Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Andrew Freiman"'
Autor:
Roger Pique-Regi, Cynthia A Kalita, Andrew Freiman, Xiaoquan Wen, Christopher D. Brown, Francesca Luca, Jenna Isherwood
Publikováno v:
Genome Research. 28:1701-1708
Many variants associated with complex traits are in noncoding regions and contribute to phenotypes by disrupting regulatory sequences. To characterize these variants, we developed a streamlined protocol for a high-throughput reporter assay, Biallelic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ef727bf3bcccb08536d6b95a3e15a3e
https://doi.org/10.1101/gr.237354.118
https://doi.org/10.1101/gr.237354.118
Publikováno v:
The Journal of Immunology. 206:20.33-20.33
House dust mites (HDM) are a predominant causative agent of airway hypersensitivity and asthma. The HDM group 1 allergens include Der p 1, a cysteine protease that contributes to sensitization and symptom exacerbation. Respiratory syncytial virus (RS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c11b1b57d66c67204105611e6ab3c39
https://doi.org/10.4049/jimmunol.206.supp.20.33
https://doi.org/10.4049/jimmunol.206.supp.20.33
Autor:
Christopher D. Brown, Jenna Isherwood, Cynthia A Kalita, Roger Pique-Regi, Andrew Freiman, Francesca Luca, Xiaoquan Wen
Many variants associated with complex traits are in non-coding regions, and contribute to phenotypes by disrupting regulatory sequences. To characterize these variants, we developed a streamlined protocol for a high-throughput reporter assay, BiT-STA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::240318954552e367df75578df92ff248
https://doi.org/10.1101/270991
https://doi.org/10.1101/270991
Genetic Ancestry and Natural Selection Drive Population Differences in Immune Responses to Pathogens
Autor:
Steven Hebert, Anne Dumaine, Luis B. Barreiro, Yohann Nédélec, Zachary A. Szpiech, Jean-Christophe Grenier, Alain Pacis, Joaquín Sanz, Aaron J. Sams, Vania Yotova, Ryan D. Hernandez, Andrew Freiman, Jenny Tung, Francesca Luca, Golshid Baharian, Ariane Pagé Sabourin, Ran Blekhman, Roger Pique-Regi
Publikováno v:
Cell. 167(3)
Individuals from different populations vary considerably in their susceptibility to immune-related diseases. To understand how genetic variation and natural selection contribute to these differences, we tested for the effects of African versus Europe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b14fdf5f3003ff2f5af34a6ce833729
https://pubmed.ncbi.nlm.nih.gov/27768889
https://pubmed.ncbi.nlm.nih.gov/27768889