Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Andrew F Teich"'
Autor:
Hsin-Pei Wang, Rebeca Scalco, Naomi Saito, Laurel Beckett, My-Le Nguyen, Emily Z. Huie, Lawrence S. Honig, Charles DeCarli, Robert A. Rissman, Andrew F. Teich, Dan M. Mungas, Lee-Way Jin, Brittany N. Dugger
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-12 (2024)
Abstract Cerebrovascular and α-synuclein pathologies are frequently observed alongside Alzheimer disease (AD). The heterogeneity of AD necessitates comprehensive approaches to postmortem studies, including the representation of historically underrep
Externí odkaz:
https://doaj.org/article/2ccca9693bd8481a91ee168a49211a38
Autor:
Nicholas J Izzo, Agnes Staniszewski, Lillian To, Mauro Fa, Andrew F Teich, Faisal Saeed, Harrison Wostein, Thomas Walko, Anisha Vaswani, Meghan Wardius, Zanobia Syed, Jessica Ravenscroft, Kelsie Mozzoni, Colleen Silky, Courtney Rehak, Raymond Yurko, Patricia Finn, Gary Look, Gilbert Rishton, Hank Safferstein, Miles Miller, Conrad Johanson, Edward Stopa, Manfred Windisch, Birgit Hutter-Paier, Mehrdad Shamloo, Ottavio Arancio, Harry LeVine, Susan M Catalano
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e111898 (2014)
Synaptic dysfunction and loss caused by age-dependent accumulation of synaptotoxic beta amyloid (Abeta) 1-42 oligomers is proposed to underlie cognitive decline in Alzheimer's disease (AD). Alterations in membrane trafficking induced by Abeta oligome
Externí odkaz:
https://doaj.org/article/7588522c8af84352a18c72ff5aa5c7b2
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e55647 (2013)
Unraveling the normal physiologic role of β-amyloid is likely crucial to understanding the pathogenesis of Alzheimer's disease. However, progress on this question is currently limited by the high background of many ELISAs for murine β-amyloid. Here
Externí odkaz:
https://doaj.org/article/a96ee74a8d1f4f8694b4576ead10c140
Autor:
Tohid Siddiqui, Mehmet Ilyas Cosacak, Stanislava Popova, Prabesh Bhattarai, Elanur Yilmaz, Annie J. Lee, Yuhao Min, Xue Wang, Mariet Allen, Özkan İş, Zeynep Tansu Atasavum, Natalia Rodriguez-Muela, Badri N. Vardarajan, Delaney Flaherty, Andrew F. Teich, Ismael Santa-Maria, Uwe Freudenberg, Carsten Werner, Giuseppe Tosto, Richard Mayeux, Nilüfer Ertekin-Taner, Caghan Kizil
Publikováno v:
npj Regenerative Medicine, Vol 8, Iss 1, Pp 1-18 (2023)
Abstract Neurogenesis, crucial for brain resilience, is reduced in Alzheimer’s disease (AD) that induces astroglial reactivity at the expense of the pro-neurogenic potential, and restoring neurogenesis could counteract neurodegenerative pathology.
Externí odkaz:
https://doaj.org/article/bebfc2431c024aae887659ececd580cc
Autor:
Rebeca Scalco, Naomi Saito, Laurel Beckett, My-Le Nguyen, Emily Huie, Hsin-Pei Wang, Delaney A. Flaherty, Lawrence S. Honig, Charles DeCarli, Robert A. Rissman, Andrew F. Teich, Lee-Way Jin, Brittany N. Dugger
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-14 (2023)
Abstract Despite the increasing demographic diversity of the United States’ aging population, there remain significant gaps in post-mortem research investigating the ethnoracial heterogeneity in the neuropathological landscape of Alzheimer Disease
Externí odkaz:
https://doaj.org/article/c400d7d0dfbe4c4d88b0540088c7067d
Autor:
Adam M. Brickman, Jennifer J. Manly, Lawrence S. Honig, Danurys Sanchez, Dolly Reyes‐Dumeyer, Rafael A. Lantigua, Jean Paul Vonsattel, Andrew F. Teich, Min Suk Kang, Jeffrey L. Dage, Richard Mayeux
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 9, Iss 5, Pp 756-761 (2022)
Abstract Blood‐based phosphorylated tau (Ptau) 181 and 217 biomarkers are sensitive and specific for Alzheimer's disease. In this racial/ethnically diverse cohort study, participants were classified as biomarker positive (Ptau+) or negative (Ptau
Externí odkaz:
https://doaj.org/article/8351af1ece434fbaa5a178f235ff75b8
Autor:
Emily Z, Huie, Anthony, Escudero, Naomi, Saito, Danielle, Harvey, My-Le, Nguyen, Katherine L, Lucot, Jayne, LaGrande, Dan, Mungas, Charles, DeCarli, Melissa, Lamar, Julie A, Schneider, Alifiya, Kapasi, Robert A, Rissman, Andrew F, Teich, Brittany N, Dugger
Publikováno v:
Journal of Alzheimer's Disease. 91:1291-1301
Background: Transactive Response DNA Binding Protein 43 kDa (TDP-43) pathology is frequently found in cases with Alzheimer’s disease (AD). TDP-43 pathology is associated with hippocampal atrophy and greater AD severity denoted by cognition and clin
Autor:
Rebecca R Valentino, William J Scotton, Shanu F Roemer, Tammaryn Lashley, Michael G Heckman, Maryam Shoai, Alejandro Martinez-Carrasco, Nicole Tamvaka, Ronald L Walton, Matthew C Baker, Hannah L Macpherson, Raquel Real, Alexandra I Soto-Beasley, Kin Mok, Tamas Revesz, Thomas T Warner, Zane Jaunmuktane, Bradley F Boeve, Elizabeth A Christopher, Michael DeTure, Ranjan Duara, Neill R Graff-Radford, Keith A Josephs, David S Knopman, Shunsuke Koga, Melissa E Murray, Kelly E Lyons, Rajesh Pahwa, Joseph E Parisi, Ronald C Petersen, Jennifer Whitwell, Lea T Grinberg, Bruce Miller, Athena Schlereth, William W Seeley, Salvatore Spina, Murray Grossman, David J Irwin, Edward B Lee, EunRan Suh, John Q Trojanowski, Vivianna M Van Deerlin, David A Wolk, Theresa R Connors, Patrick M Dooley, Matthew P Frosch, Derek H Oakley, Iban Aldecoa, Mircea Balasa, Ellen Gelpi, Sergi Borrego-Écija, Rosa Maria de Eugenio Huélamo, Jordi Gascon-Bayarri, Raquel Sánchez-Valle, Pilar Sanz-Cartagena, Gerard Piñol-Ripoll, Laura Molina-Porcel, Eileen H Bigio, Margaret E Flanagan, Tamar Gefen, Emily J Rogalski, Sandra Weintraub, Javier Redding-Ochoa, Koping Chang, Juan C Troncoso, Stefan Prokop, Kathy L Newell, Bernardino Ghetti, Matthew Jones, Anna Richardson, Andrew C Robinson, Federico Roncaroli, Julie Snowden, Kieren Allinson, Oliver Green, James B Rowe, Poonam Singh, Thomas G Beach, Geidy E Serrano, Xena E Flowers, James E Goldman, Allison C Heaps, Sandra P Leskinen, Andrew F Teich, Sandra E Black, Julia L Keith, Mario Masellis, Istvan Bodi, Andrew King, Safa-Al Sarraj, Claire Troakes, Glenda M Halliday, John R Hodges, Jillian J Kril, John B Kwok, Olivier Piguet, Marla Gearing, Thomas Arzberger, Sigrun Roeber, Johannes Attems, Christopher M Morris, Alan J Thomas, Bret M. Evers, Charles L White, Naguib Mechawar, Anne A Sieben, Patrick P Cras, Bart B De Vil, Peter Paul P.P. De Deyn, Charles Duyckaerts, Isabelle Le Ber, Danielle Seihean, Sabrina Turbant-Leclere, Ian R MacKenzie, Catriona McLean, Matthew D Cykowski, John F Ervin, Shih-Hsiu J Wang, Caroline Graff, Inger Nennesmo, Rashed M Nagra, James Riehl, Gabor G Kovacs, Giorgio Giaccone, Benedetta Nacmias, Manuela Neumann, Lee-Cyn Ang, Elizabeth C Finger, Cornelis Blauwendraat, Mike A Nalls, Andrew B Singleton, Dan Vitale, Cristina Cunha, Agostinho Carvalho, Zbigniew K Wszolek, Huw R Morris, Rosa Rademakers, John A Hardy, Dennis W Dickson, Jonathan D Rohrer, Owen A Ross
Publikováno v:
medRxiv
BackgroundPick’s disease (PiD) is a rare and predominantly sporadic form of frontotemporal dementia that is classified as a primary tauopathy. PiD is pathologically defined by argyrophilic inclusion Pick bodies and ballooned neurons in the frontal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8eb436da4c7362a38f76655e19fddf0a
https://europepmc.org/articles/PMC10168402/
https://europepmc.org/articles/PMC10168402/
Publikováno v:
Journal of Neuroscience Research.
Autor:
Anne Marie W. Bartosch, Elliot H. H. Youth, Shania Hansen, Maria E. Kaufman, Harrison Xiao, So Yeon Koo, Archana Ashok, Sharanya Sivakumar, Rajesh K. Soni, Logan C. Dumitrescu, Tiffany G. Lam, Ali S. Ropri, Annie J. Lee, Hans-Ulrich Klein, Badri N. Vardarajan, David A. Bennett, Tracy L. Young-Pearse, Philip L. De Jager, Timothy J. Hohman, Andrew A. Sproul, Andrew F. Teich
Publikováno v:
bioRxiv
ZCCHC17 is a putative master regulator of synaptic gene dysfunction in Alzheimer’s Disease (AD), and ZCCHC17 protein declines early in AD brain tissue, before significant gliosis or neuronal loss. Here, we investigate the function of ZCCHC17 and it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a91b3c009ab5d9cf79e9c77deb1f14f2
https://doi.org/10.1101/2023.03.21.533654
https://doi.org/10.1101/2023.03.21.533654