Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Andrew D. Johnston"'
Publikováno v:
JAAD Case Reports, Vol 44, Iss , Pp 23-26 (2024)
Externí odkaz:
https://doaj.org/article/e1c34d276d7440a8b7b130364e6854c2
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-18 (2022)
Abstract In fragmented DNA, PCR-based methods quantify the number of intact regions at a specific amplicon length. However, the relationship between the population of DNA fragments within a sample and the likelihood they will amplify has not been ful
Externí odkaz:
https://doaj.org/article/5ac55ee6589946a4949a874ad498cc79
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Liquid biopsy assays for minimal residual disease (MRD) are used to monitor and inform oncological treatment and predict the risk of relapse in cancer patients. To-date, most MRD assay development has focused on targeting somatic mutations. However,
Externí odkaz:
https://doaj.org/article/19956497539d450ebf6d0e1d9f6c3cab
Autor:
Netha Ulahannan, Ronald Cutler, Reanna Doña-Termine, Claudia A. Simões-Pires, N. Ari Wijetunga, Matthew McKnight Croken, Andrew D. Johnston, Yu Kong, Shahina B. Maqbool, Masako Suzuki, John M. Greally
Publikováno v:
PLoS ONE, Vol 17, Iss 9 (2022)
To gain insights into the molecular interactions of an intracellular pathogen and its host cell, we studied the gene expression and chromatin states of human fibroblasts infected with the Apicomplexan parasite Toxoplasma gondii. We show a striking ac
Externí odkaz:
https://doaj.org/article/6f12feeadc7d4393b1d1509860d7e244
Autor:
Andrew D. Johnston, Claudia A. Simões-Pires, Taylor V. Thompson, Masako Suzuki, John M. Greally
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Functional variants have been proposed to alter transcription factor binding. Here, the authors provide direct evidence that functional variants within the TBC1D4 gene, encoding an NFκB binding site, can alter transcription factor binding, and use C
Externí odkaz:
https://doaj.org/article/88d29a982eee4fd9b508af61899db295
Autor:
Andrew D. Johnston, Paul R. Ebert
Publikováno v:
Journal of Toxicology, Vol 2012 (2012)
Oxidative stress is a toxic state caused by an imbalance between the production and elimination of reactive oxygen species (ROS). ROS cause oxidative damage to cellular components such as proteins, lipids, and nucleic acids. While the role of ROS in
Externí odkaz:
https://doaj.org/article/a03302687984458490099dff33159edf
Autor:
Allison Kutner, H. Dean Hosgood, Steven R. Cohen, Michelle A. Lowes, Morayma Reyes Gil, Kayla M. Babbush, Andrew D. Johnston, Mondana H. Ghias
Publikováno v:
Journal of the American Academy of Dermatology. 86:954-956
In fragmented DNA, PCR-based methods quantify the number of intact regions at a specific amplicon length. However, the relationship between the population of DNA fragments within a sample and the likelihood they will amplify has not been fully descri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e0bbce8804d59f9f48a2c4d285b7f33e
https://doi.org/10.21203/rs.3.rs-1728412/v1
https://doi.org/10.21203/rs.3.rs-1728412/v1
Functional Genomics of the Pediatric Obese Asthma Phenotype Reveal Enrichment of Rho-GTPase Pathways
Autor:
Yurydia Jorge, John Nico, Masako Suzuki, Andrew D. Johnston, Fernando Macian, John M. Greally, Lip Nam Loh, Deepa Rastogi
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 202:259-274
Rationale: Obesity-related asthma disproportionately affects minority children and is associated with nonatopic T-helper type 1 (Th1) cell polarized inflammation that correlates with pulmonary func...
Autor:
Alali Abdulrazak, Andrew D. Johnston, Shahina Maqbool, Masako Suzuki, Claudia A. Simões-Pires, Hanae Sato, John M. Greally
Publikováno v:
The CRISPR journal. 3(3)
The CRISPR/Cas9 system can be modified to perform ‘epigenetic editing’ by utilizing the catalytically-inactive (dead) Cas9 (dCas9) to recruit regulatory proteins to specific genomic locations. In prior studies, epigenetic editing with multimers o