Zobrazeno 1 - 10
of 262
pro vyhledávání: '"Andrew Eisen"'
Publikováno v:
Clinical Neurophysiology Practice, Vol 9, Iss , Pp 1-12 (2024)
Amyotrophic lateral sclerosis (ALS) is a rapidly progressive neurodegenerative disorder of the human motor system, first described in the 19th Century. The etiology of ALS appears to be multifactorial, with a complex interaction of genetic, epigeneti
Externí odkaz:
https://doaj.org/article/6a9761c4835c44d7b149f438d8a588ca
Publikováno v:
Brain Sciences, Vol 14, Iss 5, p 471 (2024)
Plastic production, which exceeds one million tons per year, is of global concern. The constituent low-density polymers enable spread over large distances and micro/nano particles (MNPLs) induce organ toxicity via digestion, inhalation, and skin cont
Externí odkaz:
https://doaj.org/article/490a526b33fa4c50a18bb2254f5ea0cf
Autor:
Julia M. Wu, Mallorie T. Tam, Kirsten Buch, Fouziah Khairati, Laurissa Wilson, Elizabeth Bannerman, Alexandra Guerrero, Andrew Eisen, Wendy Toyer, Travis Stevenson, Julie M. Robillard
Publikováno v:
BMC Palliative Care, Vol 21, Iss 1, Pp 1-11 (2022)
Abstract Background Respite care provides caregiving support to people with amyotrophic lateral sclerosis (ALS) and their care partners by providing the care partner with temporary relief from their caregiving duties. The aim of this study was to exp
Externí odkaz:
https://doaj.org/article/deca27e3f7ed4518b2accdcd52e4e5fa
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
Amyotrophic lateral sclerosis and frontotemporal dementia (ALS/FTD) are neurodegenerations with evolutionary underpinnings, expansive clinical presentations, and multiple genetic risk factors involving a complex network of pathways. This perspective
Externí odkaz:
https://doaj.org/article/3ede570d8b5047c2b65a096831390359
Autor:
John J. Tentler, Julie Lang, Anna Capasso, Deog Joong Kim, Ely Benaim, Young B. Lee, Andrew Eisen, Stacey M. Bagby, Sarah J. Hartman, Betelehem W. Yacob, Brian Gittleman, Todd M. Pitts, Roberta Pelanda, S. Gail Eckhardt, Jennifer R. Diamond
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-13 (2020)
Abstract Background Triple-negative breast cancer (TNBC) is an aggressive breast cancer subtype with limited systemic treatment options. RX-5902 is a novel anti-cancer agent that inhibits phosphorylated-p68 and thus attenuates nuclear β-catenin sign
Externí odkaz:
https://doaj.org/article/1dcda43bbcb945d6ae883320daa5d648
Publikováno v:
BMC Biomedical Engineering, Vol 2, Iss 1, Pp 1-8 (2020)
Abstract Tourniquets in orthopaedic surgery safely provide blood free surgical fields, but their use is not without risk. Tourniquets can result in temporary or permanent injury to underlying nerves, muscles, blood vessels and soft tissues. Advances
Externí odkaz:
https://doaj.org/article/29b17ece60694fd38aae3171d966d873
Autor:
Andrew Eisen, Peter Bede
Publikováno v:
Brain and Behavior, Vol 11, Iss 12, Pp n/a-n/a (2021)
Abstract Background Split phenotypes, (split hand, elbow, leg, and foot), are probably unique to ALS, and are characterized by having a shared peripheral input of both affected and unaffected muscles. This implies an anatomical origin rostral to the
Externí odkaz:
https://doaj.org/article/8d26ee03c4c3446c98a32f9c63d08d3d
Autor:
Seth Tigchelaar, Femke Streijger, Sunita Sinha, Stephane Flibotte, Neda Manouchehri, Kitty So, Katelyn Shortt, Elena Okon, Michael A. Rizzuto, Ivana Malenica, Amanda Courtright-Lim, Andrew Eisen, Kendall Van Keuren-Jensen, Corey Nislow, Brian K. Kwon
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Abstract Therapeutic development for spinal cord injury is hindered by the difficulty in conducting clinical trials, which to date have relied solely on functional outcome measures for patient enrollment, stratification, and evaluation. Biological bi
Externí odkaz:
https://doaj.org/article/c6dd30671e5d45519ced5dd8ee820ad4
Autor:
Daniel J. Lenihan, MD, Sarah A. Anderson, ACNP, Carrie Geisberg Lenneman, MD, Evan Brittain, MD, MSCI, James A.S. Muldowney, III, MD, Lisa Mendes, MD, Ping Z. Zhao, PhD, Jennifer Iaci, MS, Stephen Frohwein, MD, Ronald Zolty, MD, PhD, Andrew Eisen, MD, PhD, Douglas B. Sawyer, MD, PhD, Anthony O. Caggiano, MD, PhD
Publikováno v:
JACC: Basic to Translational Science, Vol 1, Iss 7, Pp 576-586 (2016)
A first-in-human, phase 1, double blind, placebo-controlled, single ascending dose study examined the safety, tolerability, and exploratory efficacy of intravenous infusion of a recombinant growth factor, cimaglermin alfa, in patients with heart fail
Externí odkaz:
https://doaj.org/article/1b06ca8dbecb4850b7f6c85e6a80bdc0
Autor:
Andrew Eisen
Publikováno v:
Brain Sciences, Vol 11, Iss 3, p 300 (2021)
The site of origin of amyotrophic lateral sclerosis (ALS), although unsettled, is increasingly recognized as being cortico-fugal, which is a dying-forward process primarily starting in the corticomotoneuronal system. A variety of iterations of this c
Externí odkaz:
https://doaj.org/article/47a06aa1672d4b82b3eb26b9e543b0c8