Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Andrew F. A. Marsden"'
Publikováno v:
Journal of Biological Chemistry. 269:8524-8528
The domain structure of the 6-deoxyerythronolide B synthase 1 component of the erythromycin-producing polyketide synthase from Saccharopolyspora erythraea has been investigated using limited proteolysis and active-site labeling. Trypsin, elastase, en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::26211c3b2dd423f9c37c58f2e9eb5766
https://doi.org/10.1016/s0021-9258(17)37226-5
https://doi.org/10.1016/s0021-9258(17)37226-5
Autor:
Jesús F. Aparicio, Jesus Cortes, Patrick Caffrey, Andrew F. A. Marsden, Debra J. Bevitt, Gareth A. Roberts, Peter F. Leadlay, James Staunton
Publikováno v:
Biochemical Society Transactions. 21:218-222
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c645694f7b86073339458babd43ba5ce
https://doi.org/10.1042/bst0210218
https://doi.org/10.1042/bst0210218
Autor:
Jesús F. Aparicio, Patrick Caffrey, Andrew F. A. Marsden, Peter F. Leadlay, Mark S. Loughran, James Staunton
Publikováno v:
Science (New York, N.Y.). 263(5145)
During assembly of complex polyketide antibiotics like erythromycin A, molecular recognition by the multienzyme polyketide synthase controls the stereochemical outcome as each successive methylmalonyl-coenzyme A (CoA) extender unit is added. Acylatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94c38088cd6eedcd3ab09336bbdcf828
https://pubmed.ncbi.nlm.nih.gov/8278806
https://pubmed.ncbi.nlm.nih.gov/8278806
Autor:
Jesús F. Aparicio, Torsten Schwecke, Andrew F. A. Marsden, Ian S. Galloway, István Molnár, Stephen F. Haydock, James Staunton, Ariane König, Peter F. Leadlay, Lake Ee Khaw
Publikováno v:
Haydock, S F, Aparicio, J F, Molnár, I, Schwecke, T, Khaw, L E, König, A, Marsden, A F A, Galloway, I S, Staunton, J & Leadlay, P F 1995, ' Divergent sequence motifs correlated with the substrate specificity of (methyl)malonyl-CoA:acyl carrier protein transacylase domains in modular polyketide synthases ', FEBS Letters, vol. 374, no. 2, pp. 246-248 . https://doi.org/10.1016/0014-5793(95)01119-Y
The amino acid sequences of a large number of polyketide synthase domains that catalyse the transacylation of either methylmalonyl-CoA or malonyl-CoA onto acyl carrier protein (ACP) have been compared. Regions were identified in which the acyltransfe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dc2159ec1f824b0e51131cbe4ba89ae
Autor:
Marsden, Andrew F.A., Wilkinson, Barrie, Cortes, Jesus, Dunster, Nicholas J., Staunton, James, Leadlay, Peter F.
Publikováno v:
Science. 1/9/1998, Vol. 279 Issue 5348, p199-202. 4p. 2 Diagrams.
Autor:
Marsden, Andrew F.A., Caffrey, Patrick
Publikováno v:
Science. 1/21/1994, Vol. 263 Issue 5145, p378. 3p. 6 Diagrams.
Autor:
Günther Jung
The story of success goes on and on - with a new book on combinatorial chemistry, edited by Gunther Jung! Combinatorial chemistry is a proven time- and resource-saving synthetic method of outstanding importance for industrial processes. Compound libr
