Adenocarcinoma risk in gastric atrophy and intestinal metaplasia: a systematic review

Autor: Andrew D. Spence, Chris R. Cardwell, Úna C. McMenamin, Blanaid M. Hicks, Brian T. Johnston, Liam J. Murray, Helen G. Coleman

Publikováno v: BMC Gastroenterology, Vol 17, Iss 1, Pp 1-9 (2017)

Abstract Background Gastric cancer (GC) has a poor prognosis with wide variation in survival rates across the world. Several studies have shown premalignant lesions gastric atrophy (GA) and intestinal metaplasia (IM) influence gastric cancer risk. Th

Externí odkaz: https://doaj.org/article/aea39d0c6b7142a9850a642099d1de3f

Furosemide use and survival in patients with esophageal or gastric cancer: a population-based cohort study

Autor: Andrew D. Spence, Úna C. McMenamin, Christopher Cardwell, Brian T. Johnston, Helen G. Coleman, Peipei Liu

Publikováno v: BMC Cancer, Vol 19, Iss 1, Pp 1-12 (2019)
Liu, P, McMenamin, Ú C, Spence, A D, Johnston, B T, Coleman, H G & Cardwell, C R 2019, ' Furosemide use and survival in patients with esophageal or gastric cancer : a population-based cohort study ', BMC Cancer, vol. 19, no. 1, pp. 1017 . https://doi.org/10.1186/s12885-019-6242-8
BMC Cancer

Background Pre-clinical studies have shown that furosemide slows cancer cell growth by acting on the Na-K-2Cl transporter, particularly for gastric cancer cells. However, epidemiological studies have not investigated furosemide use and mortality in g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e9b007ff0856c556b872e23c87c40fd
http://link.springer.com/article/10.1186/s12885-019-6242-8

Hormonal and reproductive factors and risk of upper gastrointestinal cancers in men: A prospective cohort study within the UK Biobank

Autor: Christopher Cardwell, Andrew T. Kunzmann, Marie M. Cantwell, Brian T. Johnston, Liam J. Murray, Úna C. Mc Menamin, Andrew D. Spence, Michael B. Cook

Publikováno v: International Journal of Cancer. 143:831-841

Incidence of upper gastrointestinal cancers of the oesophagus and stomach show a strong unexplained male predominance. Hormonal and reproductive factors have been associated with upper gastrointestinal cancers in women but there is little available d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b01e5785dc39db31e2b9b53568161dcb
https://doi.org/10.1002/ijc.31375

Blood biomarkers for early diagnosis of oesophageal cancer

Autor: Úna C. McMenamin, Richard C. Turkington, Andrew D. Spence, Helen G. Coleman, Ronan T. Gray, Liam J. Murray, Andrew T. Kunzmann

Publikováno v: European Journal of Gastroenterology & Hepatology. 30:263-273

Background Oesophageal cancer prognosis remains poor owing to the inability to detect the disease at an early stage. Nontissue (serum, urinary or salivary) biomarkers potentially offer less invasive methods to aid early detection of oesophageal cance

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee0ce4489f2115aebcc3e8da5b83b0c7
https://doi.org/10.1097/meg.0000000000001029

Statin use after esophageal cancer diagnosis and survival: A population based cohort study

Autor: Liam J. Murray, Andrew D. Spence, Christopher Cardwell, Carmel Hughes

Publikováno v: Cardwell, C, Spence, A D, Hughes, C M & Murray, L J 2017, ' Statin use after esophageal cancer diagnosis and survival A population based cohort study ', Cancer epidemiology, vol. 48, pp. 124-130 . https://doi.org/10.1016/j.canep.2017.04.015

BACKGROUND: A recent epidemiological study of esophageal cancer patients concluded statin use post-diagnosis was associated with large (38%) and significant reductions in cancer-specific mortality. We investigated statin use and cancer-specific morta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34a851ad865683c3425a604c40100cfe
https://doi.org/10.1016/j.canep.2017.04.015