Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Andrew Friedman"'
Autor:
Margarita M. Ivanova, Julia Dao, Neala Loynab, Sohailla Noor, Neil Kasaci, Andrew Friedman, Ozlem Goker-Alpan
Publikováno v:
Cells, Vol 13, Iss 8, p 716 (2024)
Background: Gaucher disease (GD) is caused by glucocerebrosidase (GCase) enzyme deficiency, leading to glycosylceramide (Gb-1) and glucosylsphingosine (Lyso-Gb-1) accumulation. The pathological hallmark for GD is an accumulation of large macrophages
Externí odkaz:
https://doaj.org/article/29e6db55d6a34a6ca779dba5aa3e06d8
Publikováno v:
Cells, Vol 12, Iss 16, p 2102 (2023)
Fabry disease (FD) is a lysosomal disorder caused by α-galactosidase A deficiency, resulting in the accumulation of globotriaosylceramide (Gb-3) and its metabolite globotriaosylsphingosine (Lyso-Gb-3). Cardiovascular complications and hypertrophic c
Externí odkaz:
https://doaj.org/article/6581602e81d745d0b37861167c52f2df
Autor:
Nicholas Alexander Bascou, Benjamin Haslund-Gourley, Katrina Amber-Monta, Kyle Samson, Nathaniel Goss, Dakota Meredith, Andrew Friedman, Andrew Needleman, Vishnu K. Kumar, Bradford D. Fischer
Publikováno v:
Harm Reduction Journal, Vol 19, Iss 1, Pp 1-12 (2022)
Abstract Background The opioid epidemic is a rapidly growing public health concern in the USA, as the number of overdose deaths continues to increase each year. One strategy for combating the rising number of overdoses is through opioid overdose prev
Externí odkaz:
https://doaj.org/article/f6ec75b57a0645118edac96e0086bb4a
Publikováno v:
Genetics in Medicine Open, Vol 1, Iss 1, Pp 100205- (2023)
Externí odkaz:
https://doaj.org/article/bfc59e77b9b34840aa2bff519155018e
Autor:
Margarita M. Ivanova, Julia Dao, Neil Kasaci, Andrew Friedman, Lauren Noll, Ozlem Goker-Alpan
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Patients with Gaucher disease (GD) have progressive bone involvement that clinically presents with debilitating bone pain, structural bone changes, bone marrow infiltration (BMI), Erlenmeyer (EM) flask deformity, and osteoporosis. Pain is referred by
Externí odkaz:
https://doaj.org/article/6aba249aabef40e69053a53eed745fb7
Autor:
Ritesh Kumar, Helene Kane, Qiong Wang, Ashley Hibberd, Henrik Max Jensen, Hye-Sook Kim, Steffen Yde Bak, Isabelle Auzanneau, Stéphanie Bry, Niels Christensen, Andrew Friedman, Pia Rasinkangas, Arthur C. Ouwehand, Sofia D. Forssten, Oliver Hasselwander
Publikováno v:
Cells, Vol 11, Iss 13, p 2084 (2022)
Akkermansia muciniphila is a well-known bacterium with the ability to degrade mucin. This metabolic capability is believed to play an important role in the colonization of this bacterium in the gut. In this study, we report the identification and cha
Externí odkaz:
https://doaj.org/article/dc7ff5ec22d448348b408ac355b743ba
Autor:
Jerzy Karczewski, Stephen P. Krasucki, Papa Nii Asare-Okai, Carl Diehl, Andrew Friedman, Christine M. Brown, Yukari Maezato, Stephen J. Streatfield
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
We have isolated and characterized a novel antibacterial peptide, CMB001, following an extensive screening effort of bacterial species isolated from diverse environmental sources. The bacterium that produces CMB001 is characterized as a Gram (+) baci
Externí odkaz:
https://doaj.org/article/5331988770cb4ad98c3b101da797f3b5
Autor:
Margaret A. Young, Andrew Friedman
Publikováno v:
AJIL Unbound, Vol 112, Pp 123-128 (2018)
International efforts to better conserve the marine biological diversity of areas beyond national jurisdiction (BBNJ) through a new international legally binding instrument1 are developing in a context of established norms and institutions. Existing
Externí odkaz:
https://doaj.org/article/e987f05c47f04cd6a67b4965227c5e15
Autor:
Andrew Friedman
Publikováno v:
Professions and Professionalism, Vol 9, Iss 1 (2019)
By denigrating expertise and challenging the value of evidence-based statements, advice and policies, populism challenges professions and professionalism. Arguably it is imperative for the professions to meet the challenge: but how? Here we provide a
Externí odkaz:
https://doaj.org/article/ff0d777a351f4dc8ab6f26ebc711732e
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0192033 (2018)
Administrative claims and electronic health records are valuable resources for evaluating pharmaceutical effects during pregnancy. However, direct measures of gestational age are generally not available. Establishing a reliable approach to infer the
Externí odkaz:
https://doaj.org/article/2c65c1e0ee7440388a85facaba93cb4a