Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Andrew Doedens"'
Autor:
Daniel Gray, Andrew Doedens, Michael Mingueneau, Melanie Greter, Nageswara Rao Tata, Daigo Hashimoto, Emmanuel Gautier, Tracy Heng, Roi Gazit, Deepali Malhotra, Anne Fletcher, Julie Helft, Lydia Lynch, Maelig Morvan, Arthur Mortha
Publikováno v:
Nature Reviews Immunology. 12:734-740
Although the field has a long collaborative tradition, immunology has made less use than genetics of 'consortium biology', wherein groups of investigators together tackle large integrated questions or problems. However, immunology is naturally suited
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66c4af0d0747f430958608b663b8d3a6
https://doi.org/10.1038/nri3300
https://doi.org/10.1038/nri3300
Autor:
Petros A, Tyrakis, Asis, Palazon, David, Macias, Kian L, Lee, Anthony T, Phan, Pedro, Veliça, Jia, You, Grace S, Chia, Jingwei, Sim, Andrew, Doedens, Alice, Abelanet, Colin E, Evans, John R, Griffiths, Lorenz, Poellinger, Ananda W, Goldrath, Randall S, Johnson
Publikováno v:
Nature. 540(7632)
R-2-hydroxyglutarate accumulates to millimolar levels in cancer cells with gain-of-function isocitrate dehydrogenase 1/2 mutations. These levels of R-2-hydroxyglutarate affect 2-oxoglutarate-dependent dioxygenases. Both metabolite enantiomers, R- and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e43577e7dff325b2b08eced994fb35fb
https://pubmed.ncbi.nlm.nih.gov/28009351
https://pubmed.ncbi.nlm.nih.gov/28009351
Autor:
Andrew, Doedens, Randall S, Johnson
Publikováno v:
Methods in enzymology. 435
The hypoxia-inducible factor (HIF) is a heterodimeric basic helix-loop-helix (bHLH) transcription factor that controls the mammalian cellular transcriptional response to low oxygen tension by up-regulating genes including glycolytic enzymes and angio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c5156205def59968526ab5526df4ac24
https://pubmed.ncbi.nlm.nih.gov/17998050
https://pubmed.ncbi.nlm.nih.gov/17998050
Publikováno v:
The Journal of Immunology. 190:117.10-117.10
The forkhead DNA binding domain, O subgroup of transcription factors (FOXO) integrate a range of extracellular signals including growth factor and nutrient availability, and assimilate these to subsequent downstream FOXO TF activity to modulate cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ec328b53d8ad985a2c7fd27a7cceced
https://doi.org/10.4049/jimmunol.190.supp.117.10
https://doi.org/10.4049/jimmunol.190.supp.117.10
Publikováno v:
Europe PubMed Central
Cadherins are homophilic cell adhesion molecules that control development of a variety of tissues and maintenance of adult structures. Although cadherins have been implicated in the development of the brain, including the visual system, in several ve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::4b1ed880574b036e6a50260b6b80f94c
http://europepmc.org/abstract/med/12020083
http://europepmc.org/abstract/med/12020083
