-sensitized cells have all contributed to a fulle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d2bfc0ce443674f3208112749d1e613f
https://doi.org/10.1016/s0950-3536(05)80153-2
https://doi.org/10.1016/s0950-3536(05)80153-2
Autor:
Katherine A. Leader, Peter T. Klouda, Godfrey J. Laundy, Benjamin A. Bradley, Andrew G. Hadley, Adrian Smith
Publikováno v:
Immunology Letters. 27:215-220
A procedure for the detection of FcR-blocking alloantibodies is described which uses human B lymphocytes immobilised on plastic by poly-L-lysine. Antibodies which inhibited rosette formation between B lymphocytes or Daudi cells and ox erythrocytes co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffb0feec63092756d2f883725e83969b
https://doi.org/10.1016/0165-2478(91)90154-3
https://doi.org/10.1016/0165-2478(91)90154-3