Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Andrew F, Cumpstey"'
Autor:
Joseph Larvin, Mark Edwards, Daniel S. Martin, Martin Feelisch, Michael P.W. Grocott, Andrew F. Cumpstey
Publikováno v:
BJA Open, Vol 10, Iss , Pp 100277- (2024)
Summary: Oxygen is the most used drug in anaesthesia. Despite such widespread use, optimal perioperative oxygen administration remains highly controversial because of concerns about the competing harms of both hyperoxia and hypoxia.Notwithstanding a
Externí odkaz:
https://doaj.org/article/dfa85bef96c140319ae2a86a3320826b
Publikováno v:
Open Biology, Vol 13, Iss 9 (2023)
Diurnal and seasonal rhythmicity, entrained by environmental and nutritional cues, is a vital part of all life on Earth operating at every level of organization; from individual cells, to multicellular organisms, whole ecosystems and societies. Redox
Externí odkaz:
https://doaj.org/article/462388b321ae4a8aa5f9ff24c9dbffd1
Autor:
Ahilanandan Dushianthan, Luke Bracegirdle, Rebecca Cusack, Andrew F. Cumpstey, Anthony D. Postle, Michael P. W. Grocott
Publikováno v:
Medical Sciences, Vol 11, Iss 4, p 70 (2023)
Acute hypoxic respiratory failure (AHRF) is a prominent feature of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) critical illness. The severity of gas exchange impairment correlates with worse prognosis, and AHRF requiring mechanical v
Externí odkaz:
https://doaj.org/article/0efbc74ae7524461a2a979e4736e944d
Autor:
Andrew F. Cumpstey, BMBCh, Alex H. Oldman, BMBS, Daniel S. Martin, PhD, Andrew Smith, BMBS, Michael P. W. Grocott, MD
Publikováno v:
Critical Care Explorations, Vol 4, Iss 4, p e0652 (2022)
OBJECTIVES:. Patients admitted to intensive care often require treatment with invasive mechanical ventilation and high concentrations of oxygen. Mechanical ventilation can cause acute lung injury that may be exacerbated by oxygen therapy. Uncertainty
Externí odkaz:
https://doaj.org/article/a55021a56972474aa09347828abf90c8
Autor:
Philip J. Hennis, Andrew F. Cumpstey, Alasdair F. O’Doherty, Bernadette O. Fernandez, Edward T. Gilbert-Kawai, Kay Mitchell, Helen Moyses, Alexandra Cobb, Paula Meale, Helmut Pöhnl, Monty G. Mythen, Michael P. W. Grocott, Denny Z. H. Levett, Daniel S. Martin, Martin Feelisch, The Xtreme Alps Research Group, Adam Booth, Adam Sheperdigian, Alasdair O’Doherty, Alex Salam, Andrew Cumpstey, Bernadette Fernandez, Damian Mole, Daniel Grant, Daniel Martin, Denny Levett, Edith Kortekaas, Edward Gilbert, Fabio Rigat, Fiona Shrubb, Heng Yow, James Farrant, Jildou van der Kaaij, Jim Milledge, Jo Simpson, Laura Jackson, Liesl Wandrag, Lindsay Bisiker, Mark Edsell, Maryam Khosravi, Matt Sanborn, Michael Grocott, Michael Mythen, Nick Talbot, Oliver Burdall, Oliver Firth, Oliver Moses, Phil Hennis, Savini Wijesingha, Steve Dauncey, Tom Adams, Tom Woolley, Wilby Williamson, Will Jenner, Zeyn Mahomed
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
IntroductionNitrate supplementation in the form of beetroot juice (BRJ) ingestion has been shown to improve exercise tolerance during acute hypoxia, but its effect on exercise physiology remains unstudied during sustained terrestrial high altitude ex
Externí odkaz:
https://doaj.org/article/5874770ad0244740b9422554efa5fad6
Publikováno v:
Perioperative Medicine, Vol 8, Iss 1, Pp 1-4 (2019)
Externí odkaz:
https://doaj.org/article/aa673f6d24774340a14247ff94da327b
Autor:
Clare M. Morkane, Helen McKenna, Andrew F. Cumpstey, Alex H. Oldman, Michael P. W. Grocott, Daniel S. Martin, Pan London Perioperative Audit and Research Network (PLAN)
Publikováno v:
Perioperative Medicine, Vol 7, Iss 1, Pp 1-7 (2018)
Abstract Background Considerable controversy remains about how much oxygen patients should receive during surgery. The 2016 World Health Organization (WHO) guidelines recommend that intubated patients receive a fractional inspired oxygen concentratio
Externí odkaz:
https://doaj.org/article/1c84dbf8824341dcad0d2edf6d8a6a10
Autor:
Andrew F. Cumpstey, Magdalena Minnion, Bernadette O. Fernandez, Monika Mikus-Lelinska, Kay Mitchell, Daniel S. Martin, Michael P.W. Grocott, Martin Feelisch
Publikováno v:
Redox Biology, Vol 21, Iss , Pp - (2019)
The chemical and functional interactions between Reactive Oxygen (ROS), Nitrogen (RNS) and Sulfur (RSS) species allow organisms to detect and respond to metabolic and environmental stressors, such as exercise and altitude exposure. Whether redox mark
Externí odkaz:
https://doaj.org/article/4f44156f38eb4800a340f8f913540863
Autor:
C. Summers, M. Ferrari, Hugh Montgomery, S. R. Moonesinghe, Andrew F. Cumpstey, Ahilanandan Dushianthan, W. Thomas, Michael P. W. Grocott
Background Whilst the management of Coronavirus disease-2019 (COVID-19) has evolved in response to the emerging data, treating such patients remains a challenge, and many treatments lack robust clinical evidence. We conducted a survey to evaluate Int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab55c4e9e181a6810ccb013d9a855445
https://www.repository.cam.ac.uk/handle/1810/341517
https://www.repository.cam.ac.uk/handle/1810/341517
Autor:
Margaret McNeil, Norman R. Williams, Andrew F. Cumpstey, Chris Brew-Graves, Michael P.W. Grocott, Ronan O’Driscoll, Jia Liu Stevens, Rachel Burnish, Michael G. Mythen, Daniel Martin, Helder Filipe
Publikováno v:
J Intensive Care Soc
Background Despite oxygen being the commonest drug administered to critically ill patients we do not know which oxygen saturation (SpO2) target results in optimal survival outcomes in those receiving mechanical ventilation. We therefore conducted a f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0477ea299d576f2495f7d39f872b3ce4
https://doi.org/10.1177/17511437211010031
https://doi.org/10.1177/17511437211010031