Zobrazeno 1 - 10
of 156
pro vyhledávání: '"Andrew D. Roberts"'
Autor:
Rhiannon E. H. Jones, Peter Aspin, Suzanne H. Davies, Inderjit Mann, Catherine Priestley, Andrew D. Roberts, Natalia Zotova-Eldridge, John H. Leahy
Publikováno v:
Organic Process Research & Development. 26:2646-2655
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb146cae618bf70ba15acdd8860dbbe0
https://doi.org/10.1021/acs.oprd.2c00048
https://doi.org/10.1021/acs.oprd.2c00048
Autor:
Andrew D. Roberts, John Besser, Josh Hundley, David E. Mosby, Amanda Rosenberger, Kristen L. Bouska, Bryan R. Simmons, Stephen E. McMurray, Scott Faiman, Leslie Lueckenhoff
Publikováno v:
Science of The Total Environment. 876:162743
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::807289f1666814c5a1bff6905317cbd7
https://doi.org/10.1016/j.scitotenv.2023.162743
https://doi.org/10.1016/j.scitotenv.2023.162743
Autor:
Andrew J. Edwards, Amanda Giddings, Kathryn Payne, Paul Stonestreet, Mike Sasse, Michael Urquhart, Alec Simpson, Steve Smith, Angela White, Neil G. Stevenson, Sophie Druot-Houllemare, Steve Etridge, Robert A. Reid, James Harvey, Erika Etridge, Bernie M. Choudary, Andrew D. Roberts, John H. Leahy, Neil Hodnett, Thierry Boyer
Publikováno v:
Organic Process Research & Development. 24:371-386
The development of the synthetic process to the PPAR-α receptor antagonist 5-((4-(tert-butoxy)-3-methylphenoxy)methyl)-3-(4-(tert-butyl)phenyl)-1,2,4-oxadiazole (GW641597X) 1 is described. The disc...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a81241c41d19b4f98f897512f644d979
https://doi.org/10.1021/acs.oprd.9b00385
https://doi.org/10.1021/acs.oprd.9b00385
Autor:
John J. McAtee, Jacques Briand, David J. Behm, Karl F. Erhard, Andrew D. Roberts, Ralph A. Rivero, Brian G. Lawhorn, Joseph E. Pero, Grazyna Graczyk-Millbrandt, Dennis A. Holt
Publikováno v:
ACS Med Chem Lett
[Image: see text] GSK2798745, an antagonist of the transient receptor potential vanilloid 4 (TRPV4) ion channel, was recently investigated in clinical trials for the treatment of cardiac and respiratory diseases. Human plasma and urine samples collec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b6d51b5ede72ceaac42c737d6c5900d
https://europepmc.org/articles/PMC8436415/
https://europepmc.org/articles/PMC8436415/
Autor:
Kevin R. Murray, MSc, Jessica A. Poirier, MSc, Jason S. Au, PhD, Eric T. Hedge, MSc, Andrew D. Robertson, PhD, George A. Heckman, MD, Richard L. Hughson, PhD
Publikováno v:
CJC Open, Vol 5, Iss 12, Pp 870-880 (2023)
Background: Insufficient cardiac output in individuals with heart failure (HF) limits daily functioning and reduces quality of life. Although lower cerebral perfusion, secondary to limitations in cardiac output, has been observed during moderate-inte
Externí odkaz:
https://doaj.org/article/8e19e6273d004873bc110be5f4577318
Autor:
Andrew D. Roberts
Publikováno v:
Handbook of Smart Cities ISBN: 9783030151454
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5b33a31752e067a610996d11326a72f
https://doi.org/10.1007/978-3-030-15145-4_30-1
https://doi.org/10.1007/978-3-030-15145-4_30-1
Autor:
Andrew D. Roberts, Peter Francis, Paola Grandi, Emma J. Jones, David P. Dixon, Robert J. Watson, Christina Rau, Peter Pogány, Angela Bridges, Chun-wa Chung, Darren Jason Mitchell, Rab K. Prinjha, Peter D. Craggs, Kelly Locke, Emmanuel Hubert Demont, Anne-Marie Michon, Bhumika Karamshi, Rebecca C. Furze, Paul Bamborough, Robert J. Sheppard, Simon C. C. Lucas, Ana Maria Roa
Publikováno v:
Journal of medicinal chemistry. 62(16)
The bromodomain of ATAD2 has proved to be one of the least-tractable proteins within this target class. Here, we describe the discovery of a new class of inhibitors by high-throughput screening and show how the difficulties encountered in establishin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f80874ffd274bf81cab3a201c3f2f1c
https://pubmed.ncbi.nlm.nih.gov/31398032
https://pubmed.ncbi.nlm.nih.gov/31398032
Autor:
Christina S. Barr, Julie A. Larson, Mary L. Schneider, Leslie M. Resch, Colleen F. Moore, Miriam M. Adkins, Andrew D. Roberts
Publikováno v:
Child Development. 88:183-197
Neonatal sensory processing (tactile and vestibular function) was tested in 78 rhesus macaques from two experiments. At ages 4–5 years, striatal dopamine D2 receptor binding was examined using positron emission tomography. At ages 5–7 years, adul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4230c87b67e167a95cea047d750652f5
https://doi.org/10.1111/cdev.12572
https://doi.org/10.1111/cdev.12572
Autor:
Andrew D. Roberts, Eamonn Reading, Claire Beaumont, Carol V. Robinson, Gordon J. Dear, Jordi Munoz-Muriedas
Publikováno v:
Analytical Chemistry. 88:2273-2280
Ion mobility-mass spectrometry (IM-MS) in combination with molecular modeling offers the potential for small molecule structural isomer identification by measurement of their gas phase collision cross sections (CCSs). Successful application of this a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::502caeeb442f41593c7b2cd80fd70468
https://doi.org/10.1021/acs.analchem.5b04068
https://doi.org/10.1021/acs.analchem.5b04068