Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Andrew Favor"'
Autor:
Sherry Bermeo, Andrew Favor, Ya-Ting Chang, Andrew Norris, Scott E. Boyken, Yang Hsia, Hugh K. Haddox, Chunfu Xu, T. J. Brunette, Vicki H. Wysocki, Gira Bhabha, Damian C. Ekiert, David Baker
Publikováno v:
Nature Structural & Molecular Biology. 29:1266-1276
The de novo design of three protein chains that associate to form a heterotrimer (but not any of the possible two-chain heterodimers) and that can drive the assembly of higher-order branching structures is an important challenge for protein design. W
Autor:
Natasha I Edman, Rachel L Redler, Ashish Phal, Thomas Schlichthaerle, Sanjay R Srivatsan, Ali Etemadi, Seong An, Andrew Favor, Devon Ehnes, Zhe Li, Florian Praetorius, Max Gordon, Wei Yang, Brian Coventry, Derrick R Hicks, Longxing Cao, Neville Bethel, Piper Heine, Analisa N Murray, Stacey Gerben, Lauren Carter, Marcos Miranda, Babak Negahdari, Sangwon Lee, Cole Trapnell, Lance Stewart, Damian C Ekiert, Joseph Schlessinger, Jay Shendure, Gira Bhabha, Hannele Ruohola-Baker, David Baker
Publikováno v:
bioRxiv
Growth factors and cytokines signal by binding to the extracellular domains of their receptors and drive association and transphosphorylation of the receptor intracellular tyrosine kinase domains, initiating downstream signaling cascades. To enable s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cabf19b52c9e40ae334b69d4789b7567
https://europepmc.org/articles/PMC10055045/
https://europepmc.org/articles/PMC10055045/
Autor:
Zhe Li, Shunzhi Wang, Una Nattermann, Asim K. Bera, Andrew J. Borst, Matthew J. Bick, Erin C. Yang, William Sheffler, Byeongdu Lee, Soenke Seifert, Hannah Nguyen, Alex Kang, Radhika Dalal, Joshua M. Lubner, Yang Hsia, Hugh Haddox, Alexis Courbet, Quinton Dowling, Marcos Miranda, Andrew Favor, Ali Etemadi, Natasha I. Edman, Wei Yang, Banumathi Sankaran, Babak Negahdari, David Baker
SummaryProtein crystallization plays a central role in structural biology1, with broad impact2in pharmaceutical formulation3, drug delivery4, biosensing5, and biocatalysis6,7. Despite this importance, the process of protein crystallization remains po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97c9e49b9bf954ca7ba67cff48a16384
https://doi.org/10.1101/2022.11.18.517014
https://doi.org/10.1101/2022.11.18.517014
Autor:
Andrew Favor, Ivan Jayapurna
This study analyzes and adds to the Low-N protein engineering with data-efficient deep learning work done by Biswas et al. We provide a complete, open-source, end-to-end re-implementation of the in silico protein engineering pipeline with improved co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d41a1410a0087b5118e73dc6a892bda
https://doi.org/10.22541/au.159683529.96283070
https://doi.org/10.22541/au.159683529.96283070