Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Andrew F Tyler"'
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e66772 (2013)
The exact mechanism of glatiramer acetate (GA, Copaxone®), an FDA-approved immunomodulatory therapy for multiple sclerosis (MS), remains unclear after decades of research. Previously, we have shown that GA therapy of MS induces CD8(+) T cell respons
Externí odkaz:
https://doaj.org/article/a1fe190c1f2e47a78d5f41c1aadaf85e
Autor:
Andrew F. Tyler, Chris Vincent, Nicole M. Stevens, Harris Payton, Robert H. Boyce, Cory A. Collinge, Phillip M. Mitchell
Publikováno v:
Journal of Orthopaedic Trauma. 37:e135-e138
Publikováno v:
Journal of Orthopaedic Trauma. 36:e437-e441
Periprosthetic tibial shaft fractures below total knee arthroplasty (TKA) are relatively rare, with an incidence of approximately 1%. However, as the rates of arthroplasty increase, orthopaedic surgeons are likely to see a corresponding increase in t
Publikováno v:
Journal of Orthopaedic Trauma. 36:339-342
To characterize the associated injuries, fixation constructs, and outcomes of extra-articular unstable iliac fractures.Retrospective cohort study.Level I trauma center.Thirty-three extra-articular unstable iliac fractures treated over a 20-year perio
Publikováno v:
Evidence-Based Orthopedics
Publikováno v:
Cureus. 14(3)
The opioid epidemic in the United States has forced care providers to seek out alternatives to narcotic analgesics. Physicians involved in trauma care, including orthopaedic trauma surgeons, often have patients requiring significant amounts of these
Autor:
Annamarie D. Horan, Jessica Kenia, Thomas Rose, Samir Mehta, Scott Day, Andrew F. Tyler, Derek J. Donegan
Publikováno v:
Foot & Ankle Orthopaedics
Foot & Ankle Orthopaedics, Vol 5 (2020)
Foot & Ankle Orthopaedics, Vol 5 (2020)
Background: Controversy continues regarding appropriate indications for posterior malleolus fracture fixation in unstable rotational trimalleolar ankle injuries, with limited data comparing gait in operatively treated trimalleolar ankle fractures vs
Publikováno v:
The Journal of the American Academy of Orthopaedic Surgeons. 25(10)
Computational models represent more than just finite element analysis, a term that many clinicians may know and globally apply. Over the past 30 years, many published studies have addressed clinically relevant orthopaedic questions with speed and pre
Autor:
Jason Mendoza, Nathan R. York, Nitin J. Karandikar, Sterling B. Ortega, Andrew Benagh, Mihail Firan, Andrew F. Tyler
Publikováno v:
Journal of Autoimmunity. 35:33-44
Immune-based self-recognition and failure to modulate this response are believed to contribute to the debilitating autoimmune pathology observed in multiple sclerosis (MS). Studies from its murine model, experimental autoimmune encephalomyelitis (EAE
Autor:
Nitin J. Karandikar, Jason Mendoza, Sterling B. Ortega, Khrishen Cunnusamy, Venkatesh P. Kashi, Andrew F. Tyler
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 191(1)
Multiple sclerosis (MS) is an immune-mediated demyelinating disease of the CNS, and CD8 T cells are the predominant T cell population in MS lesions. Given that transfer of CNS-specific CD8 T cells results in an attenuated clinical demyelinating disea