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pro vyhledávání: '"Andrew Es Barentine"'
Autor:
Toma Tebaldi, Mark D. Lessard, Joshua T. Zimmer, Gabriella Viero, Poorval Joshi, Valentina Botti, Ashley Qin, Karla M. Neugebauer, Giulia Biancon, Torben Hunck, Rana Gbyli, Lea Kiefer, Andrew Es Barentine, Joerg Bewersdorf, Edward M. Courchaine, Yuanbin Song, Matthew D. Simon, Nils Neuenkirchen, Stephanie Halene, Martin Machyna, Haifan Lin, Amisha Patel, Yimeng Gao
Somatic mutations in splicing factors are of significant interest in myeloid malignancies and other cancers. U2AF1, together with U2AF2, is essential for 3’ splice site recognition. U2AF1 mutations result in aberrant splicing, but the molecular mec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee3ecf3e301da6963e53d2e34aaabe26
https://doi.org/10.1101/2021.04.22.441020
https://doi.org/10.1101/2021.04.22.441020
Autor:
Giulia Biancon, Poorval Joshi, Joshua T Zimmer, Torben Hunck, Yimeng Gao, Mark D Lessard, Edward Courchaine, Andrew ES Barentine, Martin Machyna, Valentina Botti, Ashley Qin, Rana Gbyli, Amisha Patel, Yuanbin Song, Lea Kiefer, Gabriella Viero, Nils Neuenkirchen, Haifan Lin, Joerg Bewersdorf, Matthew D Simon, Karla M Neugebauer, Toma Tebaldi, Stephanie Halene
Publikováno v:
Blood. 138:321-321
Somatic mutations in splicing factor genes are drivers of myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML). The splicing factors U2AF1 and U2AF2 form the U2AF heterodimer that is critical in the 3' splice site (3'SS) recognition and i