Insights into the Evolution of Longevity from the Bowhead Whale Genome

Autor: Michael Keane, Jeremy Semeiks, Andrew E. Webb, Yang I. Li, Víctor Quesada, Thomas Craig, Lone Bruhn Madsen, Sipko van Dam, David Brawand, Patrícia I. Marques, Pawel Michalak, Lin Kang, Jong Bhak, Hyung-Soon Yim, Nick V. Grishin, Nynne Hjort Nielsen, Mads Peter Heide-Jørgensen, Elias M. Oziolor, Cole W. Matson, George M. Church, Gary W. Stuart, John C. Patton, J. Craig George, Robert Suydam, Knud Larsen, Carlos López-Otín, Mary J. O’Connell, John W. Bickham, Bo Thomsen, João Pedro de Magalhães

Publikováno v: Cell Reports, Vol 10, Iss 1, Pp 112-122 (2015)

The bowhead whale (Balaena mysticetus) is estimated to live over 200 years and is possibly the longest-living mammal. These animals should possess protective molecular adaptations relevant to age-related diseases, particularly cancer. Here, we report

Externí odkaz: https://doaj.org/article/5cb71fcc599b4343858c3cc10a216423

Erratum to: Surface layer proteins from virulent Clostridium difficile ribotypes exhibit signatures of positive selection with consequences for innate immune response

Autor: Mark Lynch, Thomas A. Walsh, Izabela Marszalowska, Andrew E. Webb, Micheál Mac Aogáin, Thomas R. Rogers, Henry Windle, Dermot Kelleher, Mary J. O’Connell, Christine E. Loscher

Publikováno v: BMC Evolutionary Biology, Vol 17, Iss 1, Pp 1-1 (2017)

Externí odkaz: https://doaj.org/article/376babb2367140a086c042465202603c

NAPS: Integrating pose estimation and tag-based tracking

Autor: Scott W. Wolf, Dee M. Ruttenberg, Daniel Y. Knapp, Andrew E. Webb, Ian M. Traniello, Grace C. McKenzie-Smith, Sophie A. Leheny, Joshua W. Shaevitz, Sarah D. Kocher

Significant advances in computational ethology have allowed the quantification of behavior in unprecedented detail. Tracking animals in social groups, however, remains challenging as most existing methods can either capture pose or robustly retain in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6aec274dd6e32db4eb371ec143327750
https://doi.org/10.1101/2022.12.07.518416

Adaptive Evolution in TRIF Leads to Discordance between Human and Mouse Innate Immune Signaling

Autor: Edel M Hyland, Andrew E Webb, Kathy F Kennedy, Z Nevin Gerek Ince, Christine E Loscher, Mary J O’Connell

Publikováno v: Hyland, E M, Webb, A E, Kennedy, K F, Gerek Ince, Z N, Loscher, C E & O'Connell, M J 2021, ' Adaptive Evolution in TRIF Leads to Discordance between Human and Mouse Innate Immune Signaling ', Genome biology and evolution, vol. 13, no. 12, evab268 . https://doi.org/10.1093/gbe/evab268
Genome Biology and Evolution

The TIR domain-containing adapter inducing IFN-β (TRIF) protein is an innate immune system protein that mediates the MyD88-independent toll-like receptor response pathway in mice and humans. Previously, we identified positive selection at seven dist

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b1da40d03b925496b9940bd3275e89b
https://nottingham-repository.worktribe.com/file/7345884/1/evab268

Convergent selection on hormone signaling shaped social evolution in bees

Autor: Beryl M. Jones, Benjamin E.R. Rubin, Olga Dudchenko, Callum J. Kingwell, Ian M. Traniello, Z. Yan Wang, Karen M. Kapheim, Eli S. Wyman, Per A. Adastra, Weijie Liu, Lance R. Parsons, S. RaElle Jackson, Katharine Goodwin, Shawn M. Davidson, Matthew J. McBride, Andrew E. Webb, Kennedy S. Omufwoko, Nikki Van Dorp, Mauricio Fernández Otárola, Melanie Pham, Arina D. Omer, David Weisz, Joshua Schraiber, Fernando Villanea, William T. Wcislo, Robert J. Paxton, Brendan G. Hunt, Erez Lieberman Aiden, Sarah D. Kocher

Life’s most dramatic innovations, from the emergence of self-replicating molecules to highly-integrated societies, often involve increases in biological complexity. Some groups traverse different levels of complexity, providing a framework to ident

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::aa7dac7bedf2acf58097a4718e4b4b47
https://doi.org/10.1101/2021.04.14.439731