Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Andrew E Messer"'
Autor:
Zeyu Yang, Alice M. Sheehan, Andrew E. Messer, Sharmane Tsui, Alexander Sparrow, Charles Redwood, Vladimir Kren, Ian R. Gould, Steven B. Marston
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
IntroductionAdrenergic activation of protein kinase A (PKA) in cardiac muscle targets the sarcolemma, sarcoplasmic reticulum, and contractile apparatus to increase contractile force and heart rate. In the thin filaments of the contractile apparatus,
Externí odkaz:
https://doaj.org/article/1cf510ec54604089a056970300248a0b
Autor:
Steven Marston, Cecile Montgiraud, Alex B Munster, O'Neal Copeland, Onjee Choi, Cristobal Dos Remedios, Andrew E Messer, Elisabeth Ehler, Ralph Knöll
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0138568 (2015)
BackgroundStudies of the functional consequences of DCM-causing mutations have been limited to a few cases where patients with known mutations had heart transplants. To increase the number of potential tissue samples for direct investigation we perfo
Externí odkaz:
https://doaj.org/article/21b7a55348dd474487eea475a9a01194
Autor:
Andrew E. Messer, Jasmine Chan, Alex Daley, O'Neal Copeland, Steven B. Marston, David J. Connolly
Publikováno v:
Frontiers in Physiology, Vol 8 (2017)
Hypertrophic cardiomyopathy (HCM) is the most common single gene inherited cardiomyopathy. In cats (Felix catus) HCM is even more prevalent and affects 16% of the outbred population and up to 26% in pedigree breeds such as Maine Coon and Ragdoll. Hom
Externí odkaz:
https://doaj.org/article/a15b31b712f7450db776b864cdd7c907
Autor:
Maria Papadaki, Adam Jacques, Andrew E. Messer, Emma Dyer, Steven B. Marston, Christopher R. Bayliss, Massimiliano Memo
Publikováno v:
Biophysical Reviews
Human heart samples from the Sydney Heart Bank have become a de facto standard against which others can be measured. Crucially, the heart bank contains a lot of donor heart material: for most researchers this is the hardest to obtain and yet is neces
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8ff120f274e2e5ba4c5aa1024e0aee2
https://doi.org/10.1007/s12551-020-00740-2
https://doi.org/10.1007/s12551-020-00740-2
Autor:
Andrew E. Messer, Corrado Poggesi, Andrew Jabbour, Sanjay K Prasad, O'Neal Copeland, Steven B. Marston
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Frontiers in Physiology
Frontiers in Physiology
In previous studies of septal heart muscle from HCM patients with hypertrophic obstructive cardiomyopathy (HOCM, LVOT gradient 50–120 mmHg) we found that the level of phosphorylation of troponin I (TnI) and myosin binding protein C (MyBP-C) was ext
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cb4544aca32335a343879b081d6a058
https://www.frontiersin.org/article/10.3389/fphys.2020.00241/full
https://www.frontiersin.org/article/10.3389/fphys.2020.00241/full
Autor:
Zachery R. Gregorich, Ying Ge, Zachary Hite, Wenxuan Cai, Andrew E. Messer, Sean J. McIlwain, Steve Marston, Takushi Kohmoto, Zhijie Wu, Ziqing Lin, Beini Lyu
Publikováno v:
Journal of Molecular and Cellular Cardiology. 122:11-22
Despite advancements in symptom management for heart failure (HF), this devastating clinical syndrome remains the leading cause of death in the developed world. Studies using animal models have greatly advanced our understanding of the molecular mech
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cec58e59c45a31bc88e6ab2d0f2bb588
https://doi.org/10.1016/j.yjmcc.2018.07.247
https://doi.org/10.1016/j.yjmcc.2018.07.247
Publikováno v:
Journal of Muscle Research and Cell Motility. 38:421-435
In both humans and mice, the Glu-99-Lys (E99K) mutation in the cardiac actin gene (ACTC) results in little understood apical hypertrophic cardiomyopathy (AHCM). To determine how cross-bridge kinetics change with AHCM development, we applied sinusoida
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce2d55d525a0c62ee4d37a097becb34e
https://doi.org/10.1007/s10974-018-9492-1
https://doi.org/10.1007/s10974-018-9492-1
Autor:
Petr G. Vikhorev, Natalia Smoktunowicz, Alex B. Munster, O’Neal Copeland, Sawa Kostin, Cecile Montgiraud, Andrew E. Messer, Mohammad R. Toliat, Amy Li, Cristobal G. dos Remedios, Sean Lal, Cheavar A. Blair, Kenneth S. Campbell, Maya Guglin, Manfred Richter, Ralph Knöll, Steven B. Marston
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Dilated cardiomyopathy (DCM) is an important cause of heart failure. Single gene mutations in at least 50 genes have been proposed to account for 25–50% of DCM cases and up to 25% of inherited DCM has been attributed to truncating mutations in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doajarticles::e945ae18c928e39d291b567d6a75b229
http://link.springer.com/article/10.1038/s41598-017-13675-8
http://link.springer.com/article/10.1038/s41598-017-13675-8
Autor:
O' Neal Copeland, Sawa Kostin, Cécile Montgiraud, Andrew E. Messer, Natalia Smoktunowicz, Manfred Richter, Maya Guglin, Alex B Munster, Kenneth S. Campbell, Steven B. Marston, Ralph Knöll, Amy Li, Petr G. Vikhorev, Cristobal G. dos Remedios, Cheavar A. Blair, Sean Lal, Mohammad R. Toliat
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-2 (2018)
A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12f8e6543aac70292a88adb16fe71bd0
https://doi.org/10.1038/s41598-018-32408-z
https://doi.org/10.1038/s41598-018-32408-z
Autor:
Alice Sheehan, Andrew E. Messer, Maria Papadaki, Afnan Choudhry, Vladimír Kren, David Biedermann, Brian Blagg, Anuj Khandelwal, Steven B. Marston
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
The inherited cardiomyopathies, hypertrophic cardiomyopathy (HCM) and dilated cardiomyopathy (DCM) are relatively common, potentially life-threatening and currently untreatable. Mutations are often in the contractile proteins of cardiac muscle and ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::ec62d256cb21bbf07693ef106bdd13f3
http://hdl.handle.net/10044/1/57853
http://hdl.handle.net/10044/1/57853
