Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Andrew D. Gnann"'
Autor:
Madison Knapp, Minshik Jo, Courtney L. Henthorn, Marley Brimberry, Andrew D. Gnann, Daniel P. Dowling, Jennifer Bridwell-Rabb
Publikováno v:
ACS Bio & Med Chem Au, Vol 4, Iss 6, Pp 353-370 (2024)
Externí odkaz:
https://doaj.org/article/d18b03418c3b471e92207d13ded59263
Publikováno v:
Current opinion in chemical biology. 72
Ox-/thiazoline groups in nonribosomal peptides are formed by a variant of peptide-forming condensation domains called heterocyclization (Cy) domains and appear in a range of pharmaceutically important natural products and virulence factors. Recent cr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69cc61f295473287a26691abfec5b4d0
https://pubmed.ncbi.nlm.nih.gov/36402006
https://pubmed.ncbi.nlm.nih.gov/36402006
Autor:
Andrew D. Gnann, Yuan Xia, Jess Soule, Clara Barthélemy, Jayata S. Mawani, Sarah Nzikoba Musoke, Brian M. Castellano, Edward J. Brignole, Dominique P. Frueh, Daniel P. Dowling
Publikováno v:
The Journal of biological chemistry. 298(10)
Nonribosomal peptide synthetase heterocyclization (Cy) domains generate biologically important oxazoline/thiazoline groups found in natural products, including pharmaceuticals and virulence factors such as some siderophores. Cy domains catalyze conse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::951dc7070078b5ee3dacfcb3614c582f
https://pubmed.ncbi.nlm.nih.gov/36063993
https://pubmed.ncbi.nlm.nih.gov/36063993
Autor:
Jonathan Webb, Jeremy J.M. Liew, Andrew D. Gnann, MacKenzie Patterson, Sayantanee Paul, Marta Forés, Gerardo Jiménez, Alexey Veraksa, Daniel P. Dowling
The HMG-box protein Capicua (CIC) is an evolutionarily conserved transcriptional repressor with key functions in development and disease-associated processes. CIC binds DNA using an exclusive mechanism that requires both its HMG-box and a separate do
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::36e72d3756da3754f99d3f89c4157a39
https://doi.org/10.1101/2022.03.28.485992
https://doi.org/10.1101/2022.03.28.485992
Autor:
Andrew D. Gnann, Yuan Xia, Jess Soule, Clara Barthélemy, Jayata Mawani, Sarah Nzikoba Musoke, Brian Castellano, Edward Brignole, Dominique Frueh, Daniel P. Dowling
Nonribosomal peptide synthetase (NRPS) heterocyclization (Cy) domains generate biologically important ox-/thiazoline modifications in natural products, including in production of compounds targeting disease or siderophores that are important for bact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::caac9211b1dcc011cbe078e156653250
https://doi.org/10.1101/2022.03.18.483834
https://doi.org/10.1101/2022.03.18.483834