Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Andrew D. Kohler"'
Autor:
Tenzeela Ilyas, Keith Taylor, George J. Ellames, Andrew D. Kohler, Sascha Hartmann, David M. Whitehead
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 56:36-41
[carboxyl-(14) C]Celivarone was synthesised from barium [(14) C]carbonate with overall radiochemical yields in the range 49-53%. The synthetic route involves [(14) C]carbonylation methodology, which both decreased the number of synthetic steps and in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24ffdfffd4f695789819b2dcceff7058
https://doi.org/10.1002/jlcr.3009
https://doi.org/10.1002/jlcr.3009
Autor:
George J. Ellames, Catherine Noban, Teyrnon C. Jones, Alan C. Spivey, Andrew D. Kohler, Laetitia J. Martin
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 50:281-285
Strategies for the use of germanium-based linkers for the phase-tagged synthesis of isotopically labelled intermediates are described. Protocols of potential use in the devolatilization of volatile intermediates prepared from [ 14 C]-CO 2 and [ 14 C]
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::841a3782d76028af988f0b08e52754e7
https://doi.org/10.1002/jlcr.1302
https://doi.org/10.1002/jlcr.1302
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 48:285-294
Iridium(I) complexes 1, containing bidentate phosphines, and 3, with arsine ligands, are generated in situ. These species mediate hydrogen isotope exchange in a variety of aromatic substrates including benzyl ketones. Although the catalytic activitie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de0bf48766cab721d36bfda6bf09536d
https://doi.org/10.1002/jlcr.921
https://doi.org/10.1002/jlcr.921
Autor:
R. M. Van der Meulen, Mervyn J. Lewis, Mei Wang, Michael H. Beale, Andrew D. Kohler, Ruth Rollason, D. H. Paul Barratt
Publikováno v:
Journal of the Chemical Society, Perkin Transactions 1. :1543-1548
The construction of a photoaffinity probe based on abscisic acid is described. A strategy based on C-4′-tethering of aromatic hydrazides led to abscisic acid 4′-(3″-azido-4″ -hydroxybenzoylhydrazide). This compound is of moderate biological a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::705842c99ea49ec7ae415102c6464536
https://doi.org/10.1039/a607307g
https://doi.org/10.1039/a607307g
Autor:
David M, Whitehead, Sascha, Hartmann, Tenzeela, Ilyas, Keith R, Taylor, Andrew D, Kohler, George J, Ellames
Publikováno v:
Journal of labelled compoundsradiopharmaceuticals. 56(2)
[carboxyl-(14) C]Celivarone was synthesised from barium [(14) C]carbonate with overall radiochemical yields in the range 49-53%. The synthetic route involves [(14) C]carbonylation methodology, which both decreased the number of synthetic steps and in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6d7a28681fffe709b7cc6d76a455e203
https://pubmed.ncbi.nlm.nih.gov/24285280
https://pubmed.ncbi.nlm.nih.gov/24285280
A method for the parallel solid-phase synthesis (SPS) of iodinated analogues of Sanofi-Aventis' type 1 cannabinoid (CB1) receptor inverse agonist rimonabant (acomplia) has been developed. The method allows the synthesis of a range of C3 amide/hydrazi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbd49165106877fecdba78923ce1a10b
http://hdl.handle.net/10044/1/15223
http://hdl.handle.net/10044/1/15223
Publikováno v:
Organicbiomolecular chemistry. 6(22)
Syntheses of two 4-phenylpiperidines from bromobenzene have been developed involving anchoring to a fluorous-tag, Ir-catalysed borylation, Pd- and Co-catalysed elaboration then traceless cleavage. Although performed using 'cold' (i.e. unlabelled) bro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f34b00a906daa9582f96fc372985e5bc
https://pubmed.ncbi.nlm.nih.gov/18972036
https://pubmed.ncbi.nlm.nih.gov/18972036
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 55:497-498
1,4-Diiodobenzene was monolithiated with n-butyllithium and subsequently carboxylated with 14CO2 in 86% yield. The resulting [carboxyl-14C]-4-iodobenzoic acid was used in the synthesis of [carboxamido-14C]SAR240550, [carboxamido-14C]Iniparib. Copyrig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::553c256abc5c55c70c42fa51ce861e06
https://doi.org/10.1002/jlcr.2983
https://doi.org/10.1002/jlcr.2983
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 50:607-608
Keywords: germanium; immobilization of [14C]-bromobenzene; immobilization of [14C]-phenol; iridium-catalyzed C–H activation/borylation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ec16d4464ba5bb8cb804e1a1ebfbbd6
https://doi.org/10.1002/jlcr.1304
https://doi.org/10.1002/jlcr.1304
Publikováno v:
Synfacts. 2010:0115-0115
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6368b4fe56884d34bf43b2754925a340
https://doi.org/10.1055/s-0029-1218442
https://doi.org/10.1055/s-0029-1218442