Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Andrew Danziger"'
Autor:
Brian K. Meyer, Debbie Nahas, Myunggi An, Andrew Danziger, Jeffrey Smith, Manish Patel, Shu-An Lin, Alexa Gleason, Kara Cox, Robert Capen, John Howe, Andrew Bett
Publikováno v:
Vaccine: X, Vol 16, Iss , Pp 100420- (2024)
Described here is the evaluation of a luciferase (luc) and respiratory syncytial virus (RSV) messenger RNA / lipid nanoparticle (mRNA/LNP) vaccine using a Needle-free Injection System, Tropis®, from PharmaJet® (Golden, Colorado USA). Needle-free je
Externí odkaz:
https://doaj.org/article/36511318351348fe92dd3417c22f13ce
Autor:
Suraj Patel, Vinodkumar Velayudhan, Andrew Danziger, Stephen Waite, Aslan Efendizade, Arcadi Grigorian
Publikováno v:
Journal of Clinical Neuroscience. 72:114-118
Fluoroscopic-guided lumbar puncture (LP) is a procedure commonly performed by radiologists, which in some circumstances may be difficult or impossible using a traditional posterior interspinous or interlaminar approach. Alternatives to LP include cer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dcdf0bedc3d2ea563cb3c52a276acd0
https://doi.org/10.1016/j.jocn.2019.12.056
https://doi.org/10.1016/j.jocn.2019.12.056
Autor:
Richard L. Kraus, Ronald M. Kim, Jeanine E. Ballard, Thomas J. Greshock, Andrea K. Houghton, Michelle K. Clements, Marie A. Holahan, Andrew Danziger, Christopher S. Burgey, Yuxing Li, Mark E. Layton, Jordi Serra, Parul S. Pall, Rebecca M. Klein, Joshua D. Vardigan, Dan Zhou, Fuqiang Zhao, Christopher Daley, Darrell A. Henze
Publikováno v:
Science Translational Medicine. 13
Humans with loss-of-function mutations in the Nav1.7 channel gene (SCN9A) show profound insensitivity to pain, whereas those with gain-of-function mutations can have inherited pain syndromes. Therefore, inhibition of the Nav1.7 channel with a small m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2568b727c558da3b3a2a03b719a658df
https://doi.org/10.1126/scitranslmed.aay1050
https://doi.org/10.1126/scitranslmed.aay1050
Autor:
Richard L, Kraus, Fuqiang, Zhao, Parul S, Pall, Dan, Zhou, Joshua D, Vardigan, Andrew, Danziger, Yuxing, Li, Christopher, Daley, Jeanine E, Ballard, Michelle K, Clements, Rebecca M, Klein, Marie A, Holahan, Thomas J, Greshock, Ronald M, Kim, Mark E, Layton, Christopher S, Burgey, Jordi, Serra, Darrell A, Henze, Andrea K, Houghton
Publikováno v:
Science translational medicine. 13(594)
Humans with loss-of-function mutations in the Na
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f9833016998efa2956e0258637677db9
https://pubmed.ncbi.nlm.nih.gov/34011626
https://pubmed.ncbi.nlm.nih.gov/34011626
Autor:
Chi-Chung Li, Rebecca B. White, Christopher S. Burgey, Ian M. Bell, Christopher P. Regan, Pradeep Banerjee, Eric L. Moore, Eric D. Hostetler, Maria S. Michener, Mark E. Fraley, Andrew Danziger, Christopher A. Salvatore
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. :jpet.119.261065
A growing body of evidence has implicated the calcitonin gene-related peptide (CGRP) receptors in migraine pathophysiology. With the recent approval of monoclonal antibodies targeting CGRP or the CGRP receptor, the inhibition of CGRP-mediated signali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05b26dcdc16b1afed1529fe6ca90194e
https://doi.org/10.1124/jpet.119.261065
https://doi.org/10.1124/jpet.119.261065
Autor:
Christopher P. Regan, Zhizhen Zeng, David L. Williams, Harold G. Selnick, Rebecca B. White, John F. Fay, Amy Calamari, Cyrille Sur, Stacey O'Malley, Stefanie A. Kane, Samuel Graham, Joseph P. Vacca, Andrew Danziger, Christopher A. Salvatore, Eric L. Moore, Patricia Miller, Maria S. Michener, Nicole T. Pudvah, Steven N. Gallicchio, Jacquelynn J. Cook, Ian M. Bell, Joseph J. Lynch, Yui S. Tang, Chi-Chung Li
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 333:152-160
Calcitonin gene-related peptide (CGRP) has long been hypothesized to play a key role in migraine pathophysiology, and the advent of small-molecule antagonists has clearly demonstrated a clinical link between blocking the CGRP receptor and migraine ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2c73bc77acb2f21270304bf4825ffd2
https://doi.org/10.1124/jpet.109.163816
https://doi.org/10.1124/jpet.109.163816
Autor:
Amy G. Quigley, Daniel V. Paone, Melody Mcwherter, Andrew Danziger, Brendan M. Crowley, Mark E. Fraley, Danny Gauvreau, Dan Cui, Karsten Menzel, J. Christopher Culberson, Joseph G. Bruno, Vijay Bhasker G. Reddy, Christopher A. Salvatore, Ian M. Bell, Craig A. Stump, Christopher S. Burgey, Eric L. Moore, Stefanie A. Kane, Amanda L. Kemmerer, Scott D. Mosser, Christine Fandozzi, Diem N. Nguyen, Craig M. Potteiger, Harold G. Selnick, Rebecca B. White
Publikováno v:
Bioorganicmedicinal chemistry letters. 25(21)
In our efforts to develop CGRP receptor antagonists as backups to MK-3207, 2, we employed a scaffold hopping approach to identify a series of novel oxazolidinone-based compounds. The development of a structurally diverse, potent (20, cAMP+HS IC50=0.6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::daf3aa4e8fe72f15e10763373e410d9a
https://pubmed.ncbi.nlm.nih.gov/26231160
https://pubmed.ncbi.nlm.nih.gov/26231160
Selective activation of the M1 muscarinic acetylcholine receptor achieved by allosteric potentiation
Autor:
Denise J. Bickel, Lone Veng, Marlene A. Jacobson, William J. Ray, K. H. Jones, Cyrille Sur, Danette Pascarella, Marion Wittmann, Rose Flick, Michelle Pearson, Constantine Kreatsoulas, Paul J. Shughrue, Scott M. Doran, Craig W. Lindsley, Gene G. Kinney, Matthew A. Seager, Guy R. Seabrook, Alexander McCampbell, Maryann Burno, William D. Shipe, Valerie Kuzmick Graufelds, Andrew Danziger, Lei Ma, Christopher P. Regan, Scott D. Kuduk, Guangping Xu, Susan L. Garson, Renee C. Gaspar
The forebrain cholinergic system promotes higher brain function in part by signaling through the M 1 muscarinic acetylcholine receptor (mAChR). During Alzheimer's disease (AD), these cholinergic neurons degenerate, therefore selectively activating M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::883d52a829eb7f4a1dfa08990154309a
https://europepmc.org/articles/PMC2732705/
https://europepmc.org/articles/PMC2732705/
Autor:
William J. Ray, Michelle Pearson, Christopher P. Regan, Marion Wittmann, Guy R. Seabrook, Guangping Xu, Susan L. Garson, Andrew Danziger, John J. Renger, Scott M. Doran
Publikováno v:
Alzheimer's & Dementia. 4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::efc725e8f98eed4ef425315671eaa5d6
https://doi.org/10.1016/j.jalz.2008.05.2402
https://doi.org/10.1016/j.jalz.2008.05.2402