Zobrazeno 1 - 10
of 225
pro vyhledávání: '"Andrew G, Elefanty"'
Autor:
Shicheng Sun, Ali Motazedian, Jacky Y. Li, Kevin Wijanarko, Joe Jiang Zhu, Kothila Tharmarajah, Kathleen A. Strumila, Anton Shkaruta, L. Rayburn Nigos, Jacqueline V. Schiesser, Yi Yu, Paul J. Neeson, Elizabeth S. Ng, Andrew G. Elefanty, Edouard G. Stanley
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Arterial endothelial cells (AECs) are the founder cells for intraembryonic haematopoiesis. Here, we report a method for the efficient generation of human haemogenic DLL4+ AECs from pluripotent stem cells (PSC). Time-series single-cell RNA-se
Externí odkaz:
https://doaj.org/article/6b789ce0af934d5d87158dc872de5c71
Autor:
Kiryu K. Yap, Jan Schröder, Yi-Wen Gerrand, Aleksandar Dobric, Anne M. Kong, Adrian M. Fox, Brett Knowles, Simon W. Banting, Andrew G. Elefanty, Eduoard G. Stanley, George C. Yeoh, Glen P. Lockwood, Victoria C. Cogger, Wayne A. Morrison, Jose M. Polo, Geraldine M. Mitchell
Publikováno v:
JHEP Reports, Vol 6, Iss 5, Pp 101023- (2024)
Background & Aims: Liver sinusoidal endothelial cells (LSECs) are important in liver development, regeneration, and pathophysiology, but the differentiation process underlying their tissue-specific phenotype is poorly understood and difficult to stud
Externí odkaz:
https://doaj.org/article/e8a0dc074d684146bd805a7e443ce74f
Autor:
Katerina Vlahos, Koula Sourris, Jia Yi Kuah, Alison Graham, Annabelle Suter, Sara E. Howden, Edouard G. Stanley, Andrew G. Elefanty
Publikováno v:
Stem Cell Research, Vol 69, Iss , Pp 103109- (2023)
We describe the generation and characterisation of five human induced pluripotent stem cell (iPSC) lines derived from peripheral blood mononuclear cells (PBMCs) of healthy adult individuals. The PBMCs were reprogrammed using non-integrating Sendai vi
Externí odkaz:
https://doaj.org/article/f127ec15d76c4fbab92c69a6aa7bc4ae
Autor:
Jacqueline V. Schiesser, Thomas Loudovaris, Helen E. Thomas, Andrew G. Elefanty, Edouard G. Stanley
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract The identification of cell surface markers specific to pancreatic beta cells is important for both the study of islet biology and for investigating the pathophysiology of diseases in which this cell type is lost or damaged. Following analysi
Externí odkaz:
https://doaj.org/article/dcab1ff3fe334cd4b5b2b617cf023918
Autor:
Shicheng Sun, Jacky Y. Li, Hieu T. Nim, Adam Piers, Mirana Ramialison, Enzo R. Porrello, Igor E. Konstantinov, Andrew G. Elefanty, Edouard G. Stanley
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Thymic epithelium is critical for the structural integrity of the thymus and for T cell development. Within the fully formed thymus, large numbers of hematopoietic cells shape the thymic epithelium into a scaffold-like structure which bears little si
Externí odkaz:
https://doaj.org/article/78af4cce953b45bf916d16eb982f3b10
Autor:
Elvira Forte, Mirana Ramialison, Hieu T Nim, Madison Mara, Jacky Y Li, Rachel Cohn, Sandra L Daigle, Sarah Boyd, Edouard G Stanley, Andrew G Elefanty, John Travis Hinson, Mauro W Costa, Nadia A Rosenthal, Milena B Furtado
Publikováno v:
eLife, Vol 11 (2022)
Organ fibroblasts are essential components of homeostatic and diseased tissues. They participate in sculpting the extracellular matrix, sensing the microenvironment, and communicating with other resident cells. Recent studies have revealed transcript
Externí odkaz:
https://doaj.org/article/fdff1021c46d4d60aff391d8030addd1
Autor:
Soon‐Jung Park, Hyeok Kim, Sunghun Lee, Jongsoo Kim, Taek‐Hee Jung, Seong Woo Choi, Bong‐Woo Park, Sun‐Woong Kang, David A. Elliott, Edouard G. Stanley, Andrew G. Elefanty, Kiwon Ban, Hun‐Jun Park, Sung‐Hwan Moon
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 1, Pp n/a-n/a (2022)
Externí odkaz:
https://doaj.org/article/158ab481833743fda307f722b5fa0712
Autor:
Mugdha V. Joglekar, Subhshri Sahu, Wilson K.M. Wong, Sarang N. Satoor, Charlotte X. Dong, Ryan J. Farr, Michael D. Williams, Prapti Pandya, Gaurang Jhala, Sundy N.Y. Yang, Yi Vee Chew, Nicola Hetherington, Dhan Thiruchevlam, Sasikala Mitnala, Guduru V. Rao, Duvvuru Nageshwar Reddy, Thomas Loudovaris, Wayne J. Hawthorne, Andrew G. Elefanty, Vinay M. Joglekar, Edouard G. Stanley, David Martin, Helen E. Thomas, David Tosh, Louise T. Dalgaard, Anandwardhan A. Hardikar
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 5, Pp 1530-1553.e4 (2022)
Background & Aims: Pancreatic islet β-cells are factories for insulin production; however, ectopic expression of insulin also is well recognized. The gallbladder is a next-door neighbor to the developing pancreas. Here, we wanted to understand if ga
Externí odkaz:
https://doaj.org/article/3d728a223a8941f1b6deb7467c5a4e8a
Publikováno v:
Stem Cell Research, Vol 56, Iss , Pp 102547- (2021)
Insulin expressing beta cells and glucagon expressing alpha cells are the two most abundant endocrine cell types of the human pancreatic islet. Both alpha and beta cells can be generated in vitro via the differentiation of pluripotent stem cells (PSC
Externí odkaz:
https://doaj.org/article/30b65809393d4946a284841f44f2f580
Autor:
Shicheng Sun, Kevin Wijanarko, Oniko Liani, Kathleen Strumila, Elizabeth S. Ng, Andrew G. Elefanty, Edouard G. Stanley
Publikováno v:
Immunological Reviews. 315:154-170