Výsledky vyhledávání - "Andrew E. Resnick"

Akademický článek

Biased signaling by mutant EGFR underlies dependence on PKCα in lung adenocarcinoma

Autor: Mojtaba Sadeghi, Mohamed F. Salama, Sam B. Chiappone, Amy Huang, Andrew E. Resnick, Manoj Kandpal, Christopher J. Clarke, John D. Haley, Ramana V. Davuluri, Yusuf A. Hannun

Publikováno v: Cell Reports, Vol 43, Iss 12, Pp 115026- (2024)

Summary: Activating mutations in the epidermal growth factor receptor (EGFR) promote ligand-independent signaling; however, the mechanisms involved are poorly defined, and it is unknown whether this generates specific vulnerabilities. We previously o

Externí odkaz: https://doaj.org/article/ee7da34468014d86af2262d5cd62ca42

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Akademický článek

Transposon mutagenesis in Mycobacterium kansasii links a small RNA gene to colony morphology and biofilm formation and identifies 9,885 intragenic insertions that do not compromise colony outgrowth

Autor: William C. Budell, Gabrielle A. Germain, Niklas Janisch, Zaid McKie‐Krisberg, Anitha D. Jayaprakash, Andrew E. Resnick, Luis E. N. Quadri

Publikováno v: MicrobiologyOpen, Vol 9, Iss 4, Pp n/a-n/a (2020)

Abstract Mycobacterium kansasii (Mk) is a resilient opportunistic human pathogen that causes tuberculosis‐like chronic pulmonary disease and mortality stemming from comorbidities and treatment failure. The standard treatment of Mk infections requir

Externí odkaz: https://doaj.org/article/19b2b60fb976438ba8d8168356173733

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Dihydroceramide desaturase 1 (DES1) promotes anchorage-independent survival downstream of HER2-driven glucose uptake and metabolism

Autor: Ryan W. Linzer, Danielle L. Guida, Jonathan Aminov, Justin M. Snider, Gabrielle Khalife, A. Burak Buyukbayraktar, Charbel Alhaddad, Andrew E. Resnick, Pule Wang, Chun‐Hao Pan, Janet J. Allopenna, Christopher J. Clarke

Publikováno v: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 36(10)

Oncogenic reprogramming of cellular metabolism is a hallmark of many cancers, but our mechanistic understanding of how such dysregulation is linked to tumor behavior remains poor. In this study, we have identified dihydroceramide desaturase (DES1)-wh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e4b80768d9b0e33dcbca6bf2803dfaa
https://pubmed.ncbi.nlm.nih.gov/36165222

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Transposon mutagenesis inMycobacterium kansasiilinks a small RNA gene to colony morphology and biofilm formation and identifies 9,885 intragenic insertions that do not compromise colony outgrowth

Autor: Gabrielle Germain, Niklas Janisch, Zaid McKie-Krisberg, William C. Budell, Anitha D. Jayaprakash, Andrew E. Resnick, Luis E. N. Quadri

Publikováno v: MicrobiologyOpen, Vol 9, Iss 4, Pp n/a-n/a (2020)
MicrobiologyOpen

Mycobacterium kansasii (Mk) is a resilient opportunistic human pathogen that causes tuberculosis‐like chronic pulmonary disease and mortality stemming from comorbidities and treatment failure. The standard treatment of Mk infections requires costly

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c604e1cf233b77ebaa9f2fd67e3b9ae0
https://doi.org/10.1002/mbo3.988

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